22 Works

Additional file 2 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 2: Table S1. Statistical analysis of behavioural bioassays. Two-way ANONA method was used to evaluate the significance of the behavioural modifications.

Data from: Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis

Laura Grogan, Jason Mulvenna, Joel P. A. Gummer, Benjamin C. Scheele, Lee Berger, Scott D. Cashins, Michael S. McFadden, Peter Harlow, David A. Hunter, Robert D. Trengove & Lee F. Skerratt
PLEASE NOTE, THESE DATA ARE ALSO REFERRED TO IN ANOTHER PUBLICATION. PLEASE SEE http://dx.doi.org/10.1111/mec.14493. The fungal skin disease chytridiomycosis has caused the devastating decline and extinction of hundreds of amphibian species globally, yet the potential for evolving resistance, and the underlying pathophysiological mechanisms remain poorly understood. We exposed 406 naïve, captive-raised alpine tree frogs (Litoria verreauxii alpina) from multiple populations (one evolutionarily naïve to chytridiomycosis) to the aetiological agent Batrachochytrium dendrobatidis in two concurrent and...

Data from: Less is more: extreme genome complexity reduction with ddRAD using Ion Torrent semiconductor technology

Lilian Pukk, Freed Ahmad, Shihab Hasan, Veljo Kisand, Riho Gross & Anti Vasemägi
Massively parallel sequencing a small proportion of the whole genome at high coverage enables answering a wide range of questions from molecular evolution and evolutionary biology to animal and plant breeding and forensics. In this study, we describe the development of restriction-site associated DNA (RAD) sequencing approach for Ion Torrent PGM platform. Our protocol results in extreme genome complexity reduction using two rare-cutting restriction enzymes and strict size selection of the library allowing sequencing of...

Additional file 1 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

Data from: Reconfiguration of functional brain networks and metabolic cost converge during task performance

Andreas Hahn, Michael Breakspear, Lucas Rischka, Wolfgang Wadsak, Godber Godbersen, Verena Pichler, Paul Michenthaler, Thomas Vanicek, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberger & Luca Cocchi
The ability to solve cognitive tasks depends upon adaptive changes in the organization of whole-brain functional networks. However, the link between task-induced network reconfigurations and their underlying energy demands is poorly understood. We address this by multimodal network analyses integrating functional and molecular neuroimaging acquired concurrently during a complex cognitive task. Task engagement elicited a marked increase in the association between glucose consumption and functional brain network reorganization. This convergence between metabolic and neural processes...

Additional file 1 of Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk

Shannon D’Urso, Pooja Arumugam, Therese Weider, Liang-Dar Hwang, Tom A. Bond, John P. Kemp, Nicole M. Warrington, David M. Evans, Tracy A. O’Mara & Gunn-Helen Moen
Additional file 1: Table S1. Genome-wide significant independent SNPs for Body Mass Index in women (Pulit 2018). Table S2. Genome-wide significant independent SNPs for Years Ovulating (Hg19). Table S3. Genome-wide significant independent SNPs for age at menarche downloaded from the ReproGen Consortium Website (Perry et al., 2014; Hg19). Table S4. Genome-wide significant independent SNPs for age at menopause downloaded from the ReproGen Consortium Website (Hg19; Day et al., 2015). Table S5. Genome-wide significant independent SNPs...

Additional file 3 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 3: Table S2. A list of the total proteins, unique proteins and corresponding peptides identified in naïve B. glabrata with reference to the B. glabrata proteome.

A randomized clinical trial to compare P. falciparum gametocytaemia and infectivity following blood-stage or mosquito bite induced controlled malaria infection

Teun Bousema, Manon Alkema, Isaie Reuling, Gerdie De Jong, Kjerstin Lanke, Luc Coffeng, Geert-Jan Van Gemert, Marga Van De Vegte-Bolmer, Quirijn De Mast, Reinout Van Crevel, Christian Ockenhouse, Karen Ivinson, James McCarthy, Robert Sauerwein & Katharine Collins
For malaria elimination efforts, it is important to better understand parasite transmission to mosquitoes and to develop models to allow early clinical evaluation of transmission-blocking interventions. We previously described a Controlled Human Malaria Infection protocol for induction of gametocytemia in malaria naïve volunteers by mosquito bite (CHMI-trans) (Reuling et al., 2018). Here, we compared gametocyte production and infectivity in the CHMI-trans model after bites of Plasmodium falciparum (Pf)- infected mosquitoes to that after intravenous administration...

Additional file 8 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 8: Table S5. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata SCW with reference to the S. mansoni proteome, and enriched GO terms related to the proteins.

Additional file 5 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 5: Table S4. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata with reference to the B. glabrata proteome.

Additional file 9 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 9: Table S6. The results of PPIs shown in Fig. 5 and the co-expression data export from STRING to support the PPI of S. mansoni proteins.

Additional file 1 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

Additional file 1 of Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk

Shannon D’Urso, Pooja Arumugam, Therese Weider, Liang-Dar Hwang, Tom A. Bond, John P. Kemp, Nicole M. Warrington, David M. Evans, Tracy A. O’Mara & Gunn-Helen Moen
Additional file 1: Table S1. Genome-wide significant independent SNPs for Body Mass Index in women (Pulit 2018). Table S2. Genome-wide significant independent SNPs for Years Ovulating (Hg19). Table S3. Genome-wide significant independent SNPs for age at menarche downloaded from the ReproGen Consortium Website (Perry et al., 2014; Hg19). Table S4. Genome-wide significant independent SNPs for age at menopause downloaded from the ReproGen Consortium Website (Hg19; Day et al., 2015). Table S5. Genome-wide significant independent SNPs...

