3 Works

Data from: A mouse model of cochlear implantation with chronic electric stimulation

Alexander D. Claussen, René Vielman Qeuvedo, Brian Mostaert, Jonathon R. Kirk, Wolfram F. Dueck & Marlan R. Hansen
Objectives: Cochlear implants provide an effective treatment option for those with severe hearing loss, including those with preserved low frequency hearing. However, certain issues can reduce implant efficacy including intracochlear tissue response and delayed loss of residual acoustic hearing. We describe a mouse model of cochlear implantation with chronic electric stimulation that can be used to study cochlear implant biology and related pathologies. Methods: Twelve normal hearing adult CBA/J mice underwent unilateral cochlear implantation and...

Data from: Parasite resistance predicts fitness better than fecundity in a natural population of the freshwater snail Potamopyrgus antipodarum

Dorota Paczesniak, Kirsten Klappert, Kirstin Kopp, Maurine Neiman, Katri Seppälä, Curtis M. Lively & Jukka Jokela
The cost of males should give asexual females an advantage when in competition with sexual females. In addition, high-fecundity asexual genotypes should have an advantage over low-fecundity clones, leading to reduction in clonal diversity over time. To evaluate fitness components in a natural population, we measured the annual reproductive rate of individual sexual and asexual female Potamopyrgus antipodarum, a New Zealand freshwater snail, in field enclosures that excluded competitors and predators. We used allozyme genotyping...

Abnormal Development of Cerebellar-Striatal Circuitry in Huntington’s Disease: Supplemental Figures

Jordan Schultz, Alexander Tereshchenko, Joel Bruss, Vincent Magnotta, Eric Epping & Peg Nopoulos
Objective: To test the hypothesis that the trajectory of functional connections over time of the striatum and the cerebellum differs between pre-symptomatic patients with the HD gene expansion (GE) and patients with a family history of HD but without the gene-expansion (GNE), we evaluated function MRI data from the Kids-HD study. Methods: We utilized resting-state, functional MRI data from participants in the Kids-HD study between 6 to 18 years old. Participants were divided into the...

Registration Year

  • 2019
    3

Resource Types

  • Dataset
    3

Affiliations

  • University of Iowa
    3
  • Swiss Federal Institute of Aquatic Science and Technology
    1
  • Indiana University Bloomington
    1