2 Works

Data from: Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia

Werner C. Albrich, Shabir A. Madhi, Peter V. Adrian, Nadia Van Niekerk, Jean-Noel Telles, Naseem Ebrahim, Melina Messaoudi, Glaucia Paranhos-BaccalĂ , Sven Giersdorf, Guy Vernet, Beat Mueller & Keith P. Klugman
Objective: A high genomic load of Pneumococcus from blood or cerebrospinal fluid has been associated with increased mortality. We aimed to analyse whether nasopharyngeal colonisation density in HIV-infected patients with community-acquired pneumonia (CAP) is associated with markers of disease severity or poor outcome. Methods: Quantitative lytA real-time PCR was performed on nasopharyngeal swabs in HIV-infected South African adults hospitalised for acute CAP at Chris Hani Baragwanath Hospital, Soweto, South Africa. Pneumonia aetiology was considered pneumococcal...

Data from: Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials

Leonard H Van Den Berg, Eric Sorenson, Gary Gronseth, Eric A. Macklin, Jinsy Andrews, Robert H. Baloh, Michael Benatar, James D. Berry, Adriano Chio, Philippe Corcia, Angela Genge, Amelie K. Gubitz, Catherine Lomen-Hoerth, Christopher J. McDermott, Erik P. Pioro, Jeffrey Rosenfeld, Vincenzo Silani, Martin R. Turner, Markus Weber, Benjamin Rix Brooks, Robert G. Miller & Hiroshi Mitsumoto
Objective: To revise the 1999 Airlie House consensus guidelines for the design and implementation of preclinical therapeutic studies and clinical trials in amyotrophic lateral sclerosis (ALS). Methods: A consensus committee comprising 140 key members of the international ALS community (ALS researchers, clinicians, patient representatives, research funding representatives, industry and regulatory agencies) addressed nine areas of need within ALS research: 1. Pre-clinical studies; 2. Biological and phenotypic heterogeneity; 3. Outcome measures; 4. Disease-modifying and symptomatic interventions;...

Registration Year

  • 2019
    1
  • 2014
    1

Resource Types

  • Dataset
    2

Affiliations

  • Kantonsspital St. Gallen
    2
  • Massachusetts General Hospital
    1
  • Stanford University
    1
  • Columbia University
    1
  • University of Milan
    1
  • National Institutes of Health
    1
  • Fondation MĂ©rieux
    1
  • McGill University
    1
  • University of Miami
    1
  • Cedars-Sinai Medical Center
    1