3 Works

Dynamic evolution of euchromatic satellites on the X chromosome in Drosophila melanogaster and the simulans clade

J.S. Sproul, D.E. Khost, D.G. Eickbush, S. Negm, X. Wei, I. Wong & A.M. Larracuente
ABSTRACTSatellite DNAs (satDNAs) are among the most dynamically evolving components of eukaryotic genomes and play important roles in genome regulation, genome evolution, and speciation. Despite their abundance and functional impact, we know little about the evolutionary dynamics and molecular mechanisms that shape satDNA distributions in genomes. Here we use high-quality genome assemblies to study evolutionary dynamics of two complex satDNAs, Rsp-like and 1.688 gm/cm3, in Drosophila melanogaster and its three nearest relatives in the simulans...

Medicare Shared Savings Program and readmission rate among ischemic stroke patients

Yeunkyung Kim, Laurent Glance, Robert Holloway & Yue Li
Objective Hospitals participating in the Medicare Shared Savings Program (MSSP) share with the Centers for Medicare and Medicaid Services (CMS) the savings generated by reducing readmissions. Our aim was to determine whether MSSP is associated with changes in readmissions and mortality for Medicare patients hospitalized with ischemic stroke, and whether MSSP has a different impact on safety-net hospitals (SNHs) compared to non-SNHs. Methods This study was based on the CMS Hospital Compare data for risk-standardized...

Data from: Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure

Matthew McGraw, So‐Young Kim, Carl W. White & Livia A. Veress
RATIONALE: Nitrogen mustard (NM) is a highly toxic alkylating agent. It is classified as chemical threat due to its potential use as a warfare agent. When inhaled, mustard exposure can cause both acute and chronic lung injury. The aims of this study are to develop an in vitro culture system for modeling mustard-induced airway injury and to identify growth factors contributing to airway pathology. METHODS: Primary human bronchial epithelial cells co-cultured with primary human pulmonary...

Registration Year

  • 2020

Resource Types

  • Dataset


  • University of Rochester Medical Center
  • University of Rochester
  • University of Colorado Denver