Data from: Psychostimulant-induced testicular toxicity in mice: evidence of cocaine and caffeine effects on the local dopaminergic system

Candela R. González, Betina González, Maria E. Matzkin, Javier A. Muñiz, Jean Lud Cadet, Edgar Garcia-Rill, Francisco J. Urbano, Alfredo D. Vitullo & Veronica Bisagno
Several organ systems can be affected by psychostimulant toxicity. However, there is not sufficient evidence about the impact of psychostimulant intake on testicular physiology and catecholaminergic systems. The aim of the present study was to further explore potential toxic consequences of chronic exposure to cocaine, caffeine, and their combination on testicular physiology. Mice were injected with a 13-day chronic binge regimen of caffeine (3x5mg/kg), cocaine (3×10mg/kg), or combined administration. Mice treated with cocaine alone or...

Registration Year

  • 2016
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Affiliations

  • University of Buenos Aires
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  • National Institute on Drug Abuse
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  • University of Arkansas for Medical Sciences
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  • Universidad Maimónides
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  • Experimental Medicine and Biology Institute
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