71 Works

The interplay of wind and uplift facilitates over-water flight in facultative soaring birds

Elham Nourani, Gil Bohrer, Paolo Becciu, Richard O Bierregaard, Olivier Duriez, Jordi Figuerola, Laura Gangoso, Sinos Giokas, Hiroyoshi Higuchi, Christina Kassara, Olga Kulikova, Nicolas Lecomte, Flavio Monti, Ivan Pokrovsky, Andrea Sforzi, Jean-François Therrien, Nikos Tsiopelas, Wouter MG Vansteelant, Duarte S Viana, Noriyuki M Yamaguchi, Martin Wikelski & Kamran Safi
Flying over the open sea is energetically costly for terrestrial birds. Despite this, over-water journeys of many birds, sometimes hundreds of kilometers long, are uncovered by bio-logging technology. To understand how these birds afford their flights over the open sea, we investigated the role of atmospheric conditions, specifically wind and uplift, in subsidizing over-water flight at the global scale. We first established that ∆T, the temperature difference between sea surface and air, is a meaningful...

Influence of YES1 kinase and tyrosine phosphorylation on the activity of OCT1

Muhammad Erfan Uddin, Dominique Garrison, Kyeongmin Kim, Yan Jin, Eric Eisenmann, Kevin Huang, Alice Gibson, Zeping Hu, Alex Sparreboom & Shuiying Hu
Organic cation transporter 1 (OCT1) is a transporter that regulates the hepatic uptake and subsequent elimination of diverse cationic compounds. Although OCT1 has been involved in drug-drug interactions and causes pharmacokinetic variability of many prescription drugs, details of the molecular mechanisms that regulate the activity of OCT1 remain incompletely understood. Based on an unbiased phospho-proteomics screen, we identified OCT1 as a tyrosine-phosphorylated transporter, and functional validation studies using genetic and pharmacological approaches revealed that OCT1...

Potential local adaptation in populations of invasive reed canary grass (Phalaris arundinacea) across an urbanization gradient

Stephen Hovick, Leah Weston, Kali Mattingly & Charles Day
Urban stressors represent strong selective gradients that can elicit evolutionary change, especially in non-native species that may harbor substantial within-population variability. To test whether urban stressors drive phenotypic differentiation and influence local adaptation, we compared stress responses of populations of a ubiquitous invader, reed canary grass (Phalaris arundinacea). Specifically, we quantified responses to salt, copper, and zinc additions by reed canary grass collected from four populations spanning an urbanization gradient (natural, rural, moderate urban and...

An integrated population model to project viability of a northern bobwhite population in Ohio [DATA]

Connor Rosenblatt
Increased variation in interannual weather due to climate change can exert a powerful influence on the population dynamics of a species. Understanding the influence of severe weather is important for managing weather-sensitive species. While best management practices target vital rates that are affected by weather, focusing on a single vital rate may not be sufficient if other vital rates are secondarily limiting. A comprehensive modeling framework to forecast future population dynamics while incorporating weather scenarios...

Phylogeographic analysis of shrubby beardtongues reveals range expansions during the Last Glacial Maximum and implicates the Klamath Mountains as a hotspot for hybridization

Benjamin Stone & Andrea Wolfe
Quaternary glacial cycles often altered species’ geographic distributions, which in turn altered the geographic structure of species’ genetic diversity. In many cases, glacial expansion forced species in temperate climates to contract their ranges and reside in small pockets of suitable habitat (refugia), where they were likely to interact closely with other species, setting the stage for potential gene exchange. These introgression events, in turn, would have degraded species boundaries, making the inference of phylogenetic relationships...

Functional traits reveal the dominant drivers of long‐term community change across a North American Great Lake

James Sinclair, Michael Fraker, James Hood, Kenneth Frank, Mark DuFour, Ann Marie Gorman & Stuart Ludsin
The datasets here were used to determine annual sentinel fish species and trait composition in Lake Erie's western and central basins during 1969-2018 in relation to multiple anthropogenic stressors. Here, we provide three datasets, which are used in the paper by Sinclair et al. titled: "Functional traits reveal the dominant drivers of long-term community change across a North American Great Lake". Each dataset is provided as a separate tab in a single Excel worksheet. The...

