Additional file 3 of mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2ALiang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Additional file 3: Table S2. The changes of metabolite levels upon methionine restriction in livers of HCC mouce models.
Severe community-acquired pneumonia caused by Chlamydia psittaci genotype E/B strain circulating among geese in Lishui city, Zhejiang province, ChinaXin-Cheng Qin, Jinwei Huang, Zhangnv Yang, Xiangrong Sun, Wen Wang, Enhui Gong, Zhuo Cao, Jianfeng Lin, Yanai Qiu, Bohai Wen, Biao Kan, Jianguo Xu & Tian Qin
Between November 2021 and January 2022, four patients of community-acquired pneumonia were admitted to the hospitals in Lishui city, Zhejiang province, China. Their main clinical manifestations were fever and dry cough as well as radiographic infiltrate, but the empiric antimicrobial therapy or traditional Chinese medicine was not effective for their illness. Clinical specimens from the patients as well as environmental and poultry specimens were collected for the determination of the causative pathogen. The ompA gene...
A Retrospective Study of the Relationship Between Blood Transfusion and 30-Day Postoperative Outcomes in Patients Undergoing Isolated Off-Pump Coronary Artery Bypass GraftingLiangyuan Lu, Ji Che, Weiping Cheng, Ran Dong, Jiapeng Huang, Zhanmin Yang & Jiakai Lu
ABSTRACT Introduction: The objective of this single-center study it to retrospectively analyze the relationship between transfusion and 30-day postoperative outcomes in patients undergoing isolated off-pump coronary artery bypass grafting. Methods: Perioperative data of 2,178 patients who underwent isolated off-pump coronary artery bypass grafting from 2018 to 2019 were collected. A 1:1 propensity score matching was performed to control for potential biases between patients who received blood transfusion and those who did not. After propensity score...
Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host–pathogen interactions in the bat airway epitheliumLouisa L.Y. Chan, Akshamal M. Gamage, Chee Wah Tan, Kai Sen Tan, Jing Liu, Douglas Jie Wen Tay, Randy Jee Hiang Foo, Laurent Rénia, De Yun Wang & Lin-Fa Wang
Bats are reservoir hosts for various zoonotic viruses with pandemdic potential in humans and livestock. In vitro systems for studying bat host–pathogen interactions are of significant interest. Here, we establish protocols to generate bat airway organoids (AOs) and airway epithelial cells differentiated at the air–liquid interface (ALI-AECs) from tracheal tissues of the cave-nectar bat Eonycteris spelaea. In particular, we describe steps which enable laboratories that do not have access to live bats to perform extended...
Additional file 1 of Exploring the pharmacological mechanism of Shengjing capsule on male infertility by a network pharmacology approachMing Wang, Qi Wang, Hui Jiang, Yongqiang Du & Xiansheng Zhang
Additional file 1:
sj-xlsx-1-pdp-10.1177_10935266221132602 – Supplemental material for Calretinin Staining in Anorectal Line Biopsies Accurately Distinguished Hirschsprung Disease in a Retrospective StudySuzanna J. Logan, Hong Yin, Beverly Rogers, Nicoleta Arva, Miriam R. Conces, Sandy Cope-Yokoyama, Louis P. Dehner, Carlos Galliani, Shipra Garg, Mai He, Aliya N. Husain, Matthew Keisling, Chandra Krishnan, Elena Puscasiu, Christopher Rossi, Faiza Siddiqui, Lisa Sutton, Jefferson Terry, Ameet I. Thaker, Yuan Huang, Jie Zhang, Courtney McCracken & Heather Rytting
Supplemental material, sj-xlsx-1-pdp-10.1177_10935266221132602 for Calretinin Staining in Anorectal Line Biopsies Accurately Distinguished Hirschsprung Disease in a Retrospective Study by Suzanna J. Logan, Hong Yin, Beverly Rogers, Nicoleta Arva, Miriam R. Conces, Sandy Cope-Yokoyama, Louis P. Dehner, Carlos Galliani, Shipra Garg, Mai He, Aliya N. Husain, Matthew Keisling, Chandra Krishnan, Elena Puscasiu, Christopher Rossi, Faiza Siddiqui, Lisa Sutton, Jefferson Terry, Ameet I. Thaker, Yuan Huang, Jie Zhang, Courtney McCracken and Heather Rytting in Pediatric and Developmental...