Data from: Levels of 8-oxodG predict hepatobiliary-pathology in Opisthorchis viverrini endemic settings in Thailand

Prasert Saichua, Anna Yakovleva, Christine Kamamia, Amar R. Jariwala, Jiraporn Sithithaworn, Banchop Sripa, Paul J. Brindley, Thewarach Laha, Eimorn Mairiang, Chawalit Pairojkul, Narong Khuntikeo, Jason P. Mulvenna, Paiboon Sithithaworn, Jeffrey Michael Bethony, Banchob Sripa & Jason Mulvenna
Opisthorchis viverrini is distinct among helminth infections as it drives a chronic inflammatory response in the intrahepatic bile duct that progresses from advanced periductal fibrosis (APF) to cholangiocarcinoma (CCA). Extensive research shows that oxidative stress (OS) plays a critical role in the transition from chronic O. viverrini infection to CCA. OS also results in the excision of a modified DNA lesion (8-oxodG) into urine, the levels of which can be detected by immunoassay. Herein, we...

Additional file 2 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 2: Table S1. Statistical analysis of behavioural bioassays. Two-way ANONA method was used to evaluate the significance of the behavioural modifications.

Data from: Impact of an ivermectin mass drug administration on scabies prevalence in a remote Australian Aboriginal community

Therese M. Kearns, Linda Ward, Deborah C. Holt, Bart J. Currie, Roslyn Gundjirryirr, Leanne Bundhala, Mark Chatfield, Ross M. Andrews, Richard Speare, Allen C. Cheng, James McCarthy, Jonathan R. Carapetis & Jennifer Shield
Background: Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. We report the outcomes against scabies of two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community. Methods: Utilizing a before and after study design, we measured scabies prevalence through population census with sequential MDAs at baseline and month 12. Surveys at months 6 and...

Data from: Partitioning of genetic variation across the genome using multimarker methods in a wild bird population

Matthew R. Robinson, Anna W. Santure, Isabelle DeCauwer, Ben C. Sheldon & Jon Slate
The underlying basis of genetic variation in quantitative traits, in terms of the number of causal variants and the size of their effects, is largely unknown in natural populations. The expectation is that complex quantitative trait variation is attributable to many, possibly interacting, causal variants, whose effects may depend upon the sex, age and the environment in which they are expressed. A recently developed methodology in animal breeding derives a value of relatedness among individuals...

Additional file 8 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 8: Table S5. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata SCW with reference to the S. mansoni proteome, and enriched GO terms related to the proteins.

Data from: A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

Isaie J. Reuling, Lisanne A Van De Schans, Luc E Coffeng, Kjerstin Lanke, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan Van Gemert, Karina Teelen, Rianne Siebelink-Stoter, Marga Van De Vegte-Bolmer, Quirijn De Mast, André J Van Der Ven, Karen Ivinson, Cornelus C Hermsen, Sake De Vlas, John Bradley, Katharine A Collins, Christian F Ockenhouse, James McCarthy, Robert W. Sauerwein & Teun Bousema
Background: Malaria elimination strategies require a thorough understanding of parasite transmission from human to mosquito. A clinical model to induce gametocytes to understand their dynamics and evaluate transmission-blocking interventions (TBI) is currently unavailable. Here, we explore the use of the well-established Controlled Human Malaria Infection model (CHMI) to induce gametocyte carriage with different antimalarial drug regimens. Methods: In a single centre, open-label randomised trial, healthy malaria-naive participants (aged 18–35 years) were infected with Plasmodium falciparum...

Underlying data for 'Rapid molecular assays for the detection of the four dengue viruses in infected mosquitoes'

Joanne Macdonald, Madeeha Ahmed, Nina Pollak, Andrew Van Den Hurk, Leon Hugo & Jody Hobson-Peters
The pantropic emergence of severe dengue disease can partly be attributed to the co-circulation of different dengue viruses (DENVs) in the same geographical location. Effective monitoring for circulation of each of the four DENVs is critical to inform disease mitigation strategies. In low resource settings, this can be effectively achieved by utilizing inexpensive, rapid, sensitive and specific assays to detect viruses in mosquito populations. In this study, we developed four rapid DENV tests with direct...

Additional file 3 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 3: Table S2. A list of the total proteins, unique proteins and corresponding peptides identified in naïve B. glabrata with reference to the B. glabrata proteome.

Additional file 4 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 4: Table S3. A list of the total proteins, unique proteins and corresponding peptides identified resistant B. glabrata with reference to the B. glabrata proteome.

Registration Year

  • 2022
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Resource Types

  • Dataset
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Affiliations

  • QIMR Berghofer Medical Research Institute
    22
  • University of the Sunshine Coast
    12
  • Southern Medical University
    11
  • Hohai University
    11
  • Shandong University
    11
  • Shanghai Jiao Tong University
    11
  • Virginia Commonwealth University
    11
  • Northeast Forestry University
    11
  • Chinese Academy of Sciences
    11
  • Jiangsu University
    11