13 Works

Post-processed data for: Diverse operant control of different motor cortex populations during learning

Nuria Vendrell-Llopis, Ching Fang, Albert Qü, Rui Costa & Jose Carmena
We tested two population of cortical neurons, intra-telencephalic (IT) and extra-telencephalic or pyramidal tract (PT) neurons, as direct neurons for neuroprosthetic control. We labelled different cell-classes in two groups of mice and trained them to modulate the activity of either IT or PT neurons to control a Ca-imaging based brain-machine interface (CaBMI). In addition, we used machine learning and game theory approaches to reverse-engineer the learning outcome and dissect the causal contributions of cell-class, neuronal...

Flexible use of memory by food-caching birds

Marissa Applegate & Dmitriy Aronov
Animals use memory-guided and memory-independent strategies to make navigational decisions. Disentangling the contribution of these strategies to navigation is critical for understanding how memory influences behavioral output. To address this issue, we studied spatial behaviors of the chickadee, a food-caching bird. Chickadees hide food in concealed, scattered locations and retrieve their caches later in time. We designed an apparatus that allows birds to cache and retrieve food at many sites while navigating in a laboratory...

Data from: Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence

Shabnam Mohammadi, Santiago Herrera-Álvarez, Lu Yang, María Del Pilar Rodríguez-Ordoñez, Karen Zhang, Jay F. Storz, Susanne Dobler, Andrew J. Crawford & Peter Andolfatto
A growing body of theoretical and experimental evidence suggests that intramolecular epistasis is a major determinant of rates and patterns of protein evolution and imposes a substantial constraint on the evolution of novel protein functions. Here, we examine the role of intramolecular epistasis in the recurrent evolution of resistance to cardiotonic steroids (CTS) across tetrapods, which occurs via specific amino acid substitutions to the α-subunit family of Na,K-ATPases (ATP1A). After identifying a series of recurrent...

A deglacial hazard cascade exemplified by the landslide, tsunami and outburst flood at Elliot Creek, Southern Coast Mountains, British Columbia, Canada

Marten Geertsema, Brian Menounos, Gemma Bullard, Jonathan Carrivick, John Clague, Chunli Dai, Davide Donati, Goran Ekstrom, Jennifer Jackson, Patrick Lynett, Manuele Pichierri, Andy Pon, Dan Shugar, Doug Stead, Justin Del Bel Belluz, Pierre Friele, Ian Giesbrecht, Derek Heathfield, Tom Millard, Sasha Nasonova, Andrew Schaeffer, Brent Ward, Darren Blaney, Erik Blaney, Camille Brillon … & Meghan Sharp
We describe and model the evolution of a recent landslide and outburst flood in the southern Coast Mountains, British Columbia, Canada. About 18 Mm3 of rock descended 1000 m from a steep valley wall and traveled across the toe of a glacier before entering a 0.6 km2 glacier lake and producing a >100-m high wave. Water overtopped the lake outlet and scoured a 10-km long channel before depositing debris on a 2 km2 fan below...

Trophic complexity alters the diversity–multifunctionality relationship in experimental grassland mesocosms

Krishna Anujan, Shahid Naeem, Sebastian A. Heilpern, Case M. Prager & Brian C. Weeks
Plant diversity has a positive influence on the number of ecosystem functions maintained simultaneously by a community, or multifunctionality. While the presence of multiple trophic levels, or trophic complexity, affects individual functions, the effect of trophic complexity on the diversity-multifunctionality relationship is less well known. To address this issue, we tested whether the independent or simultaneous manipulation of both plant diversity and trophic complexity impacted multifunctionality using a mecocosm experiment from Cedar Creek, Minnesota, USA....


Helen Janiszewski, Zachary Eilon, Joshua Russell, Brennan Brunsvik, James Gaherty, Stephen Mosher, William Hawley & Sloan Coats
We present a new compilation and analysis of broadband ocean bottom seismometer noise properties from 15 years of seismic deployments. We compile a comprehensive dataset of representative four-component (seismometer and pressure gauge) noise spectra and cross-spectral properties (coherence, phase, and admittance) for 551 unique stations spanning 18 US-led experiments. This is matched with a comprehensive compilation of metadata parameters related to instrumentation and environmental properties for each station. We systematically investigate the similarity of noise...