Additional file 1 of The prognostic value of IPI in patients with primary breast lymphoma, a multicenter retrospective studyKexin Feng, Shuangtao Zhao, Qingyao Shang, Guangdong Qiao, Jiaxiang Liu, Chenxuan Yang, Ya Wei, Yalun Li, Fei Ren, Lixue Xuan, Xiang Wang & Xin Wang
Additional file 1: Table S1.Clinical data of each patients.
Gallbladder cancer (GBC) is the common malignancy of the bile tract system with extremely poor clinical outcomes, owing to its metastatic property and intrinsic resistance to the first-line drugs. Although it is well-established that cholesterol abnormity contributes to gallstone formation, a leading risk factor for GBC, the link of cholesterol homeostasis with GBC has not been investigated. The present study systematically examined the genes implicated in cholesterol homeostasis, and revealed altered gene expressions of de...
Additional file 1 of CSP I-plus modified rEndostatin inhibits hepatocellular carcinoma metastasis via down-regulation of VEGFA and integrinβ1Xueqin Chen, Yan Wang, Hancong Liu, Jingjing Zhang, Jie Wang, Xiaobao Jin & Yan Ma
Additional file 1: Supplementary Figures. The full-length blots of WB in Fig. 5B. Whole-cell extracts were resolved on 10% SDS-PAGE by bio-rad Mini-PROTEAN with 10 sample Wells (1Marker, 2space, 3Blank group, 4CSP I-plus group, 5Endostar group, 6rES-CSP group, 7rES-CSP+ heparin group, 8DDP group, 9space, 10Marker), and then electrotransferred onto a polyvinylidene difluoride (PVDF) membrane (Millipore). The membranes were then probed with respective primary antibodies against VEGFA, MMP2, integrinβ1, and E-cadherin procured from Abcam, β-actin from...
Additional file 4 of The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cellsQi Wang, Yongqiang Qi, Fei Xiong, Da Wang, Bing Wang & Yongjun Chen
Additional file 4: Table S1. Detailed information of the microarray used in this study.
Additional file 2 of The landscape of hervRNAs transcribed from human endogenous retroviruses across human body sitesJianqi She, Minghao Du, Zhanzhan Xu, Yueqi Jin, Yu Li, Daoning Zhang, Changyu Tao, Jian Chen, Jiadong Wang & Ence Yang
Additional file 2: Table S1-S15. Supplementary tables.
Additional file 5 of Detection of cytomegalovirus (CMV) by digital PCR in stool samples for the non-invasive diagnosis of CMV gastroenteritisJia Gu, Hongyan Ji, Tongyuan Liu, Caixia Chen, Siye Zhao, Yang Cao, Na Wang, Min Xiao, Liting Chen & Haodong Cai
Additional file 5. The details of assay validation and data analysis about figures in this study.
Data involved in this article from A game theoretical model for the stimulation of public cooperation in environmental collaborative governanceYinhai Fang, Matjaž Perc & Hui Zhang
This file provides the data for figures in this paper, as well as the code that generates the data.
Additional file 4 of Detection of cytomegalovirus (CMV) by digital PCR in stool samples for the non-invasive diagnosis of CMV gastroenteritisJia Gu, Hongyan Ji, Tongyuan Liu, Caixia Chen, Siye Zhao, Yang Cao, Na Wang, Min Xiao, Liting Chen & Haodong Cai
Additional file 4. The details of the dPCR platform and the reaction system.
METTL3-mediated long non-coding RNA MIR99AHG methylation targets miR-4660 to promote bone marrow mesenchymal stem cell osteogenic differentiationLintao Li, Beiyue Wang, Xing Zhou, Hao Ding, Chang Sun, Yicun Wang, Fan Zhang & Jianning Zhao
Whether long non-coding RNA Mir-99a-Let-7c Cluster Host Gene (LncRNA MIR99AHG) is involved in osteoporosis (OP) remains vague, so we hereby center on its implication. Old C57BL/6J mice were injected with the silencing lentivirus of MIR99AHG and subjected to microCT analysis and immunohistochemistry on osteogenic cells. The osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) with or without transfection was determined by alkaline phosphatase (ALP) and Alizarin Red S staining. Total N(6)-methyladenosine (m6A) on the...
