220 Works

Methyl-Sensitive Amplification Polymorphism (MSAP) Analysis Provides Insights into the DNA Methylation Underlying Heterosis in Kenaf (Hibiscus Cannabinus L.) Drought Tolerance

Dengjie Luo, Shan Cao, Zengqiang Li, Meiqiong Tang, Caijin Wang, Enerand Mackon, Zhen Huang, Jiao Pan, Xia Wu, Qijing Wu, Hui Zhang, Renxue Li, Xin Li, Ru Li & Peng Chen
Kenaf (Hibiscus cannabinus L.) is an industrial fiber crop with significant heterosis and tolerance to abiotic stresses. However, the mechanism underlying heterosis in kenaf under drought conditions is completely unknown. In this study, F1 hybrids were remarkably tolerant to drought stress. Through methylation-sensitive amplification polymorphism (MSAP) analysis, we highlighted that total DNA methylation level under drought decreased by 11.2% in F1 and increased by 29.7% and 13.1% in parents CP079 and CP071, respectively. Unlike parents,...

Anatexis of late Neoarchean-Early Paleoproterozoic and late Paleoproterozoic garnet-bearing leucogranite from the Khondalite Belt in the North China Craton

Qiang Shi, Zhong-Yuan Xu, Guo-Chun Zhao, Ding Ding, Guang-Wei Liu, Zhong-Hai Zhao, Jing-Yu Yu, Chen Li, Li-Qiang Bai, Yao Wang, Bing Guo, Kai Zhang & Chun-Feng Liu
Two episodes of late Neoarchean-early Paleoproterozoic and late Paleoproterozoic garnet-bearing leucogranite, named the Baotou and Jining–Liangcheng garnet-bearing leucogranite are recognized from the Khondalite Belt in the North China Craton. Geochemical studies show that garnet-bearing leucogranite has high Al2O3 content and FeOT/MgO ratio, with a large variation in the CaO content and K2O/Na2O ratio. Additionally, the garnet-bearing leucogranite is enriched in light rare earth elements and large ion lithophile elements and depleted in Nb, Ta, P,...

Additional file 1 of COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

Wei-Yu Chi, Yen-Der Li, Hsin-Che Huang, Timothy En Haw Chan, Sih-Yao Chow, Jun-Han Su, Louise Ferrall, Chien-Fu Hung & T.-C. Wu
Additional file 1: Table S1. Vaccine effectiveness against viral variants. Studies of vaccine effectiveness against viral variants. Related to Table 2.

Additional file 2 of COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

Wei-Yu Chi, Yen-Der Li, Hsin-Che Huang, Timothy En Haw Chan, Sih-Yao Chow, Jun-Han Su, Louise Ferrall, Chien-Fu Hung & T.-C. Wu
Additional file 2: Table S2. Vaccine efficacy and effectiveness in children and adolescents

Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits

Zhangjun Wang, Qingfeng Li, Caixia Liu, Fenglou Liu, Nali Xu, Mingming Yao, Huixia Yu, Yanqing Wang, Jiajing Chen, Shuangyu Bai, Jingxin Yang, Gang Sun, Jiaohui Long, Yalei Fan, Ling Kang, Hongxia Li, Xiaogang Zhang & Shengxiang Liu
Abstract Hordeum californicum (H. californicum, 2n=2X=14, HcHc), one of the wild relatives of wheat (Triticum aestivum L.), harbors many desirable genes and is a potential genetic resource for wheat improvement. In this study, an elite line ND646 was selected from a BC4F5 population, which was developed using 60Co-γ irradiated wheat-H. californicum disomic addition line WJ28-1 (DA6Hc) as the donor parent and Ningchun 4 as the recurrent parent. ND646 was identified as a novel wheat-H. californicum...

Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits

Zhangjun Wang, Qingfeng Li, Caixia Liu, Fenglou Liu, Nali Xu, Mingming Yao, Huixia Yu, Yanqing Wang, Jiajing Chen, Shuangyu Bai, Jingxin Yang, Gang Sun, Jiaohui Long, Yalei Fan, Ling Kang, Hongxia Li, Xiaogang Zhang & Shengxiang Liu
Abstract Hordeum californicum (H. californicum, 2n=2X=14, HcHc), one of the wild relatives of wheat (Triticum aestivum L.), harbors many desirable genes and is a potential genetic resource for wheat improvement. In this study, an elite line ND646 was selected from a BC4F5 population, which was developed using 60Co-γ irradiated wheat-H. californicum disomic addition line WJ28-1 (DA6Hc) as the donor parent and Ningchun 4 as the recurrent parent. ND646 was identified as a novel wheat-H. californicum...

