39 Works

Additional file 4 of Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

Di Cui, Xilong Cui, Xiaoliang Xu, Wenjing Zhang, Yu Yu, Yingxin Gao, Chuanzhong Mei & Weiwei Zheng
Additional file 4.

PDE12 expression data from diabetes patients and controls

Knud Josefsen, Karsten Buschard, Hasim Tekin, Lars Krogvold, Ivan Gerling & Flemming Poicot
Type 1 diabetes (T1D) incidence is increased after COVID-19 infection in children under 18 years of age. Interferon-α-activated oligoadenylate synthetase and downstream RNAseL activation degrade pathogen RNA, but can also damage host RNA when RNAseL activity is poorly regulated. One such regulator is PDE12 which degrades 2′-5′ oligoadenylate units, thereby decreasing RNAseL activity. We analyzed PDE12 expression in islets from non-diabetic donors, individuals with newly (median disease duration 35 days) and recently (5 years) diagnosed...

Improving winter wheat yield estimation under complex irrigation conditions through coupling APSIM crop growth model and the machine learning approach

Quandi Niu, Jianxi Huang, Xuecao Li, Hai Huang, Haixiang Guan, Wei Wang, Wei Su, Li Li, Shuangxi Miao & Dongqin Yin
The annual dynamics of winter wheat yield in Henan, China from 2018 to 2021 are provided, with the resolution of 20m and GeoTiff format.

Analysis of prognostic factors for cervical mucinous adenocarcinoma and establishment and validation a nomogram: a SEER-based study

Yiping Hao, Qingqing Liu, Ruowen Li, Zhonghao Mao, Nan Jiang, Bingyu Wang, Wenjing Zhang & Baoxia Cui
Up to now, there are no relevant studies on prognostic factors of cervical mucinous adenocarcinoma. Therefore, we explored the prognostic factors for cervical mucinous adenocarcinoma, and established and validated the prognostic model using the SEER database. We selected the independent factors through univariate and multivariate analyses. LASSO regression analysis was conducted to identify potential risk factors. In conjunction with LASSO and multivariate analysis, the nomogram incorporated three variables, including age, tumour size, and AJCC stage...

Additional file 1 of The distribution of bioactive gibberellins along peach annual shoots is closely associated with PpGA20ox and PpGA2ox expression profiles

Mengmeng Zhang, Yangtao Ma, Xianbo Zheng, Bin Tan, Xia Ye, Wei Wang, Langlang Zhang, Jidong Li, Zhiqian Li, Jun Cheng & Jiancan Feng
Additional file 1: Figure S1. Verification of PpKO gene structure using the alignment results of reads obtained from the transcriptome of peach flowers, stems, fruits and pits. Figure S2. Sequence alignment of GA20ox from Arabidopsis and peach. The LPWKET motif are underlined. Figure S3. The phylogenetic trees of CPS (A), KS (B), KO (C), KAO (D) and GA3ox (E). The amino acid sequences were downloaded from Phytozome database and the Gene ID are listed after...

Long non-coding RNA TRPM2 antisense RNA as a potential therapeutic target promotes tumorigenesis and metastasis in esophageal cancer

Wei Wang, Yukai Dai, Xin Yang & Xinming Xiong
Esophageal cancer (EC) is one type of aggressive gastrointestinal cancers. The treatment of EC is challenging. Effective therapeutic targets require development. Long non-coding RNA TRPM2 antisense RNA (LncRNA TRPM2-AS) is considering a novel biomarker and therapeutic target for various types of cancer. However, the role of lncRNA TRPM2-AS in EC remains unknown. This study aimed to illustrate effects of LncRNA TRPM2-AS on EC growth and metastasis and potential underlying molecular mechanisms. LncRNA TRPM2-AS expression was...

Additional file 1 of Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma

Tongyan Liu, Chencheng Han, Panqi Fang, Zhifei Ma, Xiaoxiao Wang, Hao Chen, Siwei Wang, Fanchen Meng, Cheng Wang, Erbao Zhang, Guozhang Dong, Hongyu Zhu, Wenda Yin, Jie Wang, Xianglin Zuo, Mantang Qiu, Jinke Wang, Xu Qian, Hongbing Shen, Lin Xu, Zhibin Hu & Rong Yin
Additional file 1. Supplementary Tables.

