755 Works
Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains
Jianping Wang, Pujun Liang, Hui Sun, Zongfu Wu, Marcelo Gottschalk, Kexin Qi & Han Zheng
Streptococcus suis epidemic strains were responsible for two outbreaks in China and possessed increased pathogenicity which was featured prominently by inducing an excessive inflammatory response at the early phase of infection. To discover the critical genes responsible for the pathogenicity increase of S. suis epidemic strains, the genome-wide transcriptional profiles of epidemic strain SC84 were investigated at the early phase of interaction with BV2 cells. The overall low expression levels of 89K pathogenicity island (PAI)...
Multimolecular characteristics of cell-death related hub genes in human cancers: a comprehensive pan-cancer analysis
Dingtao Hu, Tingyu Zhang, Ziye Yan, Linlin Wang, Yuhua Wang, Nana Meng, Bizhi Tu, Ying Teng, Zhen Li, Xiaoqi Lou, Yu Lei, Xiaoshuang Ren, Yanfeng Zou & Fang Wang
Failure of the normal process of cell death pathways contributes to the defection of immune systems and the occurrence of cancers. The key genes, the multimolecular mechanisms, and the immune functions of these genes in pan-cancers remain unclear. Using online databases of The Cancer Genome Atlas, GEPIA2, TISIDB, HPA, Kaplan-Meier Plotter, PrognoScan, cBioPortal, GSCALite, TIMER, and Sangerbox, we identified the key genes from the six primary cell death-related pathways and performed a comprehensive analysis to...
The complete chloroplast genome of Primula odontocalyx, a heterostylous species
Yunqi Liu, Li Zhang, Shubao Wang, Rui Li & Yuan Huang
Primula odontocalyx (Franch.) Pax (1905) is a perennial herb of the genus Primula in Primulaceae with heterostyly and ornamental value. Here, the chloroplast genome of P. odontocalyx was sequenced, assembled, and annotated. The complete chloroplast genome was a closed-circular molecule of 151,738 bp in length, containing a large single-copy region (LSC) of 83,817 bp, a small single-copy region (SSC) of 17,529 bp, and two inverted repeat (IR) regions of 25,196 bp. A total of 115...
FLEXIBILITY TRAINING IMPROVES ELEGANCE IN ICE BALLET
Yu Zhou
ABSTRACT Introduction Ice ballet is performed through various movements with high artistic attributes such as skating, foot movement, rotation, and jumping on ice. The development of ice ballet flexibility can make the movements more graceful and coordinated and improve muscle strength. The athlete’s flexibility can prevent accidents and reduce injuries. Objective This study aimed to analyze the effect of body flexibility on improving movement skills in ice ballet. Methods This paper selects ten ice ballet...
Additional file 2 of Chronic constriction injury-induced changes in circular RNA expression profiling of the dorsal root ganglion in a rat model of neuropathic pain
Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu & Zhiyao Wang
Additional file 2: Table S2. List of total circRNAs detected in the DRG of NC and CCI rats. RNA-seq was performed to profile circRNA expression in four paired DRG samples. A total of 13,172 circRNAs were detected in the L4–L5 DRG samples from the CCI and NC groups (4 mice per group).
Additional file 1 of Comparative chloroplast genome analyses of Amomum: insights into evolutionary history and species identification
Lu Gong, Xiaoxia Ding, Wan Guan, Danchun Zhang, Jing Zhang, Junqi Bai, Wen Xu, Juan Huang, Xiaohui Qiu, Xiasheng Zheng, Danyan Zhang, Shijie Li, Zhihai Huang & He Su
Additional file 1: Table S2.. Genbank accession numbers of DNA barcodes. Table S4. Results for one-vs-one calculation of Ka/Ks generated by KaKs_Calculator.
Additional file 13 of Exploration of the regulatory relationship between KRAB-Zfp clusters and their target transposable elements via a gene editing strategy at the cluster specific linker-associated sequences by CRISPR-Cas9
Yang Zhang, Fei He, Yanning Zhang, Qian Dai, Qintong Li, Jing Nan, Ruidong Miao & Bo Cheng
Additional file 13 Supplementary Table 5. sgRNA efficiency test in reporter system (raw data for Fig. 4B and D).
Additional file 16 of Exploration of the regulatory relationship between KRAB-Zfp clusters and their target transposable elements via a gene editing strategy at the cluster specific linker-associated sequences by CRISPR-Cas9
Yang Zhang, Fei He, Yanning Zhang, Qian Dai, Qintong Li, Jing Nan, Ruidong Miao & Bo Cheng
Additional file 16 Supplementary Table 8. Fingerprints of the 216 Human KRAB-ZFPs on chr19.
Additional file 1 of A CT-based nomogram for differentiating invasive fungal disease of the lung from bacterial pneumonia
Meilin Gong, Jingmei Xu, Kang Li, Ke Li, Yuwei Xia, Yang Jing, Jiafei Chen, Jing Li, Jing Yang, Mingshan Du, Wenjing Hou, Yuan Ou, Lian Li & Wei Chen
Additional file 1. On the orininal data of the study.
Additional file 12 of Genomic Architecture of Yield Performance of an Elite Rice Hybrid Revealed by its Derived Recombinant Inbred Line and Their Backcross Hybrid Populations
Fan Zhang, Conghe Zhang, Xiuqin Zhao, Shuangbing Zhu, Kai Chen, Guixiang Zhou, Zhichao Wu, Min Li, Tianqing Zheng, Wensheng Wang, Zhi Yan, Qinyong Fei, Zhikang Li, Jinjie Chen & Jianlong Xu
Additional file 12: Table S7. The function of 45 cloned yield related genes identified as the candidate genes for determining the performance of hybrid rice variety QYSM.
