Additional file 2. Transcriptome sequencing identified 346 differentially expressed genes for MM cells transfected with sh-HNRNPA2B1-8226 and the control sh-NC-8226.

Additional file 2. Transcriptome sequencing identified 346 differentially expressed genes for MM cells transfected with sh-HNRNPA2B1-8226 and the control sh-NC-8226.

Additional file 3. MeRIP sequencing identified 496 differentially peaks for MM cells transfected with sh-HNRNPA2B1-8226 and the control sh-NC-8226.

Table S1

Additional File 1: Supplementary Table S1

Additional file 3: Table S3. The classification, annotation and GO functional categorization of the PgMYB gene transcripts.

Additional file 3: Table S3. The classification, annotation and GO functional categorization of the PgMYB gene transcripts.

Phytosulfokines (PSKs) are a class of tyrosine-sulfated pentapeptides. PSK-α, PSK-γ, and PSK-δ are three reported PSK members involved in regulating plant growth, development, and resistance to biotic and abiotic stresses. Here, we reported a novel type of PSK, PSK-ε with the sequence YSO3VYSO3TN, and its precursor proteins (MtPSKε, LjPSKε, and GmPSKε), specifically from legume species. PSK-ε peptide differs from PSK-δ by one amino acid and is close to PSK-δ in the phylogenetic relationship. Expression profile...

Phytosulfokines (PSKs) are a class of tyrosine-sulfated pentapeptides. PSK-α, PSK-γ, and PSK-δ are three reported PSK members involved in regulating plant growth, development, and resistance to biotic and abiotic stresses. Here, we reported a novel type of PSK, PSK-ε with the sequence YSO3VYSO3TN, and its precursor proteins (MtPSKε, LjPSKε, and GmPSKε), specifically from legume species. PSK-ε peptide differs from PSK-δ by one amino acid and is close to PSK-δ in the phylogenetic relationship. Expression profile...

Additional file 14: Supplementary Table 2. The results of expression differences for pan-cancer analysis.

Additional file 14: Supplementary Table 2. The results of expression differences for pan-cancer analysis.

Additional file 1: Table S1. 26_lactate_metabolism_related_genes.

Additional file 1: Table S1. 26_lactate_metabolism_related_genes.

Additional file 3: Raw documents and tables in the process of data analysis.

Adipogenesis involves complex interactions between transcription and metabolic signalling. Exploration of the developmental characteristics of intramuscular adipocyte will provide targets for enhancing beef cattle marbling without increasing obesity. Few reports have compared bovine perirenal and intramuscular adipocyte transcriptomes using the combined analysis of transcriptomes and lipid metabolism to explore differences in adipogenic characteristics. We identified perirenal preadipocytes (PRA) and intramuscular preadipocytes (IMA) in Qinchuan cattle. We found that IMA were highly prolific in the early...

The epidemiological features of the newly emerged carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) and its potential threat to human health are currently unknown. In this study, a total of 784 blaKPC-2-bearing CRKP strains collected from three hospitals located at different geographical locales in China during 2014–2017 were subjected to molecular typing, screening of virulence plasmid, string test and WGS (367/784 strains). The proportion of CRKP among all clinical K. pneumoniae strains increased sharply in China during...

Whether combined CsA with androgen therapy was superior to androgen therapy alone in NSAA remains controversial. This study aimed to assess the efficacy and safety of combined therapy versus androgen therapy for NSAA patients using a meta-analytic approach. An electronic database of PubMed, EmBase, Cochrane library, CNKI, VIP, and Wanfang was systematically searched for randomized controlled trials (RCTs) from their inception to February 2020. The primary endpoint was effective rate, while the secondary endpoints included...

Extracellular trap (ET) appears as a double-edged sword for the host since it participates in host immune defense by entrapping pathogens, while excessive ET release also contributes to various diseases progression including atherosclerosis, cancer, and autoimmune disorders. A better understanding of ET formation and regulation will be beneficial for developing strategies for infection control and ET-associated disease treatment. There is some evidence indicating that prior infection can enhance extracellular killing. Neutrophils from cancer or sepsis...

Considering the determining role of TGFβ signaling in the tumor microenvironment (TME) on immune evasion, the inhibition of signaling is expected to enhance the therapeutic efficacy of immunotherapies, especially immune checkpoint blockade (ICB), which is confirmed in preclinical data. However, successive failures in clinical translation occur at the initial stage. To provide a better understanding of TGFβ signaling within the TME and its relation to the individual immunological status, we performed a pan-cancer analysis comparing...

Staphylococcus aureus can survive within phagocytes. Indeed, we confirm in this study that approximately 10% of population persists in macrophages during S. aureus infection, while the rest are eliminated due to bacteriolysis, which is of particular interest to us. Herein, we observe that the bacteriolysis is an early event accompanied by macrophage death during S. aureus infection. Furthermore, the cell death is significantly accelerated following increased intracellular bacteriolysis, indicating that intracellular bacteriolysis induces cell death....

This dataset contains all of the data underlying the figures in the accompanying paper "New Model-Free Daily Inversion of NOx Emissions using TROPOMI (MCMFE-NOx) and its Uncertainty: Deducing a See-Saw of Halved Well Regulated Sources and Doubled New Sources". These are listed respectively under: Coefficients.zip Figure3.zip Figure4.zip Figure5.zip Figure6.zip Figure7.zip Figure8.zip Figure9.zip Figure10.zip All data is provided as .nc files, and all plots are provided as .png files. All emissions are provided as a part...

Bounded rationality includes potential cognitive deficits that limit human rational behaviour. In this paper, we allow for estimation errors of their utility and consider bounded rationality in queueing models with retrials. Upon arrival, customers decide whether to join the system based on their perceived utility, and their choice behaviour is characterised by a logit choice model. For a revenue-seeking server and a social planner, we investigate corresponding optimal pricing strategies. We find that the revenue-optimal...

Plant-specific TCP transcription factors play an essential role in plant growth and development. They can regulate leaf curvature, flower symmetry and the synthesis of secondary metabolites. The flavonoids in Ginkgo biloba leaf are one of the main medicinally bioactivate compounds, which have pharmacological and beneficial health effects for humans. In this study, a total of 13 TCP genes were identified in G. biloba, and 5 of them belonged to PCF subclades (GbTCP03, GbTCP07, GbTCP05, GbTCP13,...

Additional file 2: Table S3. CRs genetic interactions related to drug response in cancers.

Additional file 1. On the orininal data of the study.