151 Works

Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways

Jun Zhao, Boyu Pan, Xinglu Zhou, Chunnuan Wu, Fengcheng Hao, Jie Zhang & Liren Liu
Osteosarcoma (OS), the most prevalent bone malignancy, mainly affects children and adolescents. Despite recent advances in multimodal therapy, the overall survival rate for OS patients remains poor. Chinese herb medicine (CHM) is an alternative therapeutic option for multifaceted diseases such as malignant tumors. For centuries in China, polygonum cuspidatum, a classic CHM, has been used to treat several diseases, nevertheless, the mechanisms underlying its therapeutic effects have not been fully elucidated. Through network pharmacology and...

Establishment of a subcutaneous adipogenesis model and distinct roles of LKB1 regulation on adipocyte lipid accumulation in high-altitude Bos grunniens

Yongqi Yue, Yonglin Hua, Jing Zhang, Yu Guo, Dan Zhao, Wentao Huo, Yan Xiong, Fenfen Chen, Yaqiu Lin, Xianrong Xiong & Jian Li
The domestic yak was regarded as a valuable model to explore the molecular mechanism of high-altitude animal adaptation, including the extreme tolerance of starvation and cold stress, which is closely associated with specifically seasonal deposition and metabolism of subcutaneous adipose tissue. However, the key regulators for these processes remain largely unknown. Here, the yak adipogenesis model in vitro was established and liver kinase b1 (LKB1) was regarded as a key negative regulator involved in yak...

Table S5.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S2.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S6.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Efficacy and safety of neoadjuvant therapy for triple-negative breast cancer: a Bayesian network meta-analysis

Yushuai Yu, Jie Zhang, Yuxiang Lin, Shaohong Kang, Xinyin Lv & Chuangui Song
Numerous studies have concentrated on neoadjuvant therapies for treating triple-negative breast cancer (TNBC) that improve the pathological complete response (pCR) rate but remain controversial. We conducted a network meta-analysis (NMA) to objectively explore the efficacy and safety of different neoadjuvant regimens. Phase II/III randomized clinical trials that compared different neoadjuvant therapies for TNBC were included. NMA and pairwise meta-analysis were performed using WinBUGS (version 1.4.3) and Review Manager 5.3. Forty-four studies with 8459 patients met...

Table S4.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Additional file 2 of Genome-wide screening for differentially methylated long noncoding RNAs identifies LIFR-AS1 as an epigenetically regulated lncRNA that inhibits the progression of colorectal cancer

Peng Song, Ying Li, Feng Wang, Lingxiao Pu, Linsen Bao, Hengfei Gao, Chuandong Zhu, Meng Wang & Liang Tao
Additional file 2: Table S1. The characteristics of methylation-driven lncRNAs.

Additional file 4 of Functional structure analysis and genome-wide identification of CNX gene family in cotton

Nan Xu, Hong Zhang, Yuexin Zhang, Yapeng Fan, Jing Wang, Waqar Afzal Malik, Cun Rui, Mingge Han, Xuke Lu, Xiugui Chen, Junjuan Wang, Delong Wang, Shuai Wang, Chao Chen, Lixue Guo, Lanjie Zhao & Wuwei Ye
Additional file 4. Table S4: ID and protein sequences of 60 CNXs family members in cotton.

Additional file 4 of Functional structure analysis and genome-wide identification of CNX gene family in cotton

Nan Xu, Hong Zhang, Yuexin Zhang, Yapeng Fan, Jing Wang, Waqar Afzal Malik, Cun Rui, Mingge Han, Xuke Lu, Xiugui Chen, Junjuan Wang, Delong Wang, Shuai Wang, Chao Chen, Lixue Guo, Lanjie Zhao & Wuwei Ye
Additional file 4. Table S4: ID and protein sequences of 60 CNXs family members in cotton.

Additional file 8 of Functional structure analysis and genome-wide identification of CNX gene family in cotton

Nan Xu, Hong Zhang, Yuexin Zhang, Yapeng Fan, Jing Wang, Waqar Afzal Malik, Cun Rui, Mingge Han, Xuke Lu, Xiugui Chen, Junjuan Wang, Delong Wang, Shuai Wang, Chao Chen, Lixue Guo, Lanjie Zhao & Wuwei Ye
Additional file 8. Table S8: Relative expression levels of 8 selected genes under four abiotic stresses.

Additional file 6 of Candidate genes screening based on phenotypic observation and transcriptome analysis for double flower of Prunus mume

Huanhuan Zhu, Yan Shi, Junwei Zhang, Manzhu Bao & Jie Zhang
Additional file 6.

Improving winter wheat yield estimation under complex irrigation conditions through coupling APSIM crop growth model and the machine learning approach

Quandi Niu, Jianxi Huang, Xuecao Li, Hai Huang, Haixiang Guan, Wei Wang, Wei Su, Li Li, Shuangxi Miao & Dongqin Yin
The annual dynamics of winter wheat yield in Henan, China from 2018 to 2021 are provided, with the resolution of 20m and GeoTiff format.

