Additional file 2: Additional Tables 1-5.

Additional file 7: Table S5. The information of the seven candidates.

Additional file 6. Prognosis model constructed by AC005154.6/hsa-miR-29c-3p/CCNL2 axis.

Additional file 3: Supplemental Table 1. Overview of 24-hour Urinary Protein in the Included SRs and MAs. Supplemental Table 2. Overview of the Included SRs and MAs of Renal Function. Supplemental Table 3. Overview of the Included SRs and MAs about the Outcome of Serum Albumin. Supplemental Table 4. Overview of the Included SRs and MAs of AL. Supplemental Table 5. Overview of the included SRs and MAs about the outcomes of WBC. Supplemental Table...

Additional file 4. Table S3. Correlation between protein and mRNA levels of 9 candidate genes.

Age-related macular degeneration (AMD), the leading cause of blindness among the elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) cell heterogeneity is a well-recognized but understudied pathogenic factor. Due to the daily phagocytosis of photoreceptor outer segments, unique photo-oxidative stress, and high metabolism for maintaining vision, the RPE has robust macroautophagy/autophagy, and mitochondrial and antioxidant networks. However, the autophagy subtype, mitophagy, in the RPE and AMD is understudied. Here, we found...

The remnant Comei igneous province in SE Tibet has been recognized as a product of early Kerguelen mantle plume activity. In this paper, we investigate mafic dykes and sills intruded into Lakang Formation in the southeastern Tethyan Himalaya. Based on new whole-rock geochemical, Sr-Nd-Pb isotopic and SHRIMP zircon U-Pb geochronological data, these rocks can be divided into three groups. Group 1 is composed of OIB-like mafic dykes and sills with lower εNd(t) (+1.78-+2.55) and dated...

Age-related macular degeneration (AMD), the leading cause of blindness among the elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) cell heterogeneity is a well-recognized but understudied pathogenic factor. Due to the daily phagocytosis of photoreceptor outer segments, unique photo-oxidative stress, and high metabolism for maintaining vision, the RPE has robust macroautophagy/autophagy, and mitochondrial and antioxidant networks. However, the autophagy subtype, mitophagy, in the RPE and AMD is understudied. Here, we found...

The aim of the present study was to investigate the injuries of spleen and intestinal immune system induced by 2 Gy 60Co γ ray in mice. A total of 120 Balb/c mice were randomly divided into two groups: blank control (Ctrl) and model (IR). The IR mice were exposed to a single dose of total body irradiation (2 Gy, dose rate: 1 Gy/min) and sacrificed on 1st, 3rd, 7th, 14th and 21st day after irradiation....

Additional file 3: Table S3. Codon usage and relative synonymous codon usage (RSCU) values of protain-coding genes of the 16 Sorbus s.s. chloroplast genomes

Additional file 6: Table S6. The nucleotide variability (Pi) of 16 Sorbus s.s. chloroplast genomes

Additional file 7. Drugs significantly associated with the expression of CCNL2.

Additional file 8. Twenty-nine small molecules identified from CMap.

Additional file 1. Supplementary Tables.

Describe symptoms before and at time of register-diagnosis in children and adolescents. A random sample was selected for chart-review from a Danish nationwide cohort of patients <18 years registered with an incident ICD-10 register-diagnosis of single hypomanic/manic episode or bipolar disorder between 1995 and 2014. Patients with symptoms which adequately documented a BD diagnosis in the chart were included for analysis. 521 were diagnosed in the study period. A random sample of 25% were selected,...

Global land cover has undergone extensive and rapid changes as a result of human activities and climate change. These changes have had a significant impact on biodiversity, the surface energy balance, and sustainable development. Global land cover data underpins research on the development of earth system models, resource management, and evaluation of the ecological environment. However, there are limitations in the classification detail, spatial resolution, and rapid change monitoring capability of global land cover change...

Macrophages (ΜΦs) are important immune effector cells that promote (M1 ΜΦs) or inhibit (M2 ΜΦs) inflammation and are involved in numerous physiological and pathogenic immune responses. Their precise role and relevance, however, are not fully understood for lack of non-invasive quantification methods. Here, we show that two-photon excited fluorescence lifetime imaging (TPE-FLIM), a label-free non-invasive method, can visualize ΜΦs in the human dermis in vivo. We demonstrate in vitro that human dermal ΜΦs exhibit specific...

Additional file 2: Table S1. Reports all gene names and corresponding number of alterations, including SNV, gene expression outliers, indels and gene fusions that were identified in the cohort. Table S2. Lists the genetic alterations that were identified as predictive biomarkers and corresponding treatment options per patient by Heidelberg (HD) and Berlin (BLN) MTBs. Results from a second sequencing for the same patient are indicated by a comma. Table S3. Provides information on treatment options...

Additional file 2: Table S1. Reports all gene names and corresponding number of alterations, including SNV, gene expression outliers, indels and gene fusions that were identified in the cohort. Table S2. Lists the genetic alterations that were identified as predictive biomarkers and corresponding treatment options per patient by Heidelberg (HD) and Berlin (BLN) MTBs. Results from a second sequencing for the same patient are indicated by a comma. Table S3. Provides information on treatment options...

Additional file 5. Table S4. The immunoreactive scores of GATA3, TRPS1 and MGP in 1201 cases of breast cancer.

Additional file 3: Table S1 Analysis of variance for LL, LW and LA in an F1 population using mixed model for two years in two locations (CP and LF)

Additional file 5: Table S3. List of 2,061 up-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 6: Table S4. List of 1,709 down-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 6: Table S4. List of 1,709 down-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 7: Table S5. The information of the seven candidates.