2 Works

Cangrelor: Safe and Effective for Left Ventricular Assist Device Thrombosis

Roopa Rao, Eve Anderson, Mark Jones, Muhamed Safiia & Maya Guglin
Pump thrombosis is a devastating complication of left ventricular assist device implantation as it increases the risk of mortality and morbidity. Early and effective treatment is important to prevent the progression of the clot and to avoid the surgical need for pump exchange or heart transplant. The current strategies of intensifying anticoagulation therapy are not consistently effective and carry significant bleeding risks. Cangrelor is a new pharmacological agent that has been utilized as an antiplatelet...

Unusual Case of Pump Thrombosis in LVAD Patient with COVID-19 — Diagnostic Challenges

William H. Frick, Ryan D. Mallory, Maya Guglin, Eve Anderson, Erin N. Lushin, Rey P. Vivo, Kashif Saleem & Roopa A. Rao
We present the first reported case of left ventricular assist device (LVAD) pump thrombosis in the setting of the coronavirus pandemic. We describe the clinical features of the case which helped to differentiate coronavirus disease 19 (COVID-19) from LVAD pump thrombosis. The patient is 56-year-old female supported by destination LVAD therapy. She was originally implanted with a HeartMate II device in 2015 and underwent two pump exchanges in 2017 and 2019 for pump thrombosis, despite...

Registration Year

  • 2021
    2

Resource Types

  • Data Paper
    2

Affiliations

  • Indiana University
    2
  • Community Health Network
    2