130 Works

miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes

Xiaoqiong Tan, Tingting Zhu, Linqiang Zhang, Lin Fu, Ying Hu, Huiqin Li, Chengbin Li, Jingjing Zhang, Bin Liang & Jing Liu
Obesity is a major global health issue that contributes to the occurrence of metabolic disorders. Based on this fact, understanding the underlying mechanisms and to uncover promising therapeutic approaches for obesity have attracted intense investigation. Brown adipose tissue (BAT) can help burns excess calories. Therefore, promoting White adipose tissue (WAT) browning and BAT activation is an attractive strategy for obesity treatment. MicroRNAs (miRNAs) are small, non-coding RNAs, which are involved in regulation of adipogenic processes...

Additional file 2 of Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination

Wei Zhang, Yan Yang, Liewen Lin, Jingquan He, Jingjing Dong, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Fanna Liu & Yong Dai
Additional file 2. Table S1. Ubiquitination annotation. Table S2. Protein annotation. Table S3. 42 proteins having ten or more than ten ubiquitination modifications. Table S4. 20 ubiquitin-binding motifs. Table S5. 2242 proteins with an upregulated ubiquitination and 1204 proteins with a down-regulated ubiquitination. Table S6. 1172 up-regulated proteins and 1700 down-regulated proteins. Table S7. 646 Secretory proteins. Table S8. 53 proteins having an upregulated expression simultaneously with a down-regulated ubiquitination and 116 proteins having down-regulated...

L18_sample_liver2

shizhe yu, Haoren Wang, Lingpeng Yang, Yingxue Yan, Qiang Cai, Duo Ma, Jian Zhao, Long Jiang, Zehai Gao, Zhiyong Yu & Zongping Xia
Processed data compression package for sample L18(sample2).This contains the downstream files after the spaceranger process.

L18_sample_liver2

shizhe yu, Haoren Wang, Lingpeng Yang, Yingxue Yan, Qiang Cai, Duo Ma, Jian Zhao, Long Jiang, Zehai Gao, Zhiyong Yu & Zongping Xia
Processed data compression package for sample L18(sample2).This contains the downstream files after the spaceranger process.

Additional file 4 of A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology

Yongqun He, Hong Yu, Anthony Huffman, Asiyah Yu Lin, Darren A. Natale, John Beverley, Ling Zheng, Yehoshua Perl, Zhigang Wang, Yingtong Liu, Edison Ong, Yang Wang, Philip Huang, Long Tran, Jinyang Du, Zalan Shah, Easheta Shah, Roshan Desai, Hsin-hui Huang, Yujia Tian, Eric Merrell, William D. Duncan, Sivaram Arabandi, Lynn M. Schriml, Jie Zheng … & Barry Smith
Additional file 4: Supplemental Table 3. Protein Ontology representation of SARS-CoV-2 proteins. Comparative information in RefSeq and UniProtKB is also provided.

Additional file 3 of Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Xin Zhao, Yubing Hu, Yan Zhao, Lin Wang, Zifang Wu, Myat Thu Soe, Myat Phone Kyaw, Liwang Cui, Xiaotong Zhu & Yaming Cao
Additional file 3: Table S3. Codon-based tests for selection on Pvs230 in China–Myanmar border and Myanmar isolates.

Nitrogen fertilizers use in China from 1952 to 2018

Zhen Yu, Jing Liu & GIRI KATTEL
The annual N fertilizers use dataset in China at 5 km × 5 km resolution covering the period of 1952 to 2018. Unit: g N m-2 yr-1. Format: ENVI/IDL data file format.

Construction of a High-Density Genetic Linkage Map and QTL Analysis of Fiber Yield Traits in Kenaf (Hibiscus Cannabinus L.) via SLAF-seq

Meixia Chen, Yi Xu, Siyuan Chen, Chengkang Zhang, Hui Shi, Ting Liu, Jiantang Xu, Jianmin Qi & Liwu Zhang
High-density genetic maps are vital for quantitative trait loci (QTL) mapping, genome assembly, and marker-assisted selection (MAS) in plants. Meanwhile, kenaf (Hibiscus cannabinus L.) is an important crop that produces raw fiber to many industries. However, both high-density genetic map construction and QTL identification have been limited in this crop due to insufficient molecular markers. Here, we constructed a high-density genetic linkage map in kenaf via specific-locus amplified fragment sequencing (SLAF-seq). An F7:8 mapping population...

Additional file 1 of Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China

Jing Liu, Zirong Li, Ting Lu, Junping Pan, Li Li, Yanwen Song, Dan Hu, Yanhong Zhuo, Ying Chen & Qin Xu
Additional file 1: Table S1. Gene mutations in the TCGA cohort.

The data for the manuscript \"Combining paleomagnetic and Re–Os isotope data to date hydrocarbon generation and accumulation processes\"

Yong Zhang, Dong Jia, Jing Hu & Adrian R. Muxworthy
The manuscript "Combining paleomagnetic and Re–Os isotope data to date hydrocarbon generation and accumulation processes" is submitted to the journal JGR, and the data here were used to support the viewpoints in the manuscript. This dataset include paleomagnetic, rock magnetic and geochemical data, which were present in one excle file and four word files.

Additional file 9 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 9: Table S4. The number of DMCs (CpG, CHG and CHH) in different genetic regions.

Additional file 9 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 9: Table S4. The number of DMCs (CpG, CHG and CHH) in different genetic regions.

Additional file 15 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 15: Table S10. The genome-wide correlation between DNA methylation and gene expression and list of MetGDE genes.