Improving winter wheat yield estimation under complex irrigation conditions through coupling APSIM crop growth model and the machine learning approach

Quandi Niu, Jianxi Huang, Xuecao Li, Hai Huang, Haixiang Guan, Wei Wang, Wei Su, Li Li, Shuangxi Miao & Dongqin Yin
The annual dynamics of winter wheat yield in Henan, China from 2018 to 2021 are provided, with the resolution of 20m and GeoTiff format.

Additional file 3 of Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

Di Cui, Xilong Cui, Xiaoliang Xu, Wenjing Zhang, Yu Yu, Yingxin Gao, Chuanzhong Mei & Weiwei Zheng
Additional file 3.

Additional file 4 of Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

Di Cui, Xilong Cui, Xiaoliang Xu, Wenjing Zhang, Yu Yu, Yingxin Gao, Chuanzhong Mei & Weiwei Zheng
Additional file 4.

Set2 family regulates mycotoxin metabolism and virulence via H3K36 methylation in pathogenic fungus Aspergillus flavus

Zhenhong Zhuang, Xiaohua Pan, Mengjuan Zhang, Yaju Liu, Chuanzhong Huang, Yu Li, Ling Hao & Shihua Wang
Aspergillus flavus infects various crops with aflatoxins, and leads to aspergillosis opportunistically. Though H3K36 methylation plays an important role in fungal toxin metabolism and virulence, no data about the biological function of H3K36 methylation in A. flavus virulence has been reported. Our study showed that the Set2 histone methyltransferase family, AshA and SetB, involves in morphogenesis and mycotoxin anabolism by regulating related transcriptional factors, and they are important for fungal virulence to crops and animals....

A potential novel inflammation biomarker for predicting the prognosis of decompensated liver cirrhosis

Yanan Xie, Chiyi He & Wei Wang
This study aimed to explore the prognostic value of the lymphocyte (LYM)-to-white blood cell (WBC) ratio (LWR) in patients with decompensated liver cirrhosis (DLC). This study was conducted by recruiting 214 patients with DLC with different aetiologies (development cohort). Receiver operating characteristic (ROC) curve analyses were used to assess the predictive accuracy of the LWR, and Youden’s index was used to determine the optimal cut-off values of the LWR based on the ROC curve. Next,...

Additional file 2 of The landscape of hervRNAs transcribed from human endogenous retroviruses across human body sites

Jianqi She, Minghao Du, Zhanzhan Xu, Yueqi Jin, Yu Li, Daoning Zhang, Changyu Tao, Jian Chen, Jiadong Wang & Ence Yang
Additional file 2: Table S1-S15. Supplementary tables.

SOMAS

Peiyuan Gao, Amity Andersen, Jonathan Sepulveda, Gihan Panapitiya, Aaron Hollas, Emily Saldanha, Vijayakumar Murugesan & Wei Wang
SOMAS dataset and XYZ files

Additional file 1 of Association between serum homocysteine and sarcopenia among hospitalized older Chinese adults: a cross-sectional study

Bing Lu, Lingyu Shen, Haiqiong Zhu, Ling Xi, Wei Wang & Xiaojun Ouyang
Additional file 1: Excel 1. Raw data.

m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2

Wei Wang, Ying He, Lu-Lu Zhai, Long-Jiang Chen, Li-Chao Yao, Lun Wu, Zhi-Gang Tang & Jin-Zhuo Ning
Pancreatic cancer (PC) is one of the most fatal cancers with a very poor prognosis. Here, we found that N6-methyladenosine (m6A) RNA demethylase fat mass and obesity-related protein (FTO) promote the growth, migration and invasion of PC. FTO expression level is increased in human PC and is associated with poor prognosis of PC patients. Knockdown of FTO increases m6A methylation of TFPI-2 mRNA in PC cells, thereby increasing mRNA stability via the m6A reader YTHDF1,...

m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2

Wei Wang, Ying He, Lu-Lu Zhai, Long-Jiang Chen, Li-Chao Yao, Lun Wu, Zhi-Gang Tang & Jin-Zhuo Ning
Pancreatic cancer (PC) is one of the most fatal cancers with a very poor prognosis. Here, we found that N6-methyladenosine (m6A) RNA demethylase fat mass and obesity-related protein (FTO) promote the growth, migration and invasion of PC. FTO expression level is increased in human PC and is associated with poor prognosis of PC patients. Knockdown of FTO increases m6A methylation of TFPI-2 mRNA in PC cells, thereby increasing mRNA stability via the m6A reader YTHDF1,...

