11 Works

Neural, functional, and aesthetic impacts of spatially heterogeneous flicker: a potential role of natural flicker

Satoru Suzuki
Spatially heterogeneous flicker, characterized by probabilistic and locally independent luminance modulations, abounds in nature. It is generated by flames, water surfaces, rustling leaves, and so on, and it is pleasant to the senses. It affords spatiotemporal multistability that allows sensory activation conforming to the biases of the visual system, thereby generating the perception of spontaneous motion and likely facilitating the calibration of motion detectors. One may thus hypothesize that spatially heterogeneous flicker might potentially provide...

Data from: Network-targeted stimulation engages neurobehavioral hallmarks of age-related memory decline

Aneesha S. Nilakantan, M.-Marsel Mesulam, Sandra Weintraub, Erica L. Karp, Stephen VanHaerents & Joel L. Voss
Objective: To test whether targeting hippocampal-cortical brain networks with high-frequency transcranial magnetic stimulation (TMS) in older adults influences behavioral and neural measures characteristic of age-related memory impairment. Methods: Fifteen adults aged 64 – 80 years (mean = 72 years) completed a single-blind, sham-controlled experiment. Stimulation targets in parietal cortex were determined based on functional magnetic resonance imaging (fMRI) connectivity with the hippocampus. Recollection and recognition memory were assessed after five consecutive daily sessions of full-intensity...

Data from: Delimitation of the new tribe Parartocarpeae (Moraceae) is supported by a 333- gene phylogeny and resolves tribal level Moraceae taxonomy

Nyree J. C. Zerega & Elliot M. Gardner
Here we describe the new tribe, Parartocarpeae, within the Moraceae (mulberry family). The tribe comprises two small Malesian genera, Parartocarpus and Hullettia, and brings the total number of Moraceae tribes to seven. Evidence for this new designation comes from a phylogeny based on 333 nuclear genes sequenced using target enrichment via hybridization (hybseq). Morphological characters that set Parartocarpeae apart from other Moraceae tribes include the combination of the following characters: lateral nonamplexicaul stipules, spirally arranged...

Data from: Social and ecological factors alter stress physiology of Virunga mountain gorillas (Gorilla beringei beringei)

Winnie Eckardt, Tara S. Stoinski, Stacy Rosenbaum & Rachel Santymie
Living in a rapidly changing environment can alter stress physiology at the population level, with negative impacts on health, reproductive rates, and mortality that may ultimately result in species decline. Small, isolated animal populations where genetic diversity is low are at particular risks, such as endangered Virunga mountain gorillas (Gorilla beringei beringei). Along with climate change‐associated environmental shifts that are affecting the entire population, subpopulations of the Virunga gorillas have recently experienced extreme changes in...

Data from: Aversion to playing God predicts negative moral judgments of technology and science

Adam Waytz & Liane Young
This research provides, to our knowledge, the first systematic empirical investigation of people's aversion to playing God. Seven studies validate this construct and show its association with negative moral judgements of science and technology. Motivated by three nationally representative archival datasets that demonstrate this relationship, studies 1 and 2 demonstrate that people condemn scientific procedures they perceive to involve playing God. Studies 3–5 demonstrate that dispositional aversion to playing God corresponds to decreased willingness to...

Variations in the Intensity and Spatial Extent of Tropical Cyclone Precipitation

Danielle Touma, Samantha Stevenson, Suzana Camargo, Daniel Horton & Noah Diffenbaugh
The intensity and spatial extent of tropical cyclone precipitation (TCP) often shapes the risk posed by landfalling storms. Here we provide a comprehensive climatology of landfalling TCP characteristics as a function of tropical cyclone strength, using daily precipitation station data and Atlantic US landfalling tropical cyclone tracks from 1900-2017. We analyze the intensity and spatial extent of ≥ 1 mm/day TCP (Z1) and ≥ 50 mm/day TCP (Z50). We show that the highest median intensity...

Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry

Pan Liu, Laith Ali, Benjamin R Thomson, Jeffery N Savas & Jing Jin
The lenticular fiber cells are comprised of extremely long-lived proteins while still maintaining an active biochemical state. Dysregulation of these activities has been implicated in age-related cataracts, and other lens diseases. However, the lenticular protein dynamics underlying health and disease is unclear. We sought to measure the global protein turnover rates in the eye using dietary nitrogen-15 (15N)-labeling of mice between 3 and 15 weeks of age. By performing mass spectrometry we measured the 14N-...

Data from: A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis

Xia Jiang, Alan Wells, Adam Brufsky & Richard Neapolitan
Objective: A Clinical Decision Support System (CDSS) that can amass Electronic Health Record (EHR) and other patient data holds promise to provide accurate classification and guide treatment choices. Our objective is to develop the Decision Support System for Making Personalized Assessments and Recommendations Concerning Breast Cancer Patients (DPAC), which is a CDSS learned from data that recommends the optimal treatment decisions based on a patient’s features. Method: We developed a Bayesian network architecture called Causal...

Data from: Coordination of rapid cholinergic and dopaminergic signaling in striatum during spontaneous movement

Mark Howe, Imane Ridouh, Anna LA Mascaro, Alyssa Larios, Maite Azcorra Sedano & Daniel Dombeck
Interplay between dopaminergic and cholinergic neuromodulation in the striatum is crucial for movement control, with prominent models proposing pro-kinetic and anti-kinetic effects of dopamine and acetylcholine release, respectively. However, the natural, movement-related signals of striatum cholinergic neurons and their relationship to simultaneous variations in dopamine signaling are unknown. Here, functional optical recordings in mice were used to establish rapid cholinergic signals in dorsal striatum during spontaneous movements. Bursts across the cholinergic population occurred at transitions...

Data from: Profile of and risk factors for post-stroke cognitive impairment in diverse ethno-regional groups

Jessica W Lo, John D Crawford, David W Desmond, Olivier Godefroy, Hanna Jokinen, Simin Mahinrad, Hee-Joon Bae, Sebastian Köhler, Elles Douven, Julie Staals, Christopher Chen, Xin Xu, Eddie J Chong, Rufus O Akinyemi, Rajesh N Kalaria, Adesola Ogunniyi, Mélanie Barbay, Martine Roussel, Byung-Chul Lee, Velandai K Srikanth, Christopher Moran, Nagaendran Kandiah, Russell J Chander, Behnam Sabayan, J. Wouter Jukema … & Perminder S Sachdev
OBJECTIVE: To address the variability in prevalence estimates and inconsistencies in potential risk factors for post-stroke cognitive impairment (PSCI) using a standardised approach and individual participant data (IPD) from international cohorts in the STROKOG consortium. METHODS: We harmonised data from thirteen studies based in eight countries. Neuropsychological test scores 2 to 6 months after stroke or TIA and appropriate normative data were used to calculate standardised cognitive domain scores. Domain-specific impairment was based on percentile...

Time Series Data for Chicago, 1840-1973

Wesley G. Skogan
This study presents time-series demographic, economic, and political data for Chicago, covering each year from 1840 to 1973. Included are election returns, indicators of ethnic and racial composition of the city, political structure, municipal court operations, judicial recruitment, police activities, and selected municipal expenditures. Economic variables measure employment, unemployment, and manufacturing activities. National and local election returns and data on ethnic composition are also provided for individual city wards for each decade between 1890 and...

Registration Year

  • 2019

Resource Types

  • Dataset


  • Northwestern University
  • Seoul National University Bundang Hospital
  • Stanford University
  • Columbia University
  • Lincoln Park Zoo
  • Centre Hospitalier Universitaire D' Amiens
  • University of Pittsburgh
  • Newcastle University
  • National University of Singapore
  • Monash University