Additional file 5 of Lrpap1 deficiency leads to myopia through TGF-β-induced apoptosis in zebrafishShanshan Liu, Ting Chen, Binghao Chen, Yijun Liu, Xiaohe Lu & Jiali Li
Additional file 4. Supplementary Table S3. Information of 165 apoptosis pathway related genes in GSEA analysis.
Additional file 7 of Lrpap1 deficiency leads to myopia through TGF-β-induced apoptosis in zebrafishShanshan Liu, Ting Chen, Binghao Chen, Yijun Liu, Xiaohe Lu & Jiali Li
Additional file 6. Supplementary Table S5. Gene information of KEGG analysis.
Additional file 21 of Transcriptomic analysis of paternal behaviors in prairie volesFlorian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 21. Number of immediate early genes (IEG) in the genes differentially expressed in the medial preoptic area (MPOA), nucleus accumbens (NAc), and lateral septum (LS).
Additional file 4 of Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltrationWei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Additional file 4: Table S3. The results of univariate Cox proportional hazards regression analyses between clinical features and risk score in the training, testing, and entire sets.
Additional file 5 of Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltrationWei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Hong-He Luo, Yan-Fen Feng & Yi-Yan Lei
Additional file 5: Table S4. The results of univariate Cox proportional hazards regression analyses between clinical features and risk score in the training, testing, and entire sets.
Additional file 4 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf developmentXueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 4: Table S2. List of 2,443 leaf-specific genes.
Additional file 3 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf developmentXueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 3: Table S1 Analysis of variance for LL, LW and LA in an F1 population using mixed model for two years in two locations (CP and LF)
SNP of Opisthopappus speciesHao Zhang
The VCF file for article DOI: 10.22541 / au/v1 part of 166870495.51723721.
Additional file 23 of Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinomaYexin Tong, Mingjun Sun, Lingli Chen, Yunzhi Wang, Yan Li, Lingling Li, Xuan Zhang, Yumeng Cai, Jingbo Qie, Yanrui Pang, Ziyan Xu, Jiangyan Zhao, Xiaolei Zhang, Yang Liu, Sha Tian, Zhaoyu Qin, Jinwen Feng, Fan Zhang, Jiajun Zhu, Yifan Xu, Wenhui Lou, Yuan Ji, Jianyuan Zhao, Fuchu He, Yingyong Hou … & Chen Ding
Additional file 23: Table S1. Clinicopathologic Information and Multi-omics Data in PDAC Cohort. Table S1A Multi-omics information of PDAC cohort. Table S1B Clinicopathologic information of the 229 PDAC.
CIED-Emission factors, 2015-2018Ling Tang, Min Jia, Junai Yang, Ling Li, Xin Bo & Zhifu Mi
The Chinese Industrial Emissions Database (CIED) provides inventory of particulate matter (PM), SO2 and NOX from Chinese industries from 2015 to 2018, based on direct measurements from China’s continuous emission monitoring systems (CEMS) network. This document provides emissions factors for China’s different industrial emission sources.
CIED-Absolute emissions, 2015-2018Ling Tang, Min Jia, Junai Yang, Ling Li, Xin Bo & Zhifu Mi
The Chinese Industrial Emissions Database (CIED) provides inventory of particulate matter (PM), SO2 and NOX from Chinese industries from 2015 to 2018, based on direct measurements from China’s continuous emission monitoring systems (CEMS) network. This document provides absolute emissions for China’s different industrial emission sources.
High-throughput sequencing to evaluate the effects of methamphetamine on the succession of the bacterial community to estimate the postmortem intervalShujuan Wang, Wei Chen, Yanjie Shang, Lipin Ren, Xiangyan Zhang, Yadong Guo & Changquan Zhang
In forensic medical examinations, estimating the postmortem interval (PMI) is an important factor. Methamphetamine (MA) is a synthetic stimulant that is commonly abused, and estimation of the PMI after MA abuse has become one of the main tasks in forensic investigation. Microorganisms play a vital role in carrion decomposition. Analysing the bacterial succession patterns can be used as a forensic tool to estimate the PMI. The present study aimed to analyse bacterial succession changes during...
A nucleic acid detection assay combining reverse transcription recombinase-aided amplification with a lateral flow dipstick for the rapid visual detection of porcine deltacoronavirusJianyu Zeng, Wenlong Wang, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Yanhong Chen, Yongning Zhang & Hanchun Yang
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogen causing severe diarrhoea, dehydration, and death in nursing piglets and enormous economic losses for the global swine industry. Furthermore, it can infect multiple animal species including humans. Therefore, a rapid, definitive diagnostic assay is required for the effective control of this zoonotic pathogen. To identify PDCoV, we developed a nucleic acid detection assay combining reverse transcription recombinase-aided amplification (RT-RAA) with a lateral flow dipstick (LFD) targeting the highly...
BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cellsTingting Gao, Meng Lin, Binbin Shao, Qiao Zhou, Yufeng Wang, Xia Chen, Dan Zhao, Xiuliang Dai, Cong Shen, Hongbo Cheng, Shenmin Yang, Hong Li, Bo Zheng, Xingming Zhong, Jun Yu, Li Chen & Xiaoyan Huang
In males, aging is accompanied by decline in serum testosterone levels due to impairment of testicular Leydig cells. The polycomb protein BMI1 has recently been identified as an anti-aging factor. In our previous study, BMI1 null mice showed decreased serum testosterone and Leydig cell population, excessive oxidative stress and p16/p19 signaling activation. However, a cause-and-effect relationship between phenotypes and pathways was not investigated. Here, we used the rescue approach to study the role of oxidative...
Upregulated circRNA hsa_circ_0071036 promotes tumourigenesis of pancreatic cancer by sponging miR-489 and predicts unfavorable characteristics and prognosisXu Han, Yuan Fang, Pingping Chen, Yaolin Xu, Wentao Zhou, Yefei Rong, Jian-Ang Li, Wei Chen & Wenhui Lou
Circular RNAs (circRNAs), the new stars of endogenous non-coding RNAs, are dysregulated in various tumors including pancreatic cancer. Here, we aimed to investigate the biological functions of hsa_circ_0071036 in the tumourigenesis and progression of pancreatic ductal adenocarcinoma (PDAC) and its clinical implications. The differential expression profile of circRNAs in 4 pairs of PDAC tissues was analyzed by microarray assay. Quantitative real-time PCR and fluorescence in situ hybridization (FISH) were utilized to determine the expression patterns...
NSUN2-mediated M5c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infectionsHongyun Wang, Jiangpeng Feng, Cong Zeng, Jiejie Liu, Zhiying Fu, Dehe Wang, Yafen Wang, Lu Zhang, Jiali Li, Ao Jiang, Miao He, Yuanyuan Cao, Kun Yan, Hao Tang, Deyin Guo, Ke Xu, Xiang Zhou, Li Zhou, Ke Lan, Yu Zhou & Yu Chen
5-Methylcytosine (m5C) is a widespread post-transcriptional RNA modification and is reported to be involved in manifold cellular responses and biological processes through regulating RNA metabolism. However, its regulatory role in antiviral innate immunity has not yet been elucidated. Here, we report that NSUN2, a typical m5C methyltransferase, negatively regulates type I interferon responses during various viral infections, including SARS-CoV-2. NSUN2 specifically mediates m5C methylation of IRF3 mRNA and accelerates its degradation, resulting in low levels...
The Relationship Between Food Insecurity and Food Assistance Program Participation in Families of Preschool Children in the Rio Grande ValleyLisa Michelle Belzer Salinas, Michael Machiorlatti, Zasha Romero, Lin Wang, Elizabeth Alanis & Roberto Treviño-Peña
The South Texas Early Prevention Study-PreK, a cluster randomized trial, explored the Bienestar Coordinated School Health Program’s influence on health variables in South Texas children. Factors associated with food insecurity (FI) were analyzed. Income-to-poverty ratio, income, and food assistance (FA) program participation were all associated with FI. Forty percent of families (257/643) reporting FI did not utilize FA. Of those families with FI, but who reported no FA participation, 31.8% were FA eligible. Families experiencing...
Functional Outlier Detection for Density-Valued Data with Application to Robustify Distribution-to-Distribution RegressionXinyi Lei, Zhicheng Chen & Hui Li
Distributional data analysis, concerned with the statistical analysis of data objects consisting of random probability distributions in the framework of functional data analysis (FDA), has received considerable interest in recent years and is increasingly applied in various fields including engineering. Outlier detection and robustness are of great practical interest; however, these aspects remain unexplored for distributional data. To this end, this study focuses on density-valued outlier detection and its application in robust distributional regression. Specifically,...
Table S2: Zircon U–Pb geochronology and Hf isotopic compositions of igneous rocks from Sumatra: implications for the Cenozoic magmatic evolution of the western Sunda ArcYu-Ming Lai, Ping-Ping Liu, Sun-Lin Chung, Azman A. Ghani, Hao-Yang Lee, Long Xiang Quek, Shan Li, Muhammad Hatta Roselee, Sayed Murtadha, Lediyantje Lintjewas & Yoshiyuki Iizuka
Zircon U–Pb ages used in this study.
