Additional file 1: Table S1. Gene list of Onco-LymScan panel. Table S2. Overview of patient characteristics. Table S3. Demographic of patient characteristics. Table S4. Sequencing quality data of tumor gDNA samples. Table S5. Sequencing quality data of cfDNA samples. Table S6. Univariate Cox proportional hazard regression survival analysis including pretreatment ctDNA levels and other clinical indices.

Near-infrared-II (NIR-II) fluorescence imaging has rapidly developed for the noninvasive investigation of physiological and pathological activities in living organisms with high spatiotemporal resolution. However, the penetration depth of fluorescence restricts its ability to provide deep anatomical information. Scientists integrate NIR-II fluorescence imaging with other imaging modes (such as photoacoustic and magnetic resonance imaging) to create multimodal imaging that can acquire detailed anatomical and quantitative information with deeper penetration by using multifunctional probes. This review offers...

Near-infrared-II (NIR-II) fluorescence imaging has rapidly developed for the noninvasive investigation of physiological and pathological activities in living organisms with high spatiotemporal resolution. However, the penetration depth of fluorescence restricts its ability to provide deep anatomical information. Scientists integrate NIR-II fluorescence imaging with other imaging modes (such as photoacoustic and magnetic resonance imaging) to create multimodal imaging that can acquire detailed anatomical and quantitative information with deeper penetration by using multifunctional probes. This review offers...

Additional file 1: Supplementary Figures. The full-length blots of WB in Fig. 5B. Whole-cell extracts were resolved on 10% SDS-PAGE by bio-rad Mini-PROTEAN with 10 sample Wells (1Marker, 2space, 3Blank group, 4CSP I-plus group, 5Endostar group, 6rES-CSP group, 7rES-CSP+ heparin group, 8DDP group, 9space, 10Marker), and then electrotransferred onto a polyvinylidene difluoride (PVDF) membrane (Millipore). The membranes were then probed with respective primary antibodies against VEGFA, MMP2, integrinβ1, and E-cadherin procured from Abcam, β-actin from...

Extracellular matrix (ECM), as an important framework for tumor microenvironment, plays important roles in many critical processes, including tumor growth, invasion, immune suppression, and drug resistance. However, few biomarkers of ECM-related genes (ERGs) have been developed for prognosis prediction and clinical treatment of bladder cancer (BC) patients. Bioinformatics analysis and LC-MS/MS analysis were used to screen differentially expressed ERGs in BC. Multivariate Cox regression analysis and Lasso regression analysis were used to construct and validate...

Additional file 2: Supplemental Table 2. Clinicopathological data of 159 paraffin-embedded NPC tissues and 29 non-neoplastic nasopharyngeal epithelialtissues for in situhybridization.

Additional file 6: Supplemental Table 6. The potential β-TrCP-interacting proteins in CNE2 cells identified by LC-MS/MS spectrometry after pull-down with β-TrCP antibody.

Additional file 9: Supplemental Table 9. Clinicopathologicaldata of 30 paraffin-embedded NPC tissues for immunohistochemistry (IHC) and in situ hybridization (ISH).

Additional file 6: Fig S6. Standard Plot for ALA measurement. x: the absorbance at 554 nm; y: ALA concentration of sample after diluted (mg/L).

Additional file 3. The direct transcripts of the executed search strategies about CAD and psoriasis.

Additional file 4. The direct transcripts of the executed search strategies about MI and psoriasis.

Additional file 10: Table S9. The number of different types of hydrogenase and sulfide quinone oxidoreductase (sqr) in microbial genomes.

Additional file 10: Table S9. The number of different types of hydrogenase and sulfide quinone oxidoreductase (sqr) in microbial genomes.

Additional file 11: Table S10. Distributions of selected key enzymes in microbial genomes.

Additional file 11: Table S10. Distributions of selected key enzymes in microbial genomes.

Additional file 2: Table S1. Genome statistics for MAGs.

Additional file 3: Table S2. Summary of the metagenome sequencing statistics.

Additional file 4: Table S3. Features and functional gene counts of metagenomic data sets from geothermal systems used for comparison analysis.

Additional file 4: Table S3. Features and functional gene counts of metagenomic data sets from geothermal systems used for comparison analysis.

Additional file 9: Table S8. Genomic and proteomic data of the predominant Nautiliaceae and Thiomicrorhabdus MAGs used for metabolic modules reconstruction.

Additional file 9: Table S8. Genomic and proteomic data of the predominant Nautiliaceae and Thiomicrorhabdus MAGs used for metabolic modules reconstruction.

Additional file 1.

The annual N fertilizers use dataset in China at 5 km × 5 km resolution covering the period of 1952 to 2018. Unit: g N m-2 yr-1. Format: ENVI/IDL data file format.

The incidence of cervical cancer ranks third among all female tumours globally and second in developing countries. However, the role of eukaryotic translation initiation factor 3 subunit D (EIF3D) in cervical carcinoma is unknown. This study investigated the effects of EIF3D on cell progression of cervical carcinoma and its underlying mechanism in vivo and vitro models. There were increases of EIF3D expression mRNA and protein expression levels in patients with cervical carcinoma. Disease-free survival (DFS)...

The incidence of cervical cancer ranks third among all female tumours globally and second in developing countries. However, the role of eukaryotic translation initiation factor 3 subunit D (EIF3D) in cervical carcinoma is unknown. This study investigated the effects of EIF3D on cell progression of cervical carcinoma and its underlying mechanism in vivo and vitro models. There were increases of EIF3D expression mRNA and protein expression levels in patients with cervical carcinoma. Disease-free survival (DFS)...