21 Works

Supplementary data 2: Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy

Kirsten McCaffery, Rachael Dodd, Erin Cvejic, Julie Ayre, Carys Batcup, Jennifer Isautier, Tessa Copp, Carissa Bonner, Kristen Pickles, Brooke Nickel, Thomas Dakin, Samuel Cornell & Michael S Wolf
Supplementary data for Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy. Table S1. Knowledge, attitudes, beliefs and behaviours related to COVID-19 in full analysis sample.

Midsea - Mantle Investigation of the Deep Suture between Eurasia and Africa

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Four institutions decided to populate the Mediterranean region with more BB instruments in the same time period and call our collective experiments MIDSEA. ETH put out 12 stations in 5 countries, UNSA/CNRS put 6 stations in France and italy, CIW put 5 stations in the Azores, and INGV put 2 stations in Italy. Two of the ETH stations are available at Geofon (MELI) and Inst. of Catalan Studies (POBL, autodrm) data centers, respectively. The other...

Seed size and capitulum position drive germination and dormancy responses to projected warming for the threatened dune endemic Cirsium pitcheri (Asteraceae)

Finote Gijsman & Pati Vitt
Among coastal plant species at risk from rapid environmental changes is the North American Great Lakes dune endemic Cirsium pitcheri. Despite being listed as federally threatened, little is known about how C. pitcheri seed attributes influence germination and dormancy-break patterns in the context of climate change. Following a previous work where we found differences in the number and weight of C. pitcheri seeds among capitulum positions and study sites, here we examine the effects of...

Resource competition shapes biological rhythms and promotes temporal niche differentiation in a community simulation

Vance Gao, Sara Morley-Fletcher, Stefania Maccari, Martha Vitaterna & Fred Turek
This is the code and dataset for the article entitled "Resource competition shapes biological rhythms and promotes temporal niche differentiation in a community simulation," in the journal Ecology and Evolution. Competition for resources often contributes strongly to defining an organism’s ecological niche. Endogenous biological rhythms are important adaptations to the temporal dimension of niches, but how other organisms influence such temporal niches have not been much studied, and the role of competition in particular has...

Supplemental materials for: Implementation and evaluation of an objective structured clinical examination (OSCE) tool for neurology post-graduate trainees in Lusaka, Zambia

Rebecca DiBiase
Introduction: Despite the high burden of neurologic disease in Zambia, a low-middle income sub-Saharan African country of 18 million people, there are currently no Zambian neurologists. We established the first neurology residency program in Zambia at the University of Zambia School of Medicine and the University Teaching Hospital in Lusaka. We evaluated the feasibility and effectiveness of a modified Objective Structured Clinical Examination (OSCE) to assess clinical skills. Program Description: The neurology training program began...

Data from: Absolute axial growth and trunk segmentation in the early Cambrian trilobite Oryctocarella duyunensis

Tao Dia, Nigel Hughes, Xingliang Zhang, Giuseppe Fusco & Nigel Hughes
A short stratigraphic interval near Bulin in western Hunan (China) yields multiple specimens of the ~514 Ma old oryctocarine trilobite Oryctocarella duyunensis. Size data obtained from these specimens indicates that, from meraspid degree 1 onwards, degrees represent successive instars. Meraspid growth persisted until a terminal stage was reached, providing the first example of determinate growth in trilobites and, notably, in an early Cambrian species. The sample contains three varieties of such terminal stages, recognized as...

Brain aromatase and the regulation of sexual activity in male mice

David C. Brooks, John S. Coon V, Cihangir M. Ercan, Xia Xu, Hongxin Dong, Jon E. Levine, Serdar E. Bulun & Hong Zhao
The biologically active estrogen, estradiol, has important roles in adult brain physiology and sexual behavior. A single gene, Cyp19a1, encodes aromatase, the enzyme that catalyzes the conversion of testosterone to estradiol in the testis and brain of male mice. Estradiol formation was shown to regulate sexual activity in various species, but the relative contributions to sexual behavior of estrogen arising in the brain versus gonads remained unclear. To determine the role of brain aromatase in...

Within-colony transmission of Microsporidian and Trypanosomatid parasites in honey bee and bumble bee colonies

Mario Pinilla-Gallego, Emma Williams, Abby Davis, Jacquelyn Fitzgerald, Scott McArt & Rebecca Irwin
Parasites are commonly cited as one of the causes of population declines for both managed and wild bees. Epidemiological models sometimes assume that increasing the proportion of infected individuals in a group should increase transmission. However, social insects exhibit behaviors and traits which can dampen the link between pathogen pressure and disease spread. Understanding patterns of parasite transmission within colonies of social bees has important implications for how to control diseases within those colonies, and...

