4 Works

Identification and verification of vascular cell adhesion protein 1 as an immune-related hub gene associated with the tubulointerstitial injury in diabetic kidney disease

Yan Jia, Hui Xu, Qi Yu, Lishan Tan & Zuying Xiong
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD), but the pathogenesis is not completely understood. Tubulointerstitial injury plays critical roles in the development and progression of DKD. The present study aimed to investigate the profile of tubulointerstitial immune cell infiltration and reveal the underlying mechanisms between tubular cell injury and interstitial inflammation in DKD using bioinformatics strategies. First, xCell analysis identified immune cells displaying significant...

Identification and verification of vascular cell adhesion protein 1 as an immune-related hub gene associated with the tubulointerstitial injury in diabetic kidney disease

Yan Jia, Hui Xu, Qi Yu, Lishan Tan & Zuying Xiong
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD), but the pathogenesis is not completely understood. Tubulointerstitial injury plays critical roles in the development and progression of DKD. The present study aimed to investigate the profile of tubulointerstitial immune cell infiltration and reveal the underlying mechanisms between tubular cell injury and interstitial inflammation in DKD using bioinformatics strategies. First, xCell analysis identified immune cells displaying significant...

Multianalyte Sensing of Addictive Over-the-Counter (OTC) Drugs

Tsuyoshi Minami, Nina A. Esipenko, Ali Akdeniz, Ben Zhang, Lyle Isaacs & Pavel Anzenbacher
A supramolecular sensor array composed of two fluorescent cucurbit[n]uril-type receptors (probe 1 and probe 2) displaying complementary selectivities was tested for its ability to detect and quantify drug-related amines. The fluorimetric titration of the individual probes showed highly variable and cross-reactive analyte-dependent changes in fluorescence. An excellent ability to recognize a variety of analytes was demonstrated in qualitative as well as quantitative assays. Importantly, a successful quantitative analysis of several analytes of interest was achieved...

Identification and verification of vascular cell adhesion protein 1 as an immune-related hub gene associated with the tubulointerstitial injury in diabetic kidney disease

Yan Jia, Hui Xu, Qi Yu, Lishan Tan & Zuying Xiong
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD), but the pathogenesis is not completely understood. Tubulointerstitial injury plays critical roles in the development and progression of DKD. The present study aimed to investigate the profile of tubulointerstitial immune cell infiltration and reveal the underlying mechanisms between tubular cell injury and interstitial inflammation in DKD using bioinformatics strategies. First, xCell analysis identified immune cells displaying significant...

Registration Year

  • 2021
    4

Resource Types

  • Dataset
    4

Affiliations

  • Bowling Green State University
    4
  • Henan University
    3
  • Sichuan University
    3
  • Capital Medical University
    3
  • Ministry of Education of the People's Republic of China
    3
  • Yantai University
    3
  • Shanghai Jiao Tong University
    3
  • Huazhong Agricultural University
    3
  • Affiliated Hospital of Jiangsu University
    3
  • Dali University
    3