Expository and narrative discourse summary statistics and demographic information for adolescents with and without traumatic brain injury

Gavin Collins, Jennifer Lundine & Eloise Kaizar
Purpose: Generalized linear mixed models (GLMM) and Bayesian methods together provide a framework capable of handling a wide variety of complex data commonly encountered across the communication sciences. Using language sample analysis (LSA), we demonstrate the utility of these methods in answering specific questions regarding the differences between discourse patterns of children who have experienced a traumatic brain injury (TBI), as compared to those with typical development (TD). Methods: Language samples were collected from 55...

Coupon model for novel rotating-disc rheometry method

Erin Gloag
The model for the coupons was designed in SolidWorks (Dassault Systèmes); refer to supplementary file 1. Coupons were 3D printed using a Prime 30 PolyJet 3D printer (Objet, Stratasys) using RGD720 photopolymer for the printing material (Stratasys). The coupon was printed at a resolution of 0.0008 inches. The coupon surface was sanded used P300 sandpaper to create a rougher surface for bacteria to attach. Prior to inoculating, coupons were sterilized in 70% ethanol.

Data from: Accuracy in the prediction of disease epidemics when ensembling simple but highly correlated models

Denis Shah, Erick De Wolf, Pierce Paul & Laurence Madden
Ensembling combines the predictions made by individual component base models with the goal of achieving a predictive accuracy that is better than that of any one of the constituent member models. Diversity among the base models in terms of predictions is a crucial criterion in ensembling. However, there are practical instances when the available base models produce highly correlated predictions, because they may have been developed within the same research group or may have been...

Effects of wildfire and Paulownia tomentosa on native tree regeneration

Roger Williams & Haibin Wang
A wildfire occurred in Shawnee State Forest located in southern Ohio that consumed 1215 hectares. Based on earlier forest inventories it was known that paulownia (Paulownia tomentosa), a non-native invasive tree species, occurred in the forest. The objective of this study was to determine if paulownia heavily colonized areas two years after the fire where the burn occurred, and if its presence had a negative impact on the regeneration (<137 cm height) of native species—red...

Influential factors of environmental behavior to reduce air pollution: integrating theories of planned behavior and psychological distance

Yang Cheng, Changlin Ao, Biqi Mao & Lishan Xu
Exploring the incentive mechanism of public participation is the key to the implementation of sustainable policies in China. This study related the constructs of psychological distance (PD), the theory of planned behavior (TPB) and willingness to pay (WTP) to examine the influential factors of environmental behaviors to prevent air pollution. The contingent valuation method was applied to demonstrate pro-environmental endeavors by measuring WTP and the structural equation model was used to clarify the effects between...

Aloin decelerates the progression of hepatocellular carcinoma through circ_0011385/miR-149-5p/WT1 axis

Dazhi Fu, Qiang Ji, Chunxiao Wang, Lei Yu & Rui Yu
CircRNA/miRNA/mRNA axis has been reported to play crucial regulatory roles in multiple cancers, including hepatocellular carcinoma (HCC). In addition, recent investigations revealed that aloin exerted anti-tumor functions in HCC. However, the underlying mechanism of aloin on anti-tumor functions in HCC remained elusive. Therefore, this study aimed to investigate whether circRNA/miRNA/mRNA axis medicated the anti-tumor effect of aloin in HCC. Cell viability, invasion, apoptosis and autophagy were accessed by cell counting kit-8 (CCK-8), transwell invasion assay,...

Prenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status

Yassaman Vafai, Edwina H. Yeung, Rajeshwari Sundaram, Melissa M. Smarr, Nicole Gerlanc, William A. Grobman, Daniel Skupski, Edward K. Chien, Stefanie N. Hinkle, Roger B. Newman, Deborah A. Wing, Angela C. Ranzini, Anthony Sciscione, Jagteshwar Grewal, Cuilin Zhang & Katherine L. Grantz
The association between obesity (body mass index (BMI) ≥ 30 kg/m2) and pattern of medication use during pregnancy in the United States is not well-studied. Higher pre-pregnancy BMI may be associated with increases or decreases in medication use across pregnancy as symptoms (e.g. reflux) or comorbidities (e.g. gestational diabetes) requiring treatment that may be associated with higher BMI could also change with advancing gestation. To determine whether prenatal medication use, by the number and types...

Prenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status

Yassaman Vafai, Edwina H. Yeung, Rajeshwari Sundaram, Melissa M. Smarr, Nicole Gerlanc, William A. Grobman, Daniel Skupski, Edward K. Chien, Stefanie N. Hinkle, Roger B. Newman, Deborah A. Wing, Angela C. Ranzini, Anthony Sciscione, Jagteshwar Grewal, Cuilin Zhang & Katherine L. Grantz
The association between obesity (body mass index (BMI) ≥ 30 kg/m2) and pattern of medication use during pregnancy in the United States is not well-studied. Higher pre-pregnancy BMI may be associated with increases or decreases in medication use across pregnancy as symptoms (e.g. reflux) or comorbidities (e.g. gestational diabetes) requiring treatment that may be associated with higher BMI could also change with advancing gestation. To determine whether prenatal medication use, by the number and types...

Immune implication of FAM83D gene in hepatocellular carcinoma

Tao Meng, Zhong Tong, Ming-Ya Yang, Yan Zhang, Yu Liu, Zhen-Zhen Wang, Li-Xin Zhu & Jin Wu
FAM83D has been demonstrated to contribute to tumorigenesis. However, its immune effects in hepatocellular carcinoma (HCC) have not been reported. This study aimed to identify the immune role of FAM83D in HCC. FAM83D was over-expressed in HCC and contributed to poor prognosis according to the results of data analysis based on The Cancer Genome Atlas (TCGA). Afterward, the levels of immune cells infiltration were found to be correlated with the expression level of FAM83D in...

Circular RNA Circ_0005564 promotes osteogenic differentiation of bone marrow mesenchymal cells in osteoporosis

Zitao Liu, Qiyu Liu, Shanchuang Chen, Haitao Su & Tao Jiang
Circular RNA (CircRNA) plays a potential role in bone formation. We aimed to study the circRNAs expression profiles and their functions in osteogenic differentiation of human bone marrow stromal cells (BMSCs). Firstly, we established osteogenic differentiation of BMSCs displaying increased mRNA expression of osteogenic differentiation marker (RUNX2, OPN, and OCN), increased ALP activity and protein expression, and increased mineralized nodules formation, as well as morphological alteration. Then, we employed high-throughput sequencing to analyze circRNA expression...

Diversification of a polyploid complex: the biogeography and acoustic communication evolution of North American gray treefrogs throughout the Quaternary

William Booker, Emily Lemmon, Alan Lemmon, Margaret Ptacek, Alyssa Hassinger, Johannes Schul & H. Carl Gerhardt
Polyploid speciation and whole genome duplications are major drivers of biological diversity. After polyploid species are formed, the interactions between diploid and polyploid lineages may generate additional diversity in novel cytotypes and phenotypes. In anurans, mate choice by acoustic communication is the primary method by which individuals identify their own species and assess suitable mates. As such, the evolution of acoustic signals is an important mechanism for contributing to reproductive isolation and diversification in this...

Mammals on mountainsides revisited: trait-based tests of assembly reveal the importance of abiotic filters

Brooks Kohli, Richard Stevens, Eric Rickart & Rebecca Rowe
Aim: Mountains provide uniquely informative systems for examining how biodiversity is distributed and identifying the causes of those patterns. Elevational patterns of species richness are well-documented for many taxa but comparatively few studies have investigated patterns in multiple dimensions of biodiversity along mountainsides, which can reveal the underlying processes at play. Here, we use trait-based diversity patterns to determine the role of abiotic filters and competition in the assembly of communities of small mammals across...

Phenotype data, genotype input files, and scripts related to adaptation in wild house mice from Western North America

Kathleen Ferris, Andreas Chavez, Taichi Suzuki, Megan Phifer-Rixey, Ke Bi, Michael Nachman & Elizabeth Beckman
Parallel changes in genotype and phenotype in response to similar selection pressures in different populations provide compelling evidence of adaptation. House mice (Mus musculus domesticus) have recently colonized North America and are found in a wide range of environments. Here we measure phenotypic and genotypic differentiation among house mice from five populations sampled across 21° of latitude in western North America, and we compare our results to a parallel latitudinal cline in eastern North America....