Additional file 10 of Evolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatmentJiapeng Yang, Caijun Xiong, Siyuan Li, Cheng Zhou, Lingli Li, Qingyun Xue, Wei Liu, Zhitao Niu & Xiaoyu Ding
Additional file 10.
Additional file 1 of Clinical application of artificial neural network (ANN) modeling to predict BRCA1/2 germline deleterious variants in Chinese bilateral primary breast cancer patientsYan Li, Lili Chen, Jinxing Lv, Xiaobin Chen, Bangwei Zeng, Minyan Chen, Wenhui Guo, Yuxiang Lin, Liuwen Yu, Jialin Hou, Jing Li, Peng Zhou, Wenzhe Zhang, Shengmei Li, Xuan Jin, Weifeng Cai, Kun Zhang, Yeyuan Huang, Chuan Wang & Fangmeng Fu
Supplementary Material 1
Additional file 4 of Transcriptome and Metabolome Analyses Reveals the Pathway and Metabolites of Grain Quality Under Phytochrome B in Rice (Oryza sativa L.)Fei Li, Ye Liu, Xiaohua Zhang, Lingzhi Liu, Yun Yan, Xin Ji, Fanshu Kong, Yafan Zhao, Junzhou Li, Ting Peng, Hongzheng Sun, Yanxiu Du & Quanzhi Zhao
Additional file 4. Table S4. Network statistics of differential metabolites and related genes.
Additional file 5 of Exogenous ABA and IAA modulate physiological and hormonal adaptation strategies in Cleistocalyx operculatus and Syzygium jambos under long-term waterlogging conditionsEl-Hadji Malick Cisse, Juan Zhang, Da-Dong Li, Ling-Feng Miao, Li-Yan Yin & Fan Yang
Additional file 5.
Additional file 1 of Identification of quantitative trait loci for related traits of stalk lodging resistance using genome-wide association studies in maize (Zea mays L.)Lifen Wu, Yunxiao Zheng, Fuchao Jiao, Ming Wang, Jing Zhang, Zhongqin Zhang, Yaqun Huang, Xiaoyan Jia, Liying Zhu, Yongfeng Zhao, Jinjie Guo & Jingtang Chen
Additional file 1: Supplementary Table S1. List of genes within the 120 kb upstream and downstream extension of significant SNPs identified via GWAS. Supplementary Table S2. SNPs detected for lodging resistance-related traits using BLUP value in the association mapping panel. Supplementary Table S3. List of genes within the 120 kb upstream and downstream extension of significant SNPs identified via GWAS.
Additional file 1 of Detection of cytomegalovirus (CMV) by digital PCR in stool samples for the non-invasive diagnosis of CMV gastroenteritisJia Gu, Hongyan Ji, Tongyuan Liu, Caixia Chen, Siye Zhao, Yang Cao, Na Wang, Min Xiao, Liting Chen & Haodong Cai
Additional file 1. The dMIQE2020 checklist.
Genome assemblies and annotations of Cavendish and Gros Michel bananas
Description The Road Damage Dataset, RDD2022, is released as a part of the Crowdsensing-based Road Damage Detection Challenge (CRDDC'2022), an IEEE BigData Cup. It comprises 47,420 road images from six countries, Japan, India, the Czech Republic, Norway, the United States, and China. The images have been annotated with more than 55,000 instances of road damage. Four types of road damage, namely longitudinal cracks, transverse cracks, alligator cracks, and potholes, are captured in the dataset....
Additional file 4 of RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axisZhongbo Li, Peng Su, Yinlu Ding, Honglei Gao, Huijie Yang, Xin Li, Xiao Yang, Yan Xia, Chenmiao Zhang, Mingxi Fu, Dehai Wang, Ye Zhang, Shu Zhuo, Jian Zhu & Ting Zhuang
Additional file 3. Digital raw data.
Additional file 5 of Candidate genes screening based on phenotypic observation and transcriptome analysis for double flower of Prunus mumeHuanhuan Zhu, Yan Shi, Junwei Zhang, Manzhu Bao & Jie Zhang
Additional file 5.
Chinese Academy of Medical Sciences & Peking Union Medical College895
Shanghai Jiao Tong University762
Huazhong University of