2 Works

Data from: Progression of neuronal damage in an in vitro model of the ischemic penumbra

Joost Le Feber, Stelina Tzafi Pavlidou, Niels Erkamp, Michel J. A. M. Van Putten & Jeannette Hofmeijer
Improvement of neuronal recovery in the ischemic penumbra around a brain infarct has a large potential to advance clinical recovery of patients with acute ischemic stroke. However, pathophysiological mechanisms leading to either recovery or secondary damage in the penumbra are not completely understood. We studied neuronal dynamics in a model system of the penumbra consisting of networks of cultured cortical neurons exposed to controlled levels and durations of hypoxia. Short periods of hypoxia (pO2≈20mmHg) reduced...

Data from: Deformability assessment of waterborne protozoa using a microfluidic-enabled force microscopy probe

John S. McGrath, Jos Quist, James R. T. Seddon, Stanley C. S. Lai, Serge G. Lemay & Helen L. Bridle
Many modern filtration technologies are incapable of the complete removal of Cryptosporidium oocysts from drinking-water. Consequently, Cryptosporidium-contaminated drinking-water supplies can severely implicate both water utilities and consumers. Existing methods for the detection of Cryptosporidium in drinking-water do not discern between non-pathogenic and pathogenic species, nor between viable and non-viable oocysts. Using FluidFM, a novel force spectroscopy method employing microchannelled cantilevers for single-cell level manipulation, we assessed the size and deformability properties of two species of...

Registration Year

  • 2016
    2

Resource Types

  • Dataset
    2

Affiliations

  • University of Twente
    2
  • Heriot-Watt University
    1