4 Works

Data from: Contrasting effects of phylogenetic relatedness on plant invader success in experimental grassland communities

Shao-Peng Li, Tao Guo, Marc W. Cadotte, Yong-Jian Chen, Jia-Liang Kuang, Zheng-Shuang Hua, Yi Zeng, Ying Song, Zheng Liu, Wen-Sheng Shu & Jin-Tian Li
1. Identifying the factors determining the success of invasive species is critical for management of biological invasions. Darwin's naturalization conundrum states that exotic species closely related to natives should be successful because of a shared affinity for local environmental conditions, but at the same time close relatives often compete more intensively, limiting ‘niche’ opportunities for the invaders. Previous studies have generally considered these two ‘opposing’ hypotheses as mutually exclusive, yet evidence for both of them...

Data from: Season-specific and guild-specific effects of anthropogenic landscape modification on metacommunity structure of tropical bats

Laura M. Cisneros, Matthew E. Fagan & Michael R. Willig
1. Fragmentation per se due to human land conversion is a landscape-scale phenomenon. Accordingly, assessment of distributional patterns across a suite of potentially connected communities (i.e. metacommunity structure) is an appropriate approach for understanding the effects of landscape modification, and complements the plethora of fragmentation studies that have focused on local community structure. To date, metacommunity structure within human-modified landscapes has been assessed with regard to nestedness along species richness gradients. This is problematic because...

Data from: A comparison of single nucleotide polymorphism and microsatellite markers for analysis of parentage and kinship in a cooperatively breeding bird

Lucia R. Weinman, Joseph W. Solomon & Dustin R. Rubenstein
The development of genetic markers has revolutionized molecular studies within and among populations. Although poly-allelic microsatellites are the most commonly used genetic marker for within-population studies of free-living animals, biallelic single nucleotide polymorphisms, or SNPs, have also emerged as a viable option for use in nonmodel systems. We describe a robust method of SNP discovery from the transcriptome of a nonmodel organism that resulted in more than 99% of the markers working successfully during genotyping....

Data from: Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Scott J. Dixon, Darpan N. Patel, Matthew Welsch, Rachid Skouta, Eric D. Lee, Ajit G. Thomas, Caroline E. Gleason, Nicholas Tatonetti, Barbara S. Slusher, Brent R. Stockwell, Miki Hayano & Nicholas P Tatonetti
Exchange of extracellular cystine for intracellular glutamate by the antiporter system xc− is implicated in numerous pathologies. Pharmacological agents that inhibit system xc− activity with high potency have long been sought, but have remained elusive. In this study, we report that the small molecule erastin is a potent, selective inhibitor of system xc−. RNA sequencing revealed that inhibition of cystine–glutamate exchange leads to activation of an ER stress response and upregulation of CHAC1, providing a...

Registration Year

  • 2014
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Resource Types

  • Dataset
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Affiliations

  • Columbia University
    4
  • Sun Yat-sen University
    1
  • University of Connecticut
    1
  • Johns Hopkins Medicine
    1
  • University of Toronto
    1