Data from: The effect of sitagliptin on carotid artery atherosclerosis in Type 2 Diabetes: the PROLOGUE randomized controlled trial

Jun-Ichi Oyama, Koichi Node, Atsushi Tanaka, Toyoaki Murohara, Masafumi Kitakaze, Tomoko Ishizu, Yasunori Sato, Haruo Kamiya, Masaharu Ishihara, Koji Maemura, Hirofumi Tomiyama, Yukihito Higashi, Hirotsugu Yamada, Kentaro Yamashita, Yasuko K. Bando, Shinichiro Ueda & Teruo Inoue
Background: Experimental studies have suggested that dipeptidyl peptidase-4 (DPP-4) inhibitors provide cardiovascular protective effects. We performed a randomized study to evaluate the effects of sitagliptin added on to the conventional therapy compared with conventional therapy alone (diet, exercise, and/or drugs, except for incretin-related agents) on the intima-media thickness (IMT) of the carotid artery, a surrogate marker for the evaluation of atherosclerotic cardiovascular disease, in people with type 2 diabetes mellitus (T2DM). Methods and Findings: We...

Registration Year

  • 2016
    1

Resource Types

  • Dataset
    1

Affiliations

  • Hyogo College of Medicine
    1
  • Tokyo Medical University
    1
  • Chiba University
    1
  • National Cerebral and Cardiovascular Center
    1
  • Tokushima University Hospital
    1
  • University of Tsukuba
    1
  • University of the Ryukyus
    1
  • Japanese Red Cross Nagoya Daiichi Hospital
    1
  • National Hospital Organization
    1
  • Hiroshima University
    1