Additional file 7 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 7. G2M_checkpoint and E2F_Targets are not in the Top 20 gene sets enriched in EBP group vs Ctrl.

Additional file 7 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 7. G2M_checkpoint and E2F_Targets are not in the Top 20 gene sets enriched in EBP group vs Ctrl.

Additional file 8 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 8. 31 genes significantly regulated between EBP and EB.

Additional file 9 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 9. 386 EB-regulated genes also regulated by progesterone compared between EB and EBP.

Additional file 8 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 8. 31 genes significantly regulated between EBP and EB.

Additional file 3 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 3. 807 Common genes between estrogen-regulated in the OVX WT and dysregulated in the AF_FFF GD3.

Additional file 4 of Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li & Valerie C. L. Lin
Additional file 4. 1341 Differentially expressed genes between the WT and AF1_FFF uterus on GD4.5.

The complete chloroplast genome of Primula odontocalyx, a heterostylous species

Yunqi Liu, Li Zhang, Shubao Wang, Rui Li & Yuan Huang
Primula odontocalyx (Franch.) Pax (1905) is a perennial herb of the genus Primula in Primulaceae with heterostyly and ornamental value. Here, the chloroplast genome of P. odontocalyx was sequenced, assembled, and annotated. The complete chloroplast genome was a closed-circular molecule of 151,738 bp in length, containing a large single-copy region (LSC) of 83,817 bp, a small single-copy region (SSC) of 17,529 bp, and two inverted repeat (IR) regions of 25,196 bp. A total of 115...

RDD2022 - The multi-national Road Damage Dataset released through CRDDC'2022

D Arya, Hiroya Maeda, Yoshihide Sekimoto, Hiroshi Omata, Sanjay Kumar Ghosh, Durga Toshniwal, Madhavendra Sharma, Van Vung Pham, Jingtao Zhong, Muneer Al-Hammadi, Mamoona Birkhez Shami, Du Nguyen, Hanglin Cheng, Jing Zhang, Alex Klein-Paste, Helge Mork, Frank Lindseth, Toshikazu Seto, Alexander Mraz & Takehiro Kashiyama
Description The Road Damage Dataset, RDD2022, is released as a part of the Crowdsensing-based Road Damage Detection Challenge (CRDDC'2022), an IEEE BigData Cup. It comprises 47,420 road images from six countries, Japan, India, the Czech Republic, Norway, the United States, and China. The images have been annotated with more than 55,000 instances of road damage. Four types of road damage, namely longitudinal cracks, transverse cracks, alligator cracks, and potholes, are captured in the dataset....

VIBRATION CHARACTERISTICS, CHEMICAL BONDS AND WEAK INTERACTIONS OF 4- AND 5-HYDROXYSALICYLIC ACID INVESTIGATED BY TERAHERTZ SPECTROSCOPY AND DENSITY FUNCTIONAL THEORY

Yuan Tang, Zhi Li, Yan Guo, Xianhua Yin, Shan Tu & Dapeng Zhang
The terahertz (THz) absorption spectra of 4- and 5-hydroxysalicylic acid were measured by terahertz time-domain spectroscopy (THz-TDS) in the range of 0.4-2.8 THz. The unit cells of both were calculated by density functional theory (DFT), and the theoretical simulation and experimental data were basically in agreement. To further interpret the origin of the characteristic absorption peaks, vibration characteristics and interactions of the unit cell model were analyzed by using potential energy distribution (PED) and interaction...

Additional file 1 of Integrative analyses of maternal plasma cell-free DNA nucleosome footprint differences reveal chromosomal aneuploidy fetuses gene expression profile

Min Zhang, Kun Li, Shoufang Qu, Zhiwei Guo, Yuanli Wang, Xu Yang, Junhua Zhou, Guojun Ouyang, Rongtao Weng, Fenxia Li, Yingsong Wu & Xuexi Yang
Additional file 1: Table S1. Differential promoter coverage genes and GO, KEGG enrichment analysis results of differential genes for all pregnant women with trisomy.

Additional file 2 of Integrative analyses of maternal plasma cell-free DNA nucleosome footprint differences reveal chromosomal aneuploidy fetuses gene expression profile

Min Zhang, Kun Li, Shoufang Qu, Zhiwei Guo, Yuanli Wang, Xu Yang, Junhua Zhou, Guojun Ouyang, Rongtao Weng, Fenxia Li, Yingsong Wu & Xuexi Yang
Additional file 2: Table S2. Differential promoter coverage genes and GO, KEGG enrichment analysis results of differential genes for pregnant women with trisomy 21.

Registration Year

  • 2022
    151

Resource Types

  • Dataset
    151

Affiliations

  • Lanzhou Veterinary Research Institute
    151
  • Jilin University
    118
  • Chinese Academy of Sciences
    113
  • Tongji University
    103
  • Capital Medical University
    102
  • University of Chinese Academy of Sciences
    96
  • Sun Yat-sen University
    95
  • Lanzhou University
    95
  • Zhejiang University
    93
  • Fujian Medical University
    85