75 Works

Additional file 1 of Circulating tumor DNA integrating tissue clonality detects minimal residual disease in resectable non-small-cell lung cancer

Siwei Wang, Ming Li, Jingyuan Zhang, Peng Xing, Min Wu, Fancheng Meng, Feng Jiang, Jie Wang, Hua Bao, Jianfeng Huang, Binhui Ren, Mingfeng Yu, Ninglei Qiu, Houhuai Li, Fangliang Yuan, Zhi Zhang, Hui Jia, Xinxin Lu, Shuai Zhang, Xiaojun Wang, Youtao Xu, Wenjia Xia, Tongyan Liu, Weizhang Xu, Xinyu Xu … & Rong Yin
Additional file 1. Table S1: Patient demography.

Identification of the metabolic remodeling profile in the early-stage of myocardial ischemia and the contributory role of mitochondrion

Jun He, Qian Liu, Jie Wang, Fangjing Xu, Yucheng Fan, Ruhua He, Ru Yan & Li Zhu
Cardiac remodeling is the primary pathological feature of chronic heart failure. Prompt inhibition of remodeling in acute coronary syndrome has been a standard procedure, but the morbidity and mortality are still high. Exploring the characteristics of ischemia in much earlier stages and identifying its biomarkers are essential for introducing novel mechanisms and therapeutic strategies. Metabolic and structural remodeling of mitochondrion is identified to play key roles in ischemic heart disease. The mitochondrial metabolic features in...

Additional file 2 of Chronic constriction injury-induced changes in circular RNA expression profiling of the dorsal root ganglion in a rat model of neuropathic pain

Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu & Zhiyao Wang
Additional file 2: Table S2. List of total circRNAs detected in the DRG of NC and CCI rats. RNA-seq was performed to profile circRNA expression in four paired DRG samples. A total of 13,172 circRNAs were detected in the L4–L5 DRG samples from the CCI and NC groups (4 mice per group).

Additional file 3 of Chronic constriction injury-induced changes in circular RNA expression profiling of the dorsal root ganglion in a rat model of neuropathic pain

Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu & Zhiyao Wang
Additional file 3: Table S3. List of DEcircRNAs were identified between the CCI and NC groups. Following differential expression analysis, 374 DEcircRNAs were identified between the CCI and NC groups (4 mice per group) by using FC filtering (FC ≥ 2 or ≤ 0.5) and FDR (Q < 0.001).

Additional file 4 of Chronic constriction injury-induced changes in circular RNA expression profiling of the dorsal root ganglion in a rat model of neuropathic pain

Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu & Zhiyao Wang
Additional file 4: Table S4. List of circRNAs and miRNA predicted by using miRanda and TargetScan. Potential connections between circRNAs and microRNAs were predicted by using TargetScan and miRanda, and the interaction results were displayed by Cytoscape. All the circRNAs and miRNAs were listed.

Additional file 1 of Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer

Erbao Chen, Jing Yi, Jing Jiang, Zhilin Zou, Yuqian Mo, Qingqi Ren, Zewei Lin, Yi Lu, Jian Zhang & Jikui Liu
Additional file1: Supplementary excel 1. Detailed clinical features in the two HCC cohorts.

Additional file 3 of Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer

Erbao Chen, Jing Yi, Jing Jiang, Zhilin Zou, Yuqian Mo, Qingqi Ren, Zewei Lin, Yi Lu, Jian Zhang & Jikui Liu
Additional file3: Supplementary excel 3. The correlation analysis between FA scores and lncRNAs in the GSE76427 cohort.

TGFβ signaling activation correlates with immune-inflamed tumor microenvironment across human cancers and predicts response to immunotherapy

Jiadong Xia, Qijie Zhang, Jiaochen Luan, Pengxiang Min, Hanjie Zhang, Gang Chen, Chengjian Ji & Ninghong Song
Considering the determining role of TGFβ signaling in the tumor microenvironment (TME) on immune evasion, the inhibition of signaling is expected to enhance the therapeutic efficacy of immunotherapies, especially immune checkpoint blockade (ICB), which is confirmed in preclinical data. However, successive failures in clinical translation occur at the initial stage. To provide a better understanding of TGFβ signaling within the TME and its relation to the individual immunological status, we performed a pan-cancer analysis comparing...

The antimicrobial systems of Streptococcus suis promote niche competition in pig tonsils

Zijing Liang, Huizhen Wu, Chen Bian, Hao Chen, Yanling Shen, Xueping Gao, Jiale Ma, Huochun Yao, Liping Wang & Zongfu Wu
Streptococcus suis can cause severe infections in pigs and humans. The tonsils of pigs are major niches for S. suis, and different serotypes of S. suis can be found in the same tonsil. Pig tonsil colonization by S. suis is believed to be an important source of infection for humans and pigs. However, how S. suis competes for a stable tonsil niche is unknown. Here, we found that S. suis strain WUSS351, isolated from a...