A Two-Sample Conditional Distribution Test Using Conformal Prediction and Weighted Rank SumXiaoyu Hu & Jing Lei
We consider the problem of testing the equality of conditional distributions of a response variable given a vector of covariates between two populations. Such a hypothesis testing problem can be motivated from various machine learning and statistical inference scenarios, including transfer learning and causal predictive inference. We develop a nonparametric test procedure inspired from the conformal prediction framework. The construction of our test statistic combines recent developments in conformal prediction with a novel choice of...
Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activationTao Wu, Shengmin Xu, Biao Chen, Lingzhi Bao, Jie Ma, Wei Han, An Xu, Kwan Ngok Yu, Lijun Wu & Shaopeng Chen
Ambient PM2.5 is one of the environmental risk factors and was correlated with senescence-related diseases based on the epidemiologic investigation. However, little is known about senescence induced by PM2.5 as well as the underlying mechanisms. In this study, we demonstrated that PM2.5 exposure aggravated cellular senescence in vivo and in vitro, and disrupted micronuclei (MN) played a vital role in this process. Our results suggested that the nuclear envelope (NE) of PM2.5-induced MN was ruptured....
Therapeutic effects of Panax notoginseng saponins in rheumatoid arthritis: network pharmacology and experimental validationXinnan Ma, Xin Zhang, Yuanhang Kong, Bo Su, Leilei Wu, Daqian Liu & Xintao Wang
Panax notoginseng saponins (PNS) have been reported to have good anti-inflammatory effects. However, the anti-inflammatory effect mechanism in rheumatoid arthritis (RA) remains unknown. The focus of this research was to investigate the molecular mechanism of PNS in the treatment of RA. The primary active components of PNS were tested utilizing the Traditional Chinese Medicine Systems Pharmacology Database (TCMSP) and Analysis Platform based on oral bioavailability and drug-likeness. The target databases for knee osteoarthritis were created...
The effect of insulin and kruppel like factor 10 on osteoblasts in the dental implant osseointegration in diabetes mellitus patientsChen Sheng, Yalin Guo, Wenjie Hou, Haobin Chen, Hongchen Liu & Lin Wang
Diabetes mellitus, metabolic disease, is characterized by chronic hyperglycemia. Patients with diabetes mellitus are susceptible to infection and therefore have a higher prevalence and progression rate of periodontal disease. We aimed to study the effect of insulin and kruppel like factor 10 (KLF10) on osteoblasts proliferation and differentiation, and expression of bone metabolism-related molecules and related signaling pathway molecules of AKT serine/threonine kinase 1 (AKT) and nuclear factor kappa B subunit 1 (NF-κB) through in...
Additional file 11 of FMO3 deficiency of duck leads to decreased lipid deposition and increased antibacterial activityXingzheng Li, Jianlou Song, Xuefeng Shi, Mingyi Huang, Lei Liu, Guoqiang Yi, Ning Yang, Guiyun Xu & Jiangxia Zheng
Additional file 11: Table S4. Taxa associated with TMA metabolism using the Mann-Whitney U-test.
sj-xlsx-1-pdp-10.1177_10935266221132602 – Supplemental material for Calretinin Staining in Anorectal Line Biopsies Accurately Distinguished Hirschsprung Disease in a Retrospective StudySuzanna J. Logan, Hong Yin, Beverly Rogers, Nicoleta Arva, Miriam R. Conces, Sandy Cope-Yokoyama, Louis P. Dehner, Carlos Galliani, Shipra Garg, Mai He, Aliya N. Husain, Matthew Keisling, Chandra Krishnan, Elena Puscasiu, Christopher Rossi, Faiza Siddiqui, Lisa Sutton, Jefferson Terry, Ameet I. Thaker, Yuan Huang, Jie Zhang, Courtney McCracken & Heather Rytting
Supplemental material, sj-xlsx-1-pdp-10.1177_10935266221132602 for Calretinin Staining in Anorectal Line Biopsies Accurately Distinguished Hirschsprung Disease in a Retrospective Study by Suzanna J. Logan, Hong Yin, Beverly Rogers, Nicoleta Arva, Miriam R. Conces, Sandy Cope-Yokoyama, Louis P. Dehner, Carlos Galliani, Shipra Garg, Mai He, Aliya N. Husain, Matthew Keisling, Chandra Krishnan, Elena Puscasiu, Christopher Rossi, Faiza Siddiqui, Lisa Sutton, Jefferson Terry, Ameet I. Thaker, Yuan Huang, Jie Zhang, Courtney McCracken and Heather Rytting in Pediatric and Developmental...
Chinese Academy of Medical Sciences & Peking Union Medical College781
Shanghai Jiao Tong University702
Chinese Academy of Sciences575
Sun Yat-sen University566
University of Chinese Academy of Sciences534
Huazhong University of Science and Technology531