Objective: On 11 March 2011, the Great East Japan Earthquake struck off Japan. Although some studies showed that the earthquake increased the risk of pneumonia death, no study reported whether and how much tsunami increased the risk. We examined the risk for pneumonia death after the earthquake/tsunami. Design: This is an ecological study. Setting: Data on population and pneumonia deaths obtained from the Vital Statistics 2010 and 2012, National Census 2010 and Basic Resident Register...

We conducted epigenotype-phenotype analysis in 84 patients with methylation defects of the DMRs on the GNAS locus classified into three groups according to the etiologies and methylation defect patterns of the DMRs on the GNAS locus.

We conducted epigenotype-phenotype analysis in 84 patients with methylation defects of the DMRs on the GNAS locus classified into three groups according to the etiologies and methylation defect patterns of the DMRs on the GNAS locus.

Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in the amplification of MARV outbreaks in African countries. The high fatality rate of up to 90% demands the broad study of MARV diseases (MVD) that correspond with MARV...

Additional file 2: Table S2. DNA variant profile (Case #2).

Additional file 1: Table S1. DNA variant profile (Case #1).

Additional file 4: Table S4. Mutational signature of the single base substitution.

Although a guideline for reporting the results of community-based participatory research (CBPR) was published in 2010, the impact on the quality of reporting a CBPR on smoking cessation is unknown. Here we provide the raw data of a systematic review that assessed the impact of a 2010 community-based participatory research reporting guideline. on the quality of reporting a CBPR on smoking cessation. Specifically, we searched the MEDLINE, Embase, the Cochrane Central Register for Controlled Trials...

Additional file 3: Table S3. Mutational signature of the single base substitutions (SBS).

Additional file 2: Table S2. DNA variant profile (Case #2).

Additional file 1: Table S1. DNA variant profile (Case #1).

Axial spondylometaphyseal dysplasia(axial SMD) is associated with early-onset retinal dystrophy and various skeletal dysplasias of varying severity. NEK1 is the causative gene for short rib polydactyly syndrome and axial SMD. Here, we report a case of siblings with juvenile retinitis pigmentosa (RP) and NEK1 variants not associated with systemic disorders. The patients were a 7-year-old-girl and a 9-year-old boy with RP, who were followed for 9 years. Whole exome sequencing (WES) was performed on the...

Additional file 1: Table S1. Quantitative RT-PCR analysis.

Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in the amplification of MARV outbreaks in African countries. The high fatality rate of up to 90% demands the broad study of MARV diseases (MVD) that correspond with MARV...

Axial spondylometaphyseal dysplasia(axial SMD) is associated with early-onset retinal dystrophy and various skeletal dysplasias of varying severity. NEK1 is the causative gene for short rib polydactyly syndrome and axial SMD. Here, we report a case of siblings with juvenile retinitis pigmentosa (RP) and NEK1 variants not associated with systemic disorders. The patients were a 7-year-old-girl and a 9-year-old boy with RP, who were followed for 9 years. Whole exome sequencing (WES) was performed on the...

We conducted epigenotype-phenotype analysis in 84 patients with methylation defects of the DMRs on the GNAS locus classified into three groups according to the etiologies and methylation defect patterns of the DMRs on the GNAS locus.

We conducted epigenotype-phenotype analysis in 84 patients with methylation defects of the DMRs on the GNAS locus classified into three groups according to the etiologies and methylation defect patterns of the DMRs on the GNAS locus.

Additional file 1: Table S1. Quantitative RT-PCR analysis.

Additional file 3: Table S3. Mutational signature of the single base substitutions (SBS).

Additional file 4: Table S4. Mutational signature of the single base substitution.