The antimicrobial systems of Streptococcus suis promote niche competition in pig tonsils

Zijing Liang, Huizhen Wu, Chen Bian, Hao Chen, Yanling Shen, Xueping Gao, Jiale Ma, Huochun Yao, Liping Wang & Zongfu Wu
Streptococcus suis can cause severe infections in pigs and humans. The tonsils of pigs are major niches for S. suis, and different serotypes of S. suis can be found in the same tonsil. Pig tonsil colonization by S. suis is believed to be an important source of infection for humans and pigs. However, how S. suis competes for a stable tonsil niche is unknown. Here, we found that S. suis strain WUSS351, isolated from a...

INFLUENCE OF HIGH-INTENSITY INTERVAL TRAINING ON TABLE TENNIS PLAYERS

Jing Chen & Jianming Wang
ABSTRACT Introduction The development of the technical level of table tennis and the reform of the rules require players to have a proportionally comprehensive technical base, aiming to climb to the top of world table tennis. Objective Study the effect of high-intensity competition on the physical fitness of table tennis players. Methods By analyzing the questionnaires of coaches and athletes in colleges and universities in Zhejiang province, as well as the development status and situation...

Additional file 1 of Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining

Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang, Hui-Ping Lu, Dong-Ming Li, Zhi-Guang Huang, Yu-Lu Tang, Ye-Ying Fang, Yu-Xing Tang, Ya-Si Su, Wen-Bin Dai, Shang-Ling Pan, Zhen-Bo Feng, Gang Chen & Juan He
Additional file 1: Table S1. Raw data for IHC staining.

Additional file 3 of Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining

Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang, Hui-Ping Lu, Dong-Ming Li, Zhi-Guang Huang, Yu-Lu Tang, Ye-Ying Fang, Yu-Xing Tang, Ya-Si Su, Wen-Bin Dai, Shang-Ling Pan, Zhen-Bo Feng, Gang Chen & Juan He
Additional file 3: Table S3. Expression values of ZNF71 extracted from included datasets.

Additional file 3 of Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining

Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang, Hui-Ping Lu, Dong-Ming Li, Zhi-Guang Huang, Yu-Lu Tang, Ye-Ying Fang, Yu-Xing Tang, Ya-Si Su, Wen-Bin Dai, Shang-Ling Pan, Zhen-Bo Feng, Gang Chen & Juan He
Additional file 3: Table S3. Expression values of ZNF71 extracted from included datasets.

Additional file 5 of Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining

Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang, Hui-Ping Lu, Dong-Ming Li, Zhi-Guang Huang, Yu-Lu Tang, Ye-Ying Fang, Yu-Xing Tang, Ya-Si Su, Wen-Bin Dai, Shang-Ling Pan, Zhen-Bo Feng, Gang Chen & Juan He
Additional file 5: Table S5. Pearson correlation analysis between ZNF71 and its putative target genes which relates to tight junction.

Additional file 1 of CSP I-plus modified rEndostatin inhibits hepatocellular carcinoma metastasis via down-regulation of VEGFA and integrinβ1

Xueqin Chen, Yan Wang, Hancong Liu, Jingjing Zhang, Jie Wang, Xiaobao Jin & Yan Ma
Additional file 1: Supplementary Figures. The full-length blots of WB in Fig. 5B. Whole-cell extracts were resolved on 10% SDS-PAGE by bio-rad Mini-PROTEAN with 10 sample Wells (1Marker, 2space, 3Blank group, 4CSP I-plus group, 5Endostar group, 6rES-CSP group, 7rES-CSP+ heparin group, 8DDP group, 9space, 10Marker), and then electrotransferred onto a polyvinylidene difluoride (PVDF) membrane (Millipore). The membranes were then probed with respective primary antibodies against VEGFA, MMP2, integrinβ1, and E-cadherin procured from Abcam, β-actin from...

Additional file 3 of Histological and molecular responses of Vigna angularis to Uromyces vignae infection

Xiwang Ke, Jie Wang, Xiaodan Xu, Yongxia Guo, Yuhu Zuo & Lihua Yin
Supplementary Material 3

Identification of key genes and miRNA-mRNA regulatory networks associated with bone marrow immune microenvironment regulations in multiple myeloma by integrative bioinformatics analysis

Niluopaer Tuerxun, Jie Wang, Yu-ting Qin, Fang Zhao, Huan Wang, Jian-hua Qu, Md. Nazim Uddin & Jian-ping Hao
The deregulation of microRNAs (miRNAs) and genes in the bone marrow microenvironment have been involved with the pathogenesis of multiple myeloma (MM). However, the exploration of miRNA-mRNA regulatory networks in MM remains lacking. We used GSE125363, GSE125361, GSE47552, GSE2658, GSE136324, GSE16558, and GSE13591 datasets for this bioinformatics study. We identified 156 downregulated and 13 upregulated differentially expressed miRNAs (DEmiRs) in MM. The DEmiRs are associated with the enrichment of pathways mainly involved with cancers, cellular...