Competition for pollination and isolation from mates differentially impact four stages of pollination in a model grassland perennial

Lea K. Richardson, M. Kate Gallagher, Tracie E. Hayes, Amanda S. Gallinat, Gretel Kiefer, Kristen Manion, Miriam Jenkins, Greg Diersen & Stuart Wagenius
1. Species that persist in small populations isolated by habitat destruction may experience reproductive failure. Self-incompatible plants face dual threats of mate-limitation and competition with co-flowering plants for pollination services. Such competition may lower pollinator visitation, increase heterospecific pollen transfer, and reduce the likelihood that a visit results in successful pollination. 2. To understand how isolation from mates and competition with co-flowering species contribute to reproductive failure in fragmented habitat, we conducted an observational study...

Supplemental materials for: Peri- and post-pubertal estrogen exposures of female mice optimize uterine responses later in life

Sylvia Hewitt, Marleny Carmona, Grace Foley, Lauren Donoghue, Sydney Lierz, Wipawee Winuthayanon & Kenneth Korach
At birth, all female mice, including those that either lack estrogen receptor α (ERα-knockout) or that express mutated forms of ERα (AF2ERKI), have a hypoplastic uterus. However, uterine growth and development that normally accompanies pubertal maturation does not occur in ERα-knockout or AF2ERKI mice, indicating ERα mediated estrogen signaling is essential for this process. Mice that lack Cyp19 (aromatase, ArKO mice), an enzyme critical for estrogen (E2) synthesis, are unable to make E2, and lack...

Data from: Temporal scale-dependence of plant-pollinator networks

Benjamin Schwarz, Diego Vázquez, Paul CaraDonna, Tiffany Knight, Gita Benadi, Carsten Dormann, Benoit Gauzens, Elena Motivans, Julian Resasco, Nico Blüthgen, Laura Burkle, Qiang Fang, Christopher Kaiser-Bunbury, Ruben Alarcón, Justin Bain, Natacha Chacoff, Shuang-Quan Huang, Gretchen LeBuhn, Molly MacLeod, Theodora Petanidou, Claus Rasmussen, Michael Simanonok, Amibeth Thompson, Daniel Cariveau, Michael Roswell … & Jochen Fründ
The study of mutualistic interaction networks has led to valuable insights into ecological and evolutionary processes. However, our understanding of network structure may depend upon the temporal scale at which we sample and analyze network data. To date, we lack a comprehensive assessment of the temporal scale-dependence of network structure across a wide range of temporal scales and geographic locations. If network structure is temporally scale-dependent, networks constructed over different temporal scales may provide very...

Data from: Persistent firing in LEC III neurons is differentially modulated by learning and aging

Carmen Lin, Venus Sherathiya, M Matthew Oh & John Disterhoft
Whether and how persistent firing in lateral entorhinal cortex layer III (LEC III) supports temporal associative learning is still unknown. In this study, persistent firing was evoked in vitro from LEC III neurons from young and aged rats that were behaviorally naïve or trained on trace eyeblink conditioning. Persistent firing ability from neurons from behaviorally naïve aged rats was lower compared to neurons from young rats. Neurons from learning impaired aged animals also exhibited reduced...

Reproductive hormones mediate changes in the gut microbiome during pregnancy and lactation in Phayre’s leaf monkeys

Elizabeth Mallott, Carola Borries, Andreas Koenig, Amy Lu & Katherine R. Amato
Studies in multiple host species have shown that gut microbial diversity and composition change during pregnancy and lactation. However, the specific mechanisms underlying these shifts are not well understood. Here, we use longitudinal data from wild Phayre’s leaf monkeys to test the hypothesis that fluctuations in reproductive hormone concentrations contribute to gut microbial shifts during pregnancy. We described the microbial taxonomic composition of 91 fecal samples from 15 females (n=16 cycling, n=36 pregnant, n=39 lactating)...

Data from: Diverse and complex muscle spindle afferent firing properties emerge from multiscale muscle mechanics

Kyle Blum, Brian Horslen, Kenneth Campbell, Brian Horslen, Paul Nardelli, Stephen Housley, Timothy Cope & Lena Ting
Despite decades of research, we lack a mechanistic framework capable of predicting how movement-related signals are transformed into the diversity of muscle spindle afferent firing patterns observed experimentally, particularly in naturalistic behaviors. Here, a biophysical model demonstrates that well-known firing characteristics of mammalian muscle spindle Ia afferents – including movement history dependence, and nonlinear scaling with muscle stretch velocity – emerge from first principles of muscle contractile mechanics. Further, mechanical interactions of the muscle spindle...

