2 Works

Data from: Evidence for a time-invariant phase variable in human ankle control

Robert D. Gregg, Elliott J. Rouse, Levi J. Hargrove & Jonathon W. Sensinger
Human locomotion is a rhythmic task in which patterns of muscle activity are modulated by state-dependent feedback to accommodate perturbations. Two popular theories have been proposed for the underlying embodiment of phase in the human pattern generator: a time-dependent internal representation or a time-invariant feedback representation (i.e., reflex mechanisms). In either case the neuromuscular system must update or represent the phase of locomotor patterns based on the system state, which can include measurements of hundreds...

Data from: Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk

Claire R. Quilter, Wendy N. Cooper, Kerry M. Cliffe, Benjamin M. Skinner, Philippa M. Prentice, LaTasha Nelson, Julien Bauer, Ken K. Ong, Constância Miguel, William L. Lowe, Nabeel A. Affara & David B. Dunger
Size at birth, postnatal weight gain, and adult risk for type 2 diabetes may reflect environmental exposures during developmental plasticity and may be mediated by epigenetics. Both low birth weight (BW), as a marker of fetal growth restraint, and high birth weight (BW), especially after gestational diabetes mellitus (GDM), have been linked to increased risk of adult type 2 diabetes. We assessed DNA methylation patterns using a bead chip in cord blood samples from infants...

Registration Year

  • 2014
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  • Dataset
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Affiliations

  • Northwestern University
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  • Northwestern University
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  • University of Cambridge
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  • Rehabilitation Institute of Chicago
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  • Medical Research Council
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  • Massachusetts Institute of Technology
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  • The University of Texas at Dallas
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  • University of New Brunswick
    1