5 Works

Founder effects shape linkage disequilibrium and genomic diversity of a partially clonal invader

Ben Flanagan, Stacy Krueger-Hadfield, Courtney Murren, Chris Nice, Allan Strand & Erik Sotka
Genomic variation of an invasive species may be affected by complex demographic histories and evolutionary changes during invasions. Here, we describe the relative influence of bottlenecks, clonality, and population expansion in determining genomic variability of the widespread red macroalga Agarophyton vermiculophyllum. Its introduction from mainland Japan to the estuaries of North America and Europe coincided with shifts from predominantly sexual to partially clonal reproduction and rapid adaptive evolution. A survey of 62,285 SNPs for 351...

Data from: An international, multi-stakeholder survey about metadata awareness, knowledge, and use in scholarly communications

Laura Paglione, Kathryn Kaiser, Michelle Urberg, Maria Johnsson, Jennifer Kemp & Alice Meadows
The Metadata 2020 initiative is an ongoing effort to bring various scholarly communications stakeholder groups together to promote principles and standards of practice to improve the quality of metadata. To understand the perspectives and practices of the main stakeholder groups (librarians, publishers, researchers and repository managers) regarding metadata, the Metadata 2020 Researcher Communications Project Group conducted a survey in the summer of 2019. The survey content was generated by representatives from the stakeholder groups who...

Supplement to: Sex and race differences in the risk of ischemic stroke associated with fasting blood glucose in REGARDS

Tracy Madsen, D. Leann Long, April P. Carson, George Howard, Dawn O. Kleindorfer, Karen L. Furie, JoAnn E. Manson, Simin Liu & Virginia J. Howard
Background: To investigate sex and race differences in the association between fasting blood glucose (FBG) and risk of ischemic stroke (IS). Methods: This prospective longitudinal cohort study included adults age ≥45 years at baseline in the Reasons for Geographic And Racial Differences in Stroke Study, followed for a median of 11.4 years. The exposure was baseline FBG (mg/dL); suspected IS events were ascertained by phone every 6 months and were physician-adjudicated. Cox proportional hazards were...

Market forces determine the distribution of a leaky function in a simple microbial community

Jeffrey Morris, Sarah Adkins-Jablonsky, Colleen Clark, Matthew Kuhl & Spiridon Papoulis
Many biological functions are leaky, and organisms that perform them contribute some of their products to a community "marketplace" where non-performing individuals may compete for them. Leaky functions are partitioned unequally in microbial communities, and the evolutionary forces determining which species perform them and which become beneficiaries are poorly understood. Here we demonstrate that the market principle of comparative advantage determines the distribution of a leaky antibiotic resistance gene in an environment occupied by two...

Discovery proteomics by mass spectrometry comparing secreted proteins from young and old mouse lung mesenchymal stromal cells

Diptiman Chanda, Victor Thannickal & James Mobley
Lung mesenchymal stromal cells (L-MSCs) were isolated from the young ( 3 months) and old (22-24 months) mice (N = 4 each) following collagenase digestion of the lungs and anchorage-dependent growth. Culture media was collected from young and old L-MSCs (10^6 cells) grown in culture for 24 hrs in serum-free condition. Culture media was then centrifuged to remove any cellular debris. Five (5) ml of supernatants were concentrated using 3kDa Molecular weight cut-off filters, and...

Registration Year

  • 2021

Resource Types

  • Dataset


  • University of Alabama at Birmingham
  • College of Charleston
  • University of Michigan-Ann Arbor
  • Lund University
  • University of Tennessee at Knoxville
  • Crossref
  • National Information Standards Organization
  • University of Southern California
  • Brigham and Women's Hospital
  • Tulane University