Age-specific activation patterns and inter-subject similarity during verbal working-memory maintenance and Cognitive Reserve

Christian Habeck, Yunglin Gazes & Yaakov Stern
Cognitive Reserve, according to a recent consensus definition of the NIH-funded Reserve and Resilience collaboratory (https://reserveandresilience.com/), is constituted by any mechanism contributing to cognitive performance beyond, or interacting with, brain structure in the widest sense. To identity multivariate activation patterns fulfilling this postulate, we investigated a verbal Sternberg fMRI task and imaged 181 people with age coverage in the ranges 20-30 (44 participants) and 55-70 (137 participants). Beyond task performance, participants were characterized in terms...

Data from: Juvenile experience with male cues triggers cryptic choice mechanisms in adult female redback spiders

Maydianne C.B. Andrade, Aiswarya Baskaran, Maria Daniela Biaggio & Maria Modanu
Female choice may be linked to population density if expected encounter rates with potential mates affects choosiness (energy and risk engaged to express mate preferences). Choosiness should covary with male availability, which could be assessed using social cues available during development. We tested whether exposure of juvenile females to cues of male density affected mechanisms of choosiness of adult Latrodectus hasselti spiders in two experiments simulating natural contexts. Juvenile females were exposed to (1) volatile...

Supporting data from: Characterizing changes in eastern U.S. pollution events in a warming world

George Milly
Risk assessments of air pollution impacts on human health and ecosystems would ideally consider a broad set of climate and emission scenarios, as well as natural internal climate variability. We analyze initial condition chemistry-climate ensembles to gauge the significance of greenhouse-gas-induced air pollution changes relative to internal climate variability, and consider response differences in two models. To quantify the effects of climate change on the frequency and duration of summertime regional-scale pollution episodes over the...

Alignments of chloroplast noncoding regions for context-dependency analysis

Brian Morton
Substitutions between closely related noncoding chloroplast DNA sequences are studied with respect to the composition of the three bases on each side of the substitution, that is the hexanucleotide context. There is about 100-fold variation in rate, amongst the contexts, particularly on substitutions of A and T. Rate heterogeneity of transitions differs from that of transversions, resulting in a more than 200-fold variation in the transitions:transversion bias. The data are consistent with a CpG effect,...

Intrinsic excitability mechanisms of neuronal ensemble formation

Tzitzitlini Alejandre-García, Samuel Kim, Jesús Pérez-Ortega & Rafael Yuste
Neuronal ensembles are coactive groups of cortical neurons, found in spontaneous and evoked activity, that can mediate perception and behavior. To understand the mechanisms that lead to the formation of ensembles, we co-activated optogenetically and electrically layer 2/3 pyramidal neurons in brain slices from mouse visual cortex, in animals from both sexes, replicating in vitro an optogenetic protocol to generate ensembles in vivo. Using whole-cell and perforated patch-clamp pair recordings we find that, after optogenetic...

Demographic rates and stature of tree species in 13 sub-tropical forests: annual growth, annual survival, annual recruitment >( 1 cm dbh), stature (max dbh)

Stephan Kambach, Richard Condit, Salomón Aguilar, Helge Bruelheide, Sarayudh Bunyavejchewin, Chia-Hao Chang-Yang, Yu-Yun Chen, George Chuyong, Stuart J. Davies, Sisira Ediriweera, Corneille E. N. Ewango, Edwino S. Fernando, Nimal Gunatilleke, Savitri Gunatilleke, Stephen P Hubbell, Akira Itoh, David Kenfack, Somboon Kiratiprayoon, Yi-Ching Lin, Jean-Remy Makana, Mohizah Bt. Mohamad, Nantachai Pongpattananurak, Rolando Pérez, Lillian Jennifer V. Rodriguez, I-Fang Sun … & Nadja Rüger
Organisms of all species must balance their allocation to growth, survival and recruitment. Among tree species, evolution has resulted in different life-history strategies for partitioning resources to these key demographic processes. Life-history strategies in tropical forests have often been shown to align along a trade-off between fast growth and high survival, i.e. the well-known fast-slow continuum. In addition, an orthogonal trade-off has been proposed between tall stature – resulting from fast growth and high survival...

Longitudinal trends of EHR concepts in pediatric patients

Nicholas Giangreco
The longitudinal nature of the data motivated temporal trend identification in the pediatric EHR datatypes. Over the past three decades (1980-2018), we identified and quantified the temporal trend of 16,460 EHR concepts across measurement, visit, diagnosis, drug, and procedure datatypes.

Registration Year

  • 2022

Resource Types

  • Dataset


  • Columbia University
  • Thammasat University
  • Universität Hamburg
  • Princeton University
  • Field Museum of Natural History
  • National Sun Yat-sen University
  • National Dong Hwa University
  • UK Centre for Ecology & Hydrology
  • 3v Geomatics (Canada)
  • Oregon State University