Single-chain heteropolymers transport protons selectively and rapidly

Tao Jiang, Aaron Hall, Marco Eres, Zahra Hemmatian, Baofu Qiao, Yun Zhou, Zhiyuan Ruan, Andrew D. Couse, William T. Heller, Haiyan Huang, Monica Olvera De La Cruz, Marco Rolandi & Ting Xu
Precise protein sequencing and folding are believed to generate the natural channel structure and chemical diversity of proteins, both of which are essential to synthetically achieve proton transport performance comparable to that seen in natural systems. Geometrically defined channels have been fabricated using peptides, DNAs, carbon nanotubes, sequence-defined polymers and organic frameworks; however, none of these channels rivals the performance observed in their natural counterparts. Here we show that without forming an atomically structured channel,...

Data from: Area 2 of primary somatosensory cortex encodes kinematics of the whole arm

Raeed Chowdhury, Joshua Glaser & Lee Miller
Proprioception, the sense of body position, movement, and associated forces, remains poorly understood, despite its critical role in movement. Most studies of area 2, a proprioceptive area of somatosensory cortex, have simply compared neurons' activities to the movement of the hand through space. By using motion tracking, we sought to elaborate this relationship by characterizing how area 2 activity relates to whole arm movements. We found that a whole-arm model, unlike classic models, successfully predicted...

Data from: Three-month modified Rankin Scale as a determinant of five-year cumulative costs after ischemic stroke: an analysis of 11,136 patients in Korea

Seong-Eun Kim, Heeyoung Lee, Jun Yup Kim, Keon-Joo Lee, Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Kang-Ho Choi, Joon-Tae Kim, Dong-Ick Shin, Min-Ju Yeo, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Dong-Eog Kim, Wi-Sun Ryu, Jong-Moo Park, Kyusik Kang, Jae Guk Kim, Soo Joo Lee, Mi-Sun Oh, Kyung-Ho Yu, Byung-Chul Lee, Hong-Kyun Park, Keun-Sik Hong … & Hee-Joon Bae
Objective: Stroke is a devastating and costly disease; however, there is a paucity of information on long-term costs and on how they differ according to 3-month modified Rankin scale (mRS), which is a primary outcome variable in acute stroke intervention trials. Methods: We analyzed a prospective multicenter stroke registry (Clinical Research Collaboration for Stroke in Korea) database through linkage with claims data from the National Health Insurance Service with follow up to December 2016. Healthcare...

Supplementary data 1: Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy

Kirsten McCaffery, Rachael Dodd, Erin Cvejic, Julie Ayre, Carys Batcup, Jennifer Isautier, Tessa Copp, Carissa Bonner, Kristen Pickles, Brooke Nickel, Thomas Dakin, Samuel Cornell & Michael S Wolf
Supplementary data for Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy. Box 1. Survey Items and Scoring Scale

Suplementary data 3: Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy

Kirsten McCaffery, Rachael Dodd, Erin Cvejic, Julie Ayre, Carys Batcup, Jennifer Isautier, Tessa Copp, Carissa Bonner, Kristen Pickles, Brooke Nickel, Thomas Dakin, Samuel Cornell & Michael S Wolf
Supplementary data for Disparities in COVID-19 related knowledge, attitudes, beliefs and behaviours by health literacy. COVID survey baseline form

Data from: Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes

Andrew Skol, Segun Jung, Ana Marija Sokovic, Siquan Chen, Sarah Fazal, Olukayode Sosina, Poulami Borkar, Amy Lin, Maria Sverdlov, Dingcai Cao, Anand Swaroop, Ionut Bebu, Barbara Stranger & Michael Grassi
We determined differential gene expression in response to high glucose in lymphoblastoid cell lines derived from matched individuals with type 1 diabetes with and without retinopathy. Those genes exhibiting the largest difference in glucose response were assessed for association to diabetic retinopathy in a genome-wide association study meta-analysis. Expression Quantitative Trait Loci (eQTLs) of the glucose response genes were tested for association with diabetic retinopathy. We detected an enrichment of the eQTLs from the glucose...

Spectral-power associations reflect amplitude modulation and within-frequency interactions on the sub-second timescale and cross-frequency interactions on the seconds timescale

Satoru Suzuki & Melisa Menceloglu
We investigated the global structure of intrinsic cross-frequency dynamics by systematically examining power-based temporal associations among a broad range of oscillation frequencies both within and across EEG-based current sources (sites). We focused on power-based associations that could reveal unique timescale dependence independently of interacting frequencies. Large spectral-power fluctuations across all sites occurred at two characteristic timescales, sub-second and seconds, yielding distinct patterns of cross-frequency associations. On the fast sub-second timescale, within-site (local) associations were consistently...

Registration Year

  • 2020

Resource Types

  • Dataset


  • Northwestern University
  • University of Sydney
  • University of Pittsburgh
  • North Carolina State University
  • Seoul Medical Center
  • Seoul National University Bundang Hospital
  • Chonnam National University Hospital
  • Utah State University
  • Columbia University
  • National Institute of Environmental Health Sciences