Additional file 1 of Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease

Qian Zhu, Min Qin, Zixian Wang, Yonglin Wu, Xiaoping Chen, Chen Liu, Qilin Ma, Yibin Liu, Weihua Lai, Hui Chen, Jingjing Cai, Yemao Liu, Fang Lei, Bin Zhang, Shuyao Zhang, Guodong He, Hanping Li, Mingliang Zhang, Hui Zheng, Jiyan Chen, Min Huang & Shilong Zhong
Additional file 1: Table S1. Baseline characteristics on death and MACE risks. Table S2. Baseline characteristics on LVEF and LVMI. Table S3. Relationship between metabolites and death risk. Table S4. Relationship between metabolites and MACE risk. Table S5. Multivariate Cox proportional hazards model for clinical outcomes. Table S6. Spearman correlation analysis between clinical factors and those metabolites associated with death risk. Table S7. Spearman correlation analysis between clinical factors and those metabolites associated with death...

Remote consent approaches for mobile phone surveys of non-communicable disease risk factors in Colombia and Uganda: A randomized study

Joseph Ali, Madhuram Nagarajan, Erisa Sabakaki Mwaka, Elizeus Rutebemberwa, Andres I. Vecino-Ortiz, Angelica Tórres Quintero, Mariana Rodriguez-Patarroyo, Vidhi Maniar, Gulam Muhammed Al Kibria, Alain B. Labrique, George W Pariyo & Dustin G. Gibson
Introduction: Automated mobile phone surveys (MPS) can be used to collect public health data of various types to inform health policy and programs globally. One challenge in administering MPS is identification of an appropriate and effective participant consent process. This study investigated the impact of different survey consent approaches on participant disposition (response characteristics and understanding of the purpose of the survey) within the context of an MPS that measured noncommunicable disease (NCD) risk factors...

sj-xlsx-1-npx-10.1177_1934578X221131126 - Supplemental material for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology

Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang & Xiao Liu
Supplemental material, sj-xlsx-1-npx-10.1177_1934578X221131126 for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology by Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang and Xiao Liu in Natural Product Communications

sj-xlsx-3-npx-10.1177_1934578X221131126 - Supplemental material for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology

Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang & Xiao Liu
Supplemental material, sj-xlsx-3-npx-10.1177_1934578X221131126 for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology by Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang and Xiao Liu in Natural Product Communications

Additional file 2 of Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues

Emily R. Penick, Nicholas W. Bateman, Christine Rojas, Cuauhtemoc Magana, Kelly Conrads, Ming Zhou, Brian L. Hood, Guisong Wang, Niyati Parikh, Ying Huang, Kathleen M. Darcy, Yovanni Casablanca, Paulette Mhawech-Fauceglia, Thomas P. Conrads & G. Larry Maxwell
Additional file 2: Table S1. Proteins significantly altered between post versus pre-NACT tissues (LIMMA p-value<0.01). Table S2. Proteins significantly altered between R1 versus R0 patients in pre-NACT tissues (LIMMA p-value<0.05). Table S3. Significantly (LIMMA p<0.05) co-altered proteins between pre-NACT tumors from patients with any level of residual disease vs R0 patients from an independent ovarian cancer cohort (CPTAC 2016) that exhibit highly correlated abundance trends with the present ovarian cancer cohort. Table S4. Diseases and...

Additional file 5 of Transcriptome analysis of MYB transcription factors family and PgMYB genes involved in salt stress resistance in Panax ginseng

Mingming Liu, Ke Li, Shichao Sheng, Mingyu Wang, Panpan Hua, Yanfang Wang, Ping Chen, Kangyu Wang, Mingzhu Zhao, Yi Wang & Meiping Zhang
Additional file 5: Table S5. Weight correlation network analysis concatenation relationships and value of PgMYB gene transcripts.

Modeling and Active Learning for Experiments with Quantitative-Sequence Factors

Qian Xiao, Yaping Wang, Abhyuday Mandal & Xinwei Deng
A new type of experiment that aims to determine the optimal quantities of a sequence of factors is eliciting considerable attention in medical science, bioengineering, and many other disciplines. Such studies require the simultaneous optimization of both quantities and sequence orders of several components which are called quantitative-sequence (QS) factors. Given the large and semi-discrete solution spaces in such experiments, efficiently identifying optimal or near-optimal solutions by using a small number of experimental trials is...