The Chemical Reaction Network Toolbox, Windows Version

Martin Feinberg, Phillipp Ellison, Haixia Ji & Daniel Knight
The Chemical Reaction Network Toolbox provides computer-supported assistance for the analysis of the behavior of complex chemical reaction networks. Its use and theoretical underpinnings are described, for example, in the monograph "Foundations of Chemical Reaction Network Theory" by Martin Feinberg, published in 2019 by Springer-Nature. The download is a zip file containing the Toolbox, a user's guide, and some sample network files.

Reevaluating the species status of the southern ghost pipe, Monotropa brittonii (Ericaceae)

Ashley Keesling, John Freudenstein & Michael Broe
Relationships among members of Ericaceae subfamily Monotropoideae have been notoriously difficult to resolve due to convergent evolution in these parasitic plants. All species in this subfamily are fully mycoheterotrophic, meaning they obtain nutrients by parasitizing fungi rather than through photosynthesis. Here, we examine relationships and host specificity in one of the most widespread species in this subfamily, Monotropa uniflora L. We use several lines of evidence to investigate whether there is support for recognizing a...

Genomic signatures of inbreeding and mutation load in a threatened rattlesnake

Alexander Ochoa & H. Lisle Gibbs
Theory predicts that threatened species living in small populations will experience high levels of inbreeding that will increase their genetic load, but recent work suggests that the impact of load may be minimized by purging resulting from long-term population bottlenecks. Empirical studies that examine this idea using genome-wide estimates of inbreeding and genetic load in threatened species are limited. Here we use individual genome resequencing data to compare levels of inbreeding, levels of genetic load...

Adaptation without specialization early in a host shift: fecundity data

Rafael Rodriguez, Thomas Wood, Frank Stearns, Robert Snyder, Kelley Tilmon, Michael Cast, Randy Hunt & Reginald Cocroft
Students of speciation debate the role of performance trade-offs across different environments early in speciation. We tested for early performance trade-offs with a host shift experiment using a member of the Enchenopa binotata species complex of treehoppers (Hemiptera: Membracidae). In this clade of plant-feeding insects, different species live on different host plants and exhibit strong behavioral and physiological host specialization. After five generations, the experimental host shifts resulted either in no adaptation or in adaptation...

Indoor dust as a matrix for surveillance of COVID-19 outbreaks

Nicole Renninger, Nick Nastasi, Ashleigh Bope, Samuel Cochran, Sarah Haines, Neeraja Balasubrahmaniam, Katelyn Stuart, Aaron Bivins, Kyle Bibby, Natalie Hull & Karen Dannemiller
Ongoing disease surveillance is a critical tool to mitigate viral outbreaks, especially during a pandemic. Environmental monitoring has significant promise even following widespread vaccination among high-risk populations. The goal of this work is to demonstrate molecular SARS-CoV-2 monitoring in bulk floor dust and related samples as a proof-of-concept of a non-invasive environmental surveillance methodology for COVID-19 and potentially other viral diseases. Surface swab, passive sampler, and bulk floor dust samples were collected from rooms of...

Data for: The long-term impacts of deer herbivory in determining temperate forest stand and canopy structural complexity

Samuel Reed, Alejandro Royo, Alexander Fotis, Kathleen Knight, Charles Flower & Peter Curtis
1. Ungulates place immense consumptive pressure on forest vegetation globally, leaving legacies of reduced biodiversity and simplified vegetative structure. However, what remains unresolved is whether browse-induced changes occurring early in succession ultimately manifest themselves in the developed forest canopy. Understanding the development and persistence of these legacies is critical as canopy structure is an important determinant of forest ecosystem functions like carbon sequestration and wildlife habitat. 2. We measured how white-tailed deer (Odocoileus virginianus) browse...

Registration Year

  • 2021

Resource Types

  • Dataset


  • The Ohio State University
  • Zhejiang University
  • Huazhong University of Science and Technology
  • Sun Yat-sen University
  • Jilin University
  • Sichuan University
  • Capital Medical University
  • Indiana University Bloomington
  • Southern Medical University
  • Peking University First Hospital