Additional file 1 of Circulating tumor DNA integrating tissue clonality detects minimal residual disease in resectable non-small-cell lung cancer

Siwei Wang, Ming Li, Jingyuan Zhang, Peng Xing, Min Wu, Fancheng Meng, Feng Jiang, Jie Wang, Hua Bao, Jianfeng Huang, Binhui Ren, Mingfeng Yu, Ninglei Qiu, Houhuai Li, Fangliang Yuan, Zhi Zhang, Hui Jia, Xinxin Lu, Shuai Zhang, Xiaojun Wang, Youtao Xu, Wenjia Xia, Tongyan Liu, Weizhang Xu, Xinyu Xu … & Rong Yin
Additional file 1. Table S1: Patient demography.

Cannabidiol attenuates methamphetamine-induced conditioned place preference in male rats and viability in PC12 cells through the Sigma1R/AKT/GSK3β/CREB signaling pathway

Liu Liu, Juan Li, Chan Wang, Yue Xu, Chi-Kwan Leung, Genmeng Yang, Shucheng Lin, Shuwei Zhang, Yi Tan, Huijie Zhang, Haowei Wang, Jianxing Liu, Ming Li & Xiaofeng Zeng
Background: Methamphetamine use is associated with several negative consequences, including neurotoxicity and greater probability of exhibiting a substance use disorder. Sigma1 receptor is involved in the neurobiological basis of several drug use disorders. Cannabidiol has received attention in the treatment of drug use disorders and neurotoxicity. Objectives: To investigate the effects of cannabidiol on methamphetamine-induced conditioned place preference (CPP) and the viability of PC12 cells. Methods: Adult male rats (n = 70) underwent methamphetamine (2...

Additional file 5 of Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer

Erbao Chen, Jing Yi, Jing Jiang, Zhilin Zou, Yuqian Mo, Qingqi Ren, Zewei Lin, Yi Lu, Jian Zhang & Jikui Liu
Additional file5: Supplementary excel 5. The KEGG analysis of TFs in the TCGA LIHC cohort.

Additional file 2 of Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer

Erbao Chen, Jing Yi, Jing Jiang, Zhilin Zou, Yuqian Mo, Qingqi Ren, Zewei Lin, Yi Lu, Jian Zhang & Jikui Liu
Additional file2: Supplementary excel 2. The correlation analysis between FA scores and lncRNAs in the TCGA LIHC cohort.

Additional file 4 of Chronic constriction injury-induced changes in circular RNA expression profiling of the dorsal root ganglion in a rat model of neuropathic pain

Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu & Zhiyao Wang
Additional file 4: Table S4. List of circRNAs and miRNA predicted by using miRanda and TargetScan. Potential connections between circRNAs and microRNAs were predicted by using TargetScan and miRanda, and the interaction results were displayed by Cytoscape. All the circRNAs and miRNAs were listed.

Genetic analysis of the mitochondrial DNA control region in Tai–Kadai-speaking Dong population in southwest China

Zheng Ren, Yuhang Feng, Hongling Zhang, Qiyan Wang, Meiqing Yang, Yubo Liu, Cuiyun Le, Jie Wang & Jiang Huang
Dong people in Southwest China are officially recognised as an ethnic group, but there has been a lack of population genetic research on this group, especially based on mitochondrial DNA data. To study the sequences and haplogroups of the mitochondrial DNA control region in a typical Dong population, and to provide help for the construction of a forensic mitochondrial DNA analysis reference database in East Asia. The sequences of the mitochondrial DNA control region were...

MicroRNA-218-5p affects lung adenocarcinoma progression through targeting endoplasmic reticulum oxidoreductase 1 alpha

Gang Chen, Qihao Wang & Kunyu Wang
Lung adenocarcinoma (LUAD) severely threatens the health of people owing to its lethality. Nonetheless, the underlying mechanisms on LUAD development remain unclear to a great extent. This work aimed to probe the functions of miR-218-5p in LUAD. MiR-218-5p and endoplasmic reticulum oxidoreductase 1 alpha (ERO1A) were screened as differently downregulated and upregulated RNAs in LUAD, respectively, by bioinformatics analyses. The results of cell functional assays stated that enforced expression of miR-218-5p notably restrained cell viability,...

Registration Year

  • 2022
    75

Resource Types

  • Dataset
    75

Affiliations

  • Affiliated Eye Hospital of Wenzhou Medical College
    75
  • Zhejiang University
    61
  • Sun Yat-sen University
    52
  • Shanghai Jiao Tong University
    52
  • Nanjing Medical University
    52
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    50
  • Chinese Academy of Sciences
    41
  • University of Chinese Academy of Sciences
    39
  • Stanford University
    38
  • Capital Medical University
    38