Additional file 1: Table S1. Expression of known miRNAs identified in wheat crown tissues.

Additional file 4: Table S3. Information of wheat_miRNA2693 and wheat_miR5099.

Additional file 14: Table S7. The network among the rumen bacterial taxa and AI-2.

Additional file 3: Table S3. The rumen microbiota and the presence of quorum sensing molecules in the rumen ecosystems of species including cattle, sheep, moose, deer, and bison (as the control group).

Additional file 3: Table S3. The rumen microbiota and the presence of quorum sensing molecules in the rumen ecosystems of species including cattle, sheep, moose, deer, and bison (as the control group).

Additional file 10: Table S6. Expression of the identified AI-2 synthases and receptors in rumen metatranscriptome datasets.

Drug-resistant pathogenic Staphylococcus aureus (S. aureus) has severely threatened human health and arouses widespread concern. Sortase A (SrtA) is an essential virulence factor of S. aureus, which is responsible for the covalent anchoring of a variety of virulence-related proteins to the cell wall. SrtA has always been regarded as an ideal pharmacological target against S. aureus infections. In this research, we have determined that orientin, a natural compound isolated from various medicinal plants, can effectively...

Additional file 2: Table S1. Genotype accuracy and concordance of imputation obtained with the three pipelines on 15 individuals. Table S2. Genotype accuracy and concordance of imputation by the three pipelines with the MAF ranges. Table S3. Genotype accuracy and concordance of imputation with different sample size and depth by BaseVar + STITCH. Table S4. Variant analysis by regions and functions. Table S5. LD decay in the Angora rabbit population. Table S6. Genes located in...

Additional file 2: Table S1. The characteristics of methylation-driven lncRNAs.

It has been well-documented that posttraumatic stress symptoms cause impairments in health-related quality of life (HRQoL). Until now we have little data on how DSM-5 PTSD symptom dimensions relate to different aspects of HRQoL. Clarifying this question would be informative to improve the quality of life of PTSD patients. This study aimed to investigate the effects of dimensions of a well-supported seven-factor model of DSM-5 PTSD symptoms on physical and psychosocial HRQoL. A total of...

Additional file 1. Two independent microarrays related to T1D (GSE156035 and GSE55098) were integrated for analysis and 19579 co-expressed genes were identified in both microarrays.

Additional file 2. The genes in the module 1 were extracted and the correlation of clustered genes with modules was calculated.

Additional file 2: Table S2. Differentially expressed genes.

Background: Homologous repair deficiency (HRD) causes double-strand break repair to be impeded, which is a common driver of carcinogenesis. However, the therapeutic and prognostic potential of HRD in invasive breast cancer (BRCA) has not been fully explored using comprehensive bioinformatics analysis. Materials and Methods: HRD score was defined as the unweighted sum of LOH, TAI, and LST scores and obtained from the previous study according to Theo A et al. To characterize BRCA tumor microenvironment...

Additional file 8: Table S7. Function annotation of 32 DEGs based on eight databases.

Additional file 5: Table S5. 373 interactions of miRNA-circRNA.

Additional file 1: Table S1. Sequencing information of nine samples.

Additional file 3: Table S3. DECs analysis of three comparisons.

Additional file 1: Table S1. Sequencing information of nine samples.

Zinc (Zn) is an important element in plants, but over-accumulation of Zn is harmful. The phytohormone brassinosteroids (BRs) play a key role in regulating plant growth, development, and response to stress. However, the role of BRs in watermelon (Citrullus lanatus L.) under Zn stress, one of the most important horticultural crops, remains largely unknown. In this study, we revealed that 24-epibrassinolide (EBR), a bioactive BR enhanced Zn tolerance in watermelon plants, which was related to...

Tumor-infiltrating lymphocytes (TILs) are vital elements of the tumor microenvironment (TME), and the anti-tumor activity of TILs on colorectal cancer (CRC) has been a topic of concern. However, the characteristics and prognosis of the various types of lymphocyte infiltration in CRC have not been fully explained. Our study aimed to identify distinct features and prognosis of TILs. We integrated multiple-cohort databases to illustrate the features, proportions, and prognosis of TILs on CRC. We found that...

Additional file 8: Table S5. Sequence of primers used in this study.

Objective To investigate the age-related changefor axial length (AL), Spherical equivalent (SE), prevalence of myopia and high myopiain children at 7 to 18 year-olds in Shanghai in 2014 and 2018, respectively, to compare these parameters between 2014 and 2018, and to evaluated the potential factors associated with AL. Design An observational study. Setting Jinshan Hospital of Fudan University in Shanghai. Methods One primary school, one junior high school, and one senior high school were randomly...

Additional file 3: Table S3. The genes corresponding to the 21 significant pathways.

Amyloidosis refers to a group of degenerative diseases that are characterized by the deposition of misfolded protein fibrils in various organs. Deposited amyloid may be removed by a phagocyte-dependent innate immune system; however, the precise mechanisms during disease progression remain unclear. We herein investigated the properties of macrophages that contribute to amyloid degradation and disease progression using inducible apolipoprotein A-II amyloidosis model mice. Intravenously injected AApoAII amyloid was efficiently engulfed by reticuloendothelial macrophages in the...