Additional file 15 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 15: Table S10. The genome-wide correlation between DNA methylation and gene expression and list of MetGDE genes.

Additional file 16 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 16: Table S11. The results of functional enrichment differentially methylated and expressed genes (MetGDE genes).

Additional file 1 of Expanding known viral diversity in plants: virome of 161 species alongside an ancient canal

Shixing Yang, Qingqing Mao, Yan Wang, Jingxian He, Jie Yang, Xu Chen, Yuqing Xiao, Yumin He, Min Zhao, Juan Lu, Zijun Yang, Ziyuan Dai, Qi Liu, Yuxin Yao, Xiang Lu, Hong Li, Rui Zhou, Jian Zeng, Wang Li, Chenglin Zhou, Xiaochun Wang, Quan Shen, Hui Xu, Xutao Deng, Eric Delwart … & Wen Zhang
Additional file 1. Table S1: Plant species and library information.

Additional file 20 of Gut microbiota is associated with the effect of photoperiod on seasonal breeding in male Brandt’s voles (Lasiopodomys brandtii)

Hanyi Zhu, Guoliang Li, Jing Liu, Xiaoming Xu & Zhibin Zhang
Additional file 20. Photoperiod experiment and FMT experiment_data.

LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway

Yue Li, Jian Zhao, Weijie Zhang, Anqi Wang, Min Jiao, Xin Cai, Jianjie Zhu, Zeyi Liu & Jian-an Huang
Long non-coding RNAs (LncRNA) play important roles in multiple types of cancers. We addressed the role of LINC02535 by regulating the miR-30a-5p /GalNAc Transferase 3 (GALNT3) axis to promote the proliferation, migration, and invasion in lung adenocarcinoma (LUAD) cells. The Cancer Genome Atlas (TCGA) database screened differentially expressed lncRNAs. Quantitative real-time PCR analysis (qRT-PCR) confirmed that LINC02535 is highly expressed in LUAD tissues and cells. In vitro experiments showed that LINC02535 promotes the proliferation, migration,...

Additional file 2 of mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A

Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Additional file 2: Table S1. Detected gene levels upon methionine restriction in livers of HCC mouce models.

Additional file 1 of Transcriptome analysis of intestine from alk-SMase knockout mice reveals the effect of alk-SMase

Jiang Zhu, Lingqi Wang, Zhongwu Guo, Tao Zhang & Ping Zhang
Additional file 1. The list of differentially expressed genes

Additional file 10 of Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis

Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard & Eveline M. Ibeagha-Awemu
Additional file 10: Table S5. The list of DMRs and annotation.

lipidomics raw data for CaV2.3

Xia Yao, Yan Wang, Zhifei Wang, Xiao Fan, Di Wu, Jian Huang, Alexander Mueller, Sarah Gao, Miaohui Hu, Carol V. Robinson, Yong Yu, Shuai Gao & Nieng Yan
ZIP archive containing raw LC-MS data of CaV2.3

Additional file 2 of ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells

Zijie Gao, Jianye Xu, Yang Fan, Zongpu Zhang, Huizhi Wang, Mingyu Qian, Ping Zhang, Lin Deng, Jie Shen, Hao Xue, Rongrong Zhao, Teng Zhou, Xing Guo & Gang Li
Additional file 2: Table S1. Correlation analysis of ARPC1B with PN and MES marker genes (Correlation). Table S2. Mass spectrometry result of proteins related with ARPC1B. Table S3. The correlation between the ARPC1B expression and drug sensitivity assessed by Spearman algorithm (correlation).

Circ_0004904 suppresses trophoblast cell proliferation, invasion and migration in preeclampsia via upregulating the expression of DNA damage inducible alpha by interacting with miR-19a-3p

Zhenhao Chu, Yang Wang, Shuo Zhang & Pin Cao
Preeclampsia (PE) is the most common complication in the pregnancy of women. PE progression was found to be associated with dysregulated circular RNAs (circRNAs), and we aimed to explore the pathological mechanism with circ_0004904 in PE. The circ_0004904, microRNA-19a-3p (miR-19a-3p) and DNA damage inducible alpha (GADD45A) were quantified via reverse transcription-quantitative polymerase chain reaction assay. Trophoblast cell behaviors were examined by cell viability using Cell Counting Kit-8 assay, cell proliferation using EdU assay, cell apoptosis...

Protection of intestinal immune barrier against ischemia/reperfusion injury in a swine model using anisodamine hydrobromide

Guijuan Dong, Jun Yang, Xin Zhao & Shubin Guo
Abstract Intestinal ischemia/reperfusion (I/R) causes barrier impairment and bacterial influx. This study explored the protective effects of anisodamine hydrobromide (AH) on intestinal I/R injury caused by cardiopulmonary resuscitation (CPR) after cardiac arrest (CA). After successful CPR, minipigs were randomly divided into two groups (n = 8): saline and AH (4 mg/kg), and then treated with saline or AH via central venous injection, respectively. The same procedures without ventricular fibrillation initiation were conducted in the Sham...

Registration Year

  • 2022
    130

Resource Types

  • Dataset
    130

Affiliations

  • Third Hospital of Hebei Medical University
    130
  • Shanghai Jiao Tong University
    111
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    108
  • Zhejiang University
    92
  • Capital Medical University
    85
  • University of Chinese Academy of Sciences
    81
  • Sichuan University
    79
  • First Affiliated Hospital of Soochow University
    74
  • Soochow University
    68
  • Fudan University
    67