2 Works

Data from: The phylogenetic utility and functional constraint of microRNA flanking sequences

Nathan J. Kenny, Yung Wa Sin, Alexander Hayward, Jordi Paps, Ka Hou Chu & Jerome H. L. Hui
MicroRNAs (miRNAs) have recently risen to prominence as novel factors responsible for post-transcriptional regulation of gene expression. miRNA genes have been posited as highly conserved in the clades in which they exist. Consequently, miRNAs have been used as rare genome change characters to estimate phylogeny by tracking their gain and loss. However, their short length (21–23 bp) has limited their perceived utility in sequenced-based phylogenetic inference. Here, using reference taxa with established phylogenetic relationships, we...

Data from: Ancestral whole genome duplication in the marine chelicerate horseshoe crabs

Nathan J. Kenny, Ka Wo Chan, Wenyan Nong, Zhe Qu, Ignacio Maeso, Ho Yin Yip, Ting Fung Chan, Hoi Shan Kwan, Peter W. H. Holland, Ka Hou Chu & Jerome H. L. Hui
Whole-genome duplication (WGD) results in new genomic resources that can be exploited by evolution for rewiring genetic regulatory networks in organisms. In metazoans, WGD occurred before the last common ancestor of vertebrates, and has been postulated as a major evolutionary force that contributed to their speciation and diversification of morphological structures. Here, we have sequenced genomes from three of the four extant species of horseshoe crabs—Carcinoscorpius rotundicauda, Limulus polyphemus and Tachypleus tridentatus. Phylogenetic and sequence...

Registration Year

  • 2015

Resource Types

  • Dataset


  • Chinese University of Hong Kong
  • University of Oxford
  • Pablo de Olavide University
  • Stockholm University