6 Works

Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro

Qiao Wu, Pengfei Yu, Yanzhen Bi, Zhijie Li, Wei Guo, Yu Chen & Zhongping Duan
Naringin (Nar) has been reported to exert potential hepatoprotective effects against acetaminophen (APAP)-induced injury. Mitochondrial dysfunction plays an important role in APAP-induced liver injury. However, the protective mechanism of Nar against mitochondrial damage has not been elucidated. Therefore, the aim of this study was to investigate the hepatoprotective effects of Nar against APAP and the possible mechanisms of actions. Primary rat hepatocytes and HepG2 cells were utilized to establish an in vitro model of APAP-induced...

Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro

Qiao Wu, Pengfei Yu, Yanzhen Bi, Zhijie Li, Wei Guo, Yu Chen & Zhongping Duan
Naringin (Nar) has been reported to exert potential hepatoprotective effects against acetaminophen (APAP)-induced injury. Mitochondrial dysfunction plays an important role in APAP-induced liver injury. However, the protective mechanism of Nar against mitochondrial damage has not been elucidated. Therefore, the aim of this study was to investigate the hepatoprotective effects of Nar against APAP and the possible mechanisms of actions. Primary rat hepatocytes and HepG2 cells were utilized to establish an in vitro model of APAP-induced...

Additional file 9 of Variety-Specific Transcriptional and Alternative Splicing Regulations Modulate Salt Tolerance in Rice from Early Stage of Stress

Guihua Jian, Yujian Mo, Yan Hu, Yongxiang Huang, Lei Ren, Yueqin Zhang, Hanqiao Hu, Shuangxi Zhou, Gang Liu, Jianfu Guo & Yu Ling
Additional file 9: Supplementary tables for more detailed information for RNA-Seq data analyses.

IL-27 overexpression alleviates inflammatory response in allergic asthma by inhibiting Th9 differentiation and regulating Th1/Th2 balance

Peng Xiong, Tonglin Liu, Hao Huang, Yi Yuan, Wendi Zhang, Lina Fu & Yu Chen
To investigate the effect of IL-27 on Th9 differentiation and Th1/Th2 balance. C57BL/6 (B6) mice were treated with ovalbumin to establish an allergic asthma (AA) model and subjected to IL-27 overexpression (OV) and empty vector (EV). Hematoxylin-eosin (HE) staining was performed to observe lung tissue inflammation. Flow cytometry was carried out to evaluate the percentage of Th9, Th1, and Th2 cells. The expression of IL-27, IL-27R, IL-9, T-bet, IFN-γ, and IgE was evaluated by quantitative...

IL-27 overexpression alleviates inflammatory response in allergic asthma by inhibiting Th9 differentiation and regulating Th1/Th2 balance

Peng Xiong, Tonglin Liu, Hao Huang, Yi Yuan, Wendi Zhang, Lina Fu & Yu Chen
To investigate the effect of IL-27 on Th9 differentiation and Th1/Th2 balance. C57BL/6 (B6) mice were treated with ovalbumin to establish an allergic asthma (AA) model and subjected to IL-27 overexpression (OV) and empty vector (EV). Hematoxylin-eosin (HE) staining was performed to observe lung tissue inflammation. Flow cytometry was carried out to evaluate the percentage of Th9, Th1, and Th2 cells. The expression of IL-27, IL-27R, IL-9, T-bet, IFN-γ, and IgE was evaluated by quantitative...

Additional file 9 of Variety-Specific Transcriptional and Alternative Splicing Regulations Modulate Salt Tolerance in Rice from Early Stage of Stress

Guihua Jian, Yujian Mo, Yan Hu, Yongxiang Huang, Lei Ren, Yueqin Zhang, Hanqiao Hu, Shuangxi Zhou, Gang Liu, Jianfu Guo & Yu Ling
Additional file 9: Supplementary tables for more detailed information for RNA-Seq data analyses.

Registration Year

  • 2022
    6

Resource Types

  • Dataset
    6

Affiliations

  • Jiangsu Second Normal University
    6
  • Huazhong University of Science and Technology
    6
  • Fudan University
    6
  • Capital Medical University
    6
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    6
  • Beijing Tian Tan Hospital
    4
  • Sun Yat-sen University
    4
  • Shanghai University
    4
  • University of Alabama at Birmingham
    4
  • National Yang Ming Chiao Tung University
    4