7 Works

Data from: Factors associated with first- versus second-generation long-acting antipsychotics prescribed under ordinary clinical practice in Italy

Giovanni Ostuzzi, Maria Angela Mazzi, Samira Terlizzi, Federico Bertolini, Andrea Aguglia, Francesco Bartoli, Paola Bortolaso, Camilla Callegari, Mariarita Caroleo, Giuseppe Carrà, Mariangela Corbo, Armando D'agostino, Chiara Gastaldon, Claudio Lucii, Fabio Magliocco, Giovanni Martinotti, Michela Nosé, Edoardo Giuseppe Ostinelli, Davide Papola, Marco Piccinelli, Alberto Piccoli, Marianna Purgato, Tommaso Tabacchi, Giulia Turrini, Mirella Ruggeri … & Armando D’Agostino
Background. For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, a broader and earlier use of LAIs, particularly second-generation LAIs, has been emphasized. To date, few studies attempted to frame how this change in prescribing took place in real-world practice. Therefore, this study aimed to describe the clinical features of patients prescribed with LAIs, and to explore possible prescribing...

Data from: Clinical spectrum of STX1B-related epileptic disorders

Stefan Wolking, Patrick May, Davide Mei, Rikke S. Møller, Simona Balestrini, Katherine L. Helbig, Cecilia Desmettre Altuzarra, Nicolas Chatron, Charu Kaiwar, Katharina Stoehr, Peter Widdess-Walsh, Bryce A. Mendelsohn, Adam Numis, Maria R. Cilio, Wim Van Paesschen, Lene L. Svendsen, Stephanie Oates, Elaine Hughes, Sushma Goyal, Kathleen Brown, Margarita Sifuentes Saenz, Thomas Dorn, Hiltrud Muhle, Alistair T. Pagnamenta, Dimitris V. Vavoulis … & Julian Schubert
Objective: The aim of this study was to expand the spectrum of epilepsy syndromes related to STX1B, encoding the presynaptic protein syntaxin-1B, and establish genotype-phenotype correlations by identifying further disease-related variants. Methods: We used next generation sequencing in the framework of research projects and diagnostic testing. Clinical data and EEGs were reviewed, including already published cases. To estimate the pathogenicity of the variants, we used established and newly developed in silico prediction tools. Results: We...

Data from: Signatures of selection and environmental adaptation across the goat genome post-domestication

Licia Colli, Marco Milanesi, Andrea Talenti, Francesca Bertolini, Minhui Chen, Alessandra Crisà, Kevin Daly, Marcello Del Corvo, Bernt Guldbrandtsen, Johannes A. Lenstra, Ben D. Rosen, Elia Vajana, Gennaro Catillo, Stéphane Joost, Ezequiel Luis Nicolazzi, Estelle Rochat, Max F. Rothschild, Bertrand Servin, Tad S. Sonstegard, Roberto Steri, Curtis P. Van Tassel, Paolo Ajmone-Marsan, Paola Crepaldi, Alessandra Stella & AdaptMap Consortium
Background: Since goat was domesticated 10,000 years ago, many factors have contributed to the differentiation of goat breeds and these are classified mainly into two types: (i) adaptation to different breeding systems and/or purposes and (ii) adaptation to different environments. As a result, approximately 600 goat breeds have developed worldwide; they differ considerably from one another in terms of phenotypic characteristics and are adapted to a wide range of climatic conditions. In this work, we...

Data from: Protoporphyrin-based eggshell pigmentation is associated with female plumage colouration and predicts offspring sex ratio in the barn swallow

Margherita Corti, Andrea Romano, Alessandra Costanzo, Alexandra B. Bentz, Kristen Navara, Marco Parolini, Nicola Saino, Diego Rubolini & Kristen J. Navara
Inter- and intraspecific variation in eggshell colouration has long fascinated evolutionary biologists. Among species, such variation may accomplish different functions, the most obvious of which is camouflage and background matching. Within species, it has been proposed that inter-female variation in eggshell pigmentation patterns can reflect egg, maternal or paternal traits and hence may provide cues to conspecifics about egg, maternal or paternal phenotypic quality. However, the relationship between protoporphyrin-based eggshell pigmentation and egg or maternal/paternal...

Data from: Deciphering the drivers of negative species-genetic diversity correlation in Alpine amphibians

Alexis Marchesini, Cristiano Vernesi, Andrea Battisti & Gentile Francesco Ficetola
The evolutionary and ecological importance of neutral and adaptive genetic diversity is widely recognized. Nevertheless, genetic diversity is rarely assessed for conservation planning, which often implicitly assumes a positive correlation between species and genetic diversity. Multiple drivers can cause the co-variation between the genetic diversity of one species and the richness of the whole communities, and explicit tests are needed to identify the processes that can determine species-genetic diversity correlations (SGDC). Here we tested whether...

Data from: Stress in biological invasions: introduced invasive grey squirrels increase physiological stress in native Eurasian red squirrels

Francesca Santicchia, Ben Dantzer, Freya Van Kesteren, Rupert Palme, Adriano Martinoli, Nicola Ferrari & Lucas Armand Wauters
1. Invasive alien species can cause extinction of native species through processes including predation, interspecific competition for resources, or disease-mediated competition. Increases in stress hormones in vertebrates may be associated with these processes and contribute to the decline in survival or reproduction of the native species. 2. Eurasian red squirrels (Sciurus vulgaris) have gone extinct across much of the British Isles and parts of Northern Italy following the introduction of North American invasive grey squirrels...

Data from: Matching geographical assignment by stable isotopes with African non-breeding sites of Barn swallows Hirundo rustica tracked by geolocation

Nina Seifert, Roberto Ambrosini, Luana Bontempo, Frederica Camin, Felix Liechti, Diego Rubolini, Chiara Scandolara, Nicola Saino, Steffen Hahn & Federica Camin
Knowledge on whereabouts within the annual cycle of migratory species is prerequisite for many aspects in ecology and biological conservation. Spatial assignments of stable isotopes archived in tissues allows for later inference on sites where the specific tissue had been grown.. It has been rarely tested whether spatial assignments match directly tracked non-breeding residences, especially for migratory songbirds. We here compare assignments of stable isotopes from feathers of Palaearctic Barn swallows Hirundo rustica with their...

Registration Year

  • 2018

Resource Types

  • Dataset


  • University of Milan
  • University of Antwerp
  • University of Insubria
  • University of Milano-Bicocca
  • University of Verona
  • University of Padua
  • Massachusetts General Hospital
  • Hvidovre Hospital
  • University of Michigan-Ann Arbor
  • Children's Hospital Colorado