7 Works

m6A RNA methylation regulators were associated with the malignancy and prognosis of ovarian cancer

Cheng Zhang, JinHui Liu, Hongyu Guo, Dandan Hong, Jing Ji, Qin Zhang, Qun Guan & Qingling Ren
N6-methyladenosine (m6A) RNA methylation regulators play a regulatory role in tumor pathogenesis and development. However, the role of m6A regulator genes in ovarian cancer (OC) has not been fully elucidated. This study aims to investigate the mRNA expressions, clinicopathological features, and prognostic values of m6A regulators in OC. Here, we demonstrate that the 17 m6A RNA methylation regulators are differentially expressed in ovarian cancer and normal tissues. By using consensus clustering, all ovarian cancer patients...

Uncovering ceRNA integrated networks that associate with fertility in a photoperiod and temperature sensitive male sterile wheat line

Jian-fang Bai, Hao-yu Guo, Shao-hua Yuan, Ting-ting Li, Wen-jing Duan, Zi-han Liu, Yan-mei Li, Tian-bao Zhang, Feng-ting Zhang, Xiang-zheng Liao, Chang-ping Zhao & Li-ping Zhang
The pollen fertility of photoperiod/temperature sensitive genic male sterile (P/TGMS) wheat is controlled by light and/or temperature. Circular RNA (circRNA) and long non-coding RNA (lncRNA) are known to participate in the development of anthers in plants, but their impact on male sterility in the P/TGMS line is not well understood. In this study, we carried out high-throughput sequencing to investigate the differential expression of lncRNAs and circRNAs and their biological functions in anthers of photo-thermosensitive...

Micro-CT data from: Maternal care in mid-Cretaceous lagonomegopid spiders

Xiangbo Guo, Paul Selden & Dong Ren
This dataset contains the raw Micro-CT data and a 3D CT reconstruction of a piece of Burmese amber CNU009432 from "Guo, X., Selden, P. and Ren, D. (2021) Maternal care in mid-Cretaceous lagonomegopid spiders. Proc. R. Soc. B.". These data shows the maternal care behaviour of an adult female lagonomegopid spider guarding her egg sac. Maternal care benefits the survival and fitness of offspring often at a cost to the mother's future reproduction and has...

Covariance-Based Sample Selection for Heterogeneous Data: Applications to Gene Expression and Autism Risk Gene Detection

Kevin Z. Lin, Han Liu & Kathryn Roeder
Risk for autism can be influenced by genetic mutations in hundreds of genes. Based on findings showing that genes with highly correlated gene expressions are functionally interrelated, “guilt by association” methods such as DAWN have been developed to identify these autism risk genes. Previous research analyzes the BrainSpan dataset, which contains gene expression of brain tissues from varying regions and developmental periods. Since the spatiotemporal properties of brain tissue are known to affect the gene...

Data from: Ovipositor and mouthparts in a fossil insect support a novel ecological role for early orthopterans in 300 million years old forests

Lu Chen, Alexander Blanke, Jun-Jie Gu, Qiang Yang, Dong Ren & Olivier Béthoux
A high portion of the earliest known, Pennsylvanian, insect fauna is composed of the so-called ‘lobeattid insects’, which systematic affinities and role as foliage feeders remain debated. We investigated hundreds of samples of a new lobeattid species from the Xiaheyan locality using a combination of photographic techniques, including Reflectance Transforming Imaging, and geometric morphometrics, to document its morphology, and infer its phylogenetic position and ecological role. Ctenoptilus frequens sp. nov. possessed a sword-shaped ovipositor whose...

m6A RNA methylation regulators were associated with the malignancy and prognosis of ovarian cancer

Cheng Zhang, JinHui Liu, Hongyu Guo, Dandan Hong, Jing Ji, Qin Zhang, Qun Guan & Qingling Ren
N6-methyladenosine (m6A) RNA methylation regulators play a regulatory role in tumor pathogenesis and development. However, the role of m6A regulator genes in ovarian cancer (OC) has not been fully elucidated. This study aims to investigate the mRNA expressions, clinicopathological features, and prognostic values of m6A regulators in OC. Here, we demonstrate that the 17 m6A RNA methylation regulators are differentially expressed in ovarian cancer and normal tissues. By using consensus clustering, all ovarian cancer patients...

Uncovering ceRNA integrated networks that associate with fertility in a photoperiod and temperature sensitive male sterile wheat line

Jian-fang Bai, Hao-yu Guo, Shao-hua Yuan, Ting-ting Li, Wen-jing Duan, Zi-han Liu, Yan-mei Li, Tian-bao Zhang, Feng-ting Zhang, Xiang-zheng Liao, Chang-ping Zhao & Li-ping Zhang
The pollen fertility of photoperiod/temperature sensitive genic male sterile (P/TGMS) wheat is controlled by light and/or temperature. Circular RNA (circRNA) and long non-coding RNA (lncRNA) are known to participate in the development of anthers in plants, but their impact on male sterility in the P/TGMS line is not well understood. In this study, we carried out high-throughput sequencing to investigate the differential expression of lncRNAs and circRNAs and their biological functions in anthers of photo-thermosensitive...

Registration Year

  • 2021
    7

Resource Types

  • Dataset
    7

Affiliations

  • Capital Normal University
    7
  • Fudan University
    3
  • Shanghai Jiao Tong University
    3
  • Zhongshan Hospital
    3
  • Sun Yat-sen University
    2
  • West China Hospital of Sichuan University
    2
  • Zhejiang University
    2
  • Peking University Cancer Hospital
    2
  • Huazhong University of Science and Technology
    2
  • Simcere Pharmaceutical (China)
    2