Additional file 5 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Shiyu Zhang, Yinxiao Mi, Tingting Ye, Xiaoyan Lu, Li Liu, Jing Qian & Xiaohui Fan
Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups.

Additional file 6 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Shiyu Zhang, Yinxiao Mi, Tingting Ye, Xiaoyan Lu, Li Liu, Jing Qian & Xiaohui Fan
Additional file 6: Table S3. Co-regulated DEGs among the three-treatment group and Model group.

Maximum One-Factor-At-A-Time Designs for Screening in Computer Experiments

Qian Xiao, V. Roshan Joseph & Douglas M. Ray
Identifying important factors from a large number of potentially important factors of a highly nonlinear and computationally expensive black box model is a difficult problem. Morris screening and Sobol’ design are two commonly used model-free methods for doing this. In this article, we establish a connection between these two seemingly different methods in terms of their underlying experimental design structure and further exploit this connection to develop an improved design for screening called Maximum One-Factor-At-A-Time...

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rongwang wang, yaqiw wang, suiyu zhang, guiping qian, Yizheng Chen, Rong Li, xiaoyu ma & xiaodiao chen
Semantic segmentation is a hot area in computer vision (CV) research. The integration of computer vision and the film and television industry has put forward higher requirements for media data. At present, the analysis of film clips integrating high dynamics and continuous frames is one of the hot spots of video semantic segmentation. High-precision, high-volume data is the basis for proposing and improving deep learning models. However, the content labels of existing datasets are disorderly,...

Additional file 1 of Expanding known viral diversity in plants: virome of 161 species alongside an ancient canal

Shixing Yang, Qingqing Mao, Yan Wang, Jingxian He, Jie Yang, Xu Chen, Yuqing Xiao, Yumin He, Min Zhao, Juan Lu, Zijun Yang, Ziyuan Dai, Qi Liu, Yuxin Yao, Xiang Lu, Hong Li, Rui Zhou, Jian Zeng, Wang Li, Chenglin Zhou, Xiaochun Wang, Quan Shen, Hui Xu, Xutao Deng, Eric Delwart … & Wen Zhang
Additional file 1. Table S1: Plant species and library information.

Excitatory and inhibitory D-serine binding to the NMDA receptor (glycans-10dser-10glu)

Remy Yovanno & Albert Lau
N-linked mannose-5 glycans, 10 D-serine and 10 glutamate ligands
We studied the binding of D-serine to the GluN1/GluN2A NMDA receptor ligand-binding domain and found that D-serine binds to both GluN1 and GluN2A subunits, acting as an agonist for GluN1 and a competitive inhibitor at high concentrations for GluN2A.

Additional file 12 of Evolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatment

Jiapeng Yang, Caijun Xiong, Siyuan Li, Cheng Zhou, Lingli Li, Qingyun Xue, Wei Liu, Zhitao Niu & Xiaoyu Ding
Additional file 12.

Additional file 5 of Evolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatment

Jiapeng Yang, Caijun Xiong, Siyuan Li, Cheng Zhou, Lingli Li, Qingyun Xue, Wei Liu, Zhitao Niu & Xiaoyu Ding
Additional file 5.

Additional file 3 of Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood–brain barrier microvessels

Raleigh M. Linville, Matthew B. Sklar, Gabrielle N. Grifno, Renée F. Nerenberg, Justin Zhou, Robert Ye, Jackson G. DeStefano, Zhaobin Guo, Ria Jha, John J. Jamieson, Nan Zhao & Peter C. Searson
Additional file 3. Summary of tight junction dynamics data.

Additional file 6 of Evolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatment

Jiapeng Yang, Caijun Xiong, Siyuan Li, Cheng Zhou, Lingli Li, Qingyun Xue, Wei Liu, Zhitao Niu & Xiaoyu Ding
Additional file 6.

Additional file 6 of Evolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatment

Jiapeng Yang, Caijun Xiong, Siyuan Li, Cheng Zhou, Lingli Li, Qingyun Xue, Wei Liu, Zhitao Niu & Xiaoyu Ding
Additional file 6.

Registration Year

  • 2022
    220

Resource Types

  • Dataset
    220

Affiliations

  • Johns Hopkins University
    220
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    123
  • Fudan University
    119
  • Capital Medical University
    102
  • Sichuan University
    98
  • Sun Yat-sen University
    91
  • Zhejiang University
    88
  • Huazhong University of Science and Technology
    88
  • Peking University
    85
  • Chinese Academy of Sciences
    82