Additional file 1 of Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility

Sara Kress, Claudia Wigmann, Qi Zhao, Christian Herder, Michael J. Abramson, Holger Schwender & Tamara Schikowski
Additional file 1. Air pollution assignment within the European Study of Cohorts for Air Pollution Effects. Details of air pollution measurements. Genotyping, quality control and imputation. Details of genotyping, quality control and imputation.

Additional file 1 of Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility

Sara Kress, Claudia Wigmann, Qi Zhao, Christian Herder, Michael J. Abramson, Holger Schwender & Tamara Schikowski
Additional file 1. Air pollution assignment within the European Study of Cohorts for Air Pollution Effects. Details of air pollution measurements. Genotyping, quality control and imputation. Details of genotyping, quality control and imputation.

Set2 family regulates mycotoxin metabolism and virulence via H3K36 methylation in pathogenic fungus Aspergillus flavus

Zhenhong Zhuang, Xiaohua Pan, Mengjuan Zhang, Yaju Liu, Chuanzhong Huang, Yu Li, Ling Hao & Shihua Wang
Aspergillus flavus infects various crops with aflatoxins, and leads to aspergillosis opportunistically. Though H3K36 methylation plays an important role in fungal toxin metabolism and virulence, no data about the biological function of H3K36 methylation in A. flavus virulence has been reported. Our study showed that the Set2 histone methyltransferase family, AshA and SetB, involves in morphogenesis and mycotoxin anabolism by regulating related transcriptional factors, and they are important for fungal virulence to crops and animals....

Additional file 5 of Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

Di Cui, Xilong Cui, Xiaoliang Xu, Wenjing Zhang, Yu Yu, Yingxin Gao, Chuanzhong Mei & Weiwei Zheng
Additional file 5.

Salidroside induced repair of myocardial infarction through Nrf2/HO-1

Yanbo Fan, Wei Wang, Liqun Tian & Jie Yin
Abstract Salidroside (SAL) has been confirmed to have some protective effects against inflammatory injury. However, little information was established as to the mechanism of these protective effects. To this effect, we designed this study to explore the protective effects and mechanisms of SAL against myocardial infarction (MI). A rat MI model was established and divided into five groups (n = 6): sham, MI, MI+SAL, MI+ LY294002 (PI3K inhibitor), and MI+SAL+ LY294002. The cardiac function and...

SOMAS

Peiyuan Gao, Amity Andersen, Jonathan Sepulveda, Gihan Panapitiya, Aaron Hollas, Emily Saldanha, Vijayakumar Murugesan & Wei Wang
SOMAS dataset and XYZ files

Additional file 1 of Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma

Tongyan Liu, Chencheng Han, Panqi Fang, Zhifei Ma, Xiaoxiao Wang, Hao Chen, Siwei Wang, Fanchen Meng, Cheng Wang, Erbao Zhang, Guozhang Dong, Hongyu Zhu, Wenda Yin, Jie Wang, Xianglin Zuo, Mantang Qiu, Jinke Wang, Xu Qian, Hongbing Shen, Lin Xu, Zhibin Hu & Rong Yin
Additional file 1. Supplementary Tables.

Additional file 5 of Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

Di Cui, Xilong Cui, Xiaoliang Xu, Wenjing Zhang, Yu Yu, Yingxin Gao, Chuanzhong Mei & Weiwei Zheng
Additional file 5.

Registration Year

  • 2022
    39

Resource Types

  • Dataset
    39

Affiliations

  • University of Tennessee Health Science Center
    39
  • Fudan University
    35
  • Sun Yat-sen University
    27
  • University of Science and Technology of China
    27
  • Huazhong University of Science and Technology
    25
  • Sichuan University
    23
  • Capital Medical University
    23
  • North West Agriculture and Forestry University
    21
  • Fudan University Shanghai Cancer Center
    21
  • Wenzhou Medical University
    21