Additional file 4 of Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis
Liming Zhang, Yuxiang Wang, Li Qiu & Jian Wu
Additional file 4. The direct transcripts of the executed search strategies about MI and psoriasis.
Additional file 1 of Genome-wide association study uncovers major genetic loci associated with flowering time in response to active accumulated temperature in wild soybean population
Guang Yang, Wei Li, Chao Fan, Miao Liu, Jianxin Liu, Wenwei Liang, Ling Wang, Shufeng Di, Chao Fang, Haiyang Li, Guohua Ding, Yingdong Bi & Yongcai Lai
Additional file 1: Table S1. Prier used in this study. Table S2. List of 392 Glycine soja accessions and acumulated temperature zones. Table S3. 92 SNPs that significantly associated with flowering time in average across the two-year experiment (2020 and 2021). Table S4. The genes conresponding to the genomic regions surrounding ~50Kb of 92 SNPs that signficantly associated with flowering time in average in 2020 and 2021. Table S5. 28 candidate genes related to flowering...
Additional file 2 of Analysis of risk factors related to extremely and very preterm birth: a retrospective study
Xiaohong Ji, Chengqian Wu, Min Chen, Lili Wu, Ting Li, Zhijing Miao, Yan Lv & Hongjuan Ding
Supplementary Material 2
Additional file 9 of Exploration of the regulatory relationship between KRAB-Zfp clusters and their target transposable elements via a gene editing strategy at the cluster specific linker-associated sequences by CRISPR-Cas9
Yang Zhang, Fei He, Yanning Zhang, Qian Dai, Qintong Li, Jing Nan, Ruidong Miao & Bo Cheng
Additional file 9 Supplementary Table 1. All mouse and human KRAB-ZFP genes (information for Fig. 1 A and S1A)
Agricultural Crop- and Animal-specific Ammonia Emission Inventory
Yuyu Yang, Lei Liu, Pu Liu, Jia Ding, Hang Xu & Sheng Liu
All products (crop- and animal- specific NH3 emission inventories in the time span of 1961-2018) are provided in TIFF format at a spatial resolution of 0.5 degree by 0.5 degree (latitude by longitude) at figshare. The unit is kg N yr-1, stored in two folders (cropland and livestock).
Additional file 5 of ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao & Shengwei Zhu
Additional file 5. Detailed information of 30 overlap genes downregulated in ERF49 overexpression lines and upregulated after heat and BR treatment.
Additional file 11 of Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet
Preeti Dinesh Virwani, Lin Cai, Patrick Ka Kit Yeung, Gordon Qian, Yingxian Chen, Lei Zhou, Jason Wing Hon Wong, Yu Wang, Joshua Wing Kei Ho, Kui Kai Lau, Pei-Yuan Qian & Sookja Kim Chung
Additional file 11: Table S9. KEGG orthology IDs.
Additional file 2 of ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao & Shengwei Zhu
Additional file 2. Detailed information of genes downregulated in ERF49 overexpression lines after heat treatment.
Additional file 2 of ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao & Shengwei Zhu
Additional file 2. Detailed information of genes downregulated in ERF49 overexpression lines after heat treatment.
Additional file 3 of ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao & Shengwei Zhu
Additional file 3. Detailed information of genes upregulated after heat treatment.
Additional file 4 of Candidate genes screening based on phenotypic observation and transcriptome analysis for double flower of Prunus mume
Huanhuan Zhu, Yan Shi, Junwei Zhang, Manzhu Bao & Jie Zhang
Additional file 4.
Additional file 2 of De novo mutations within metabolism networks of amino acid/protein/energy in Chinese autistic children with intellectual disability
Wen-Xiong Chen, Bin Liu, Lijie Zhou, Xiaoli Xiong, Jie Fu, Zhi-Fang Huang, Ting Tan, Mingxi Tang, Jun Wang & Ya-Ping Tang
Additional file 2. Table S2: De novo mutations confirmed in 79 probands and their 2 siblings (Excel file) (dataset1). Table S6: De novo altering genes that involved in protein synthesis, pressure, energy metabolism, development, and amino acid metabolism (Excel file) (dataset2).
Additional file 3 of Candidate genes screening based on phenotypic observation and transcriptome analysis for double flower of Prunus mume
Huanhuan Zhu, Yan Shi, Junwei Zhang, Manzhu Bao & Jie Zhang
Additional file 3.
Additional file 4 of Lipidomics combined with transcriptomic and mass spectrometry imaging analysis of the Asiatic toad (Bufo gargarizans) during metamorphosis and bufadienolide accumulation
Bo Sun, Shan Jiang, Mingli Li, Yan Zhang, Yanyan Zhou, Xiaolu Wei, Hongjie Wang, Nan Si, Baolin Bian & Haiyu Zhao
Additional file 4: Table S4. After raw data filtering and examination of the sequencing error rate and GC content distribution.
Additional file 8 of FMO3 deficiency of duck leads to decreased lipid deposition and increased antibacterial activity
Xingzheng Li, Jianlou Song, Xuefeng Shi, Mingyi Huang, Lei Liu, Guoqiang Yi, Ning Yang, Guiyun Xu & Jiangxia Zheng
Additional file 8: Table S1. FMO3 mRNA expression in the CL and TH groups.
Affiliations
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Jilin University755
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Chinese Academy of Medical Sciences & Peking Union Medical College538
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Shanghai Jiao Tong University470
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Sichuan University451
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Zhejiang University434
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Fudan University433
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Chinese Academy of Sciences385
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Sun Yat-sen University379
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University of Chinese Academy of Sciences356
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Huazhong University of Science and Technology345