7 Works

Data from: The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement: methods for arriving at consensus and developing reporting guidelines

Stuart G. Nicholls, Pauline Quach, Erik Von Elm, Astrid Guttmann, David Moher, Irene Petersen, Henrik T. Sørensen, Liam Smeeth, Sinéad M. Langan & Eric I. Benchimol
Objective: Routinely collected health data, collected for administrative and clinical purposes, without specific a priori research questions, are increasingly used for observational, comparative effectiveness, health services research, and clinical trials. The rapid evolution and availability of routinely collected data for research has brought to light specific issues not addressed by existing reporting guidelines. The aim of the present project was to determine the priorities of stakeholders in order to guide the development of the REporting...

Data from: Temperature and population density determine reservoir regions of spatial persistence in highland malaria

Amir S. Siraj, Menno J. Bouma, Mauricio Santos-Vega, Asnakew K. Yeshiwondim, Dale S. Rothman, Damtew Yadeta, Paul C. Sutton & Mercedes Pascual
A better understanding of malaria persistence in highly seasonal environments such as highlands and desert fringes requires identifying the factors behind the spatial reservoir of the pathogen in the low season. In these ‘unstable’ malaria regions, such reservoirs play a critical role by allowing persistence during the low transmission season and therefore, between seasonal outbreaks. In the highlands of East Africa, the most populated epidemic regions in Africa, temperature is expected to be intimately connected...

Data from: Assessment of markers of antimalarial drug resistance in Plasmodium falciparum isolates from pregnant women in Lagos, Nigeria

Chimere Obiora Agomo, Wellington Aghoghovwia Oyibo, Colin J. Sutherland, Rachel Hallet & Mary Oguike
Background: The use of antimalarial drugs for prevention and treatment is a major strategy in the prevention of malaria in pregnancy. Although sulphadoxine-pyrimethamine (SP) is currently recommended for intermittent preventive treatment of malaria during pregnancy in Nigeria, previously used drugs for prophylaxis such as chloroquine (CQ) and pyrimethamine are accessible as they are purchased over the counter. This study describes the markers of absence or presence of resistance to quinoline (Pfcrt and Pfmdr 1) and...

Data from: Ecological host fitting of Trypanosoma cruzi TcI in Bolivia: mosaic population structure, hybridization and a role for humans in Andean parasite dispersal

Louisa A. Messenger, Lineth Garcia, Mathieu Vanhove, Carlos Huaranca, Marinely Bustamante, Marycruz Torrico, Faustino Torrico, Michael A. Miles & Martin S. Llewellyn
An improved understanding of how a parasite species exploits its genetic repertoire to colonize novel hosts and environmental niches is crucial to establish the epidemiological risk associated with emergent pathogenic genotypes. Trypanosoma cruzi, a genetically heterogeneous, multi-host zoonosis, provides an ideal system to examine the sylvatic diversification of parasitic protozoa. In Bolivia, T. cruzi I, the oldest and most widespread genetic lineage, is pervasive across a range of ecological clines. High-resolution nuclear (26 loci) and...

Data from: Association between probable postnatal depression and increased infant mortality and morbidity: findings from the DON population-based cohort study in rural Ghana

Benedict Weobong, Augustinus H. A. Ten Asbroek, Seyi Soremekun, Lu Gram, Seeba Amenga-Etego, Samuel Danso, Seth Owusu-Agyei, Martin Prince & Betty R. Kirkwood
Objectives: To assess the impact of probable depression in the immediate postnatal period on subsequent infant mortality and morbidity. Design: Cohort study nested within 4 weekly surveillance of all women of reproductive age to identify pregnancies and collect data on births and deaths. Setting: Rural/periurban communities within the Kintampo Health Research Centre study area of the Brong-Ahafo Region of Ghana. Participants: 16 560 mothers who had a live singleton birth reported between 24 March 2008...

Data from: The topology of a discussion: the #occupy case

Floriana Gargiulo, Jacopo Bindi & Andrea Apolloni
Introduction: We analyse a large sample of the Twitter activity that developed around the social movement 'Occupy Wall Street', to study the complex interactions between the human communication activity and the semantic content of a debate. Methods: We use a network approach based on the analysis of the bipartite graph @Users-#Hashtags and of its projections: the 'semantic network', whose nodes are hashtags, and the 'users interest network', whose nodes are users. In the first instance,...

Data from: Seasonal influenza vaccination delivery through community pharmacists in England: evaluation of the London pilot

Katherine Atkins, Albert Jan Van Hoek, Conall Watson, Marc Baguelin, Lethiwe Choga, Anika Patel, Thara Raj, Mark Jit & Ulla Griffiths
Objective: To evaluate the effectiveness and cost of the pan-London pharmacy initiative, a programme that allows administration of seasonal influenza vaccination to eligible patients at pharmacies. Design: We analysed 2013–15 data on vaccination uptake in pharmacies via the Sonar reporting system, and the total vaccination uptake via 2011–15 ImmForm GP reporting system data. We conducted an online survey of London pharmacists who participate in the programme to assess time use data, vaccine choice, investment costs,...

Registration Year

  • 2015

Resource Types

  • Dataset


  • London School of Hygiene & Tropical Medicine
  • Polytechnic University of Turin
  • Universidad Mayor
  • Public Health England
  • University of Lausanne
  • Aarhus University
  • King's College London
  • University of Chicago
  • University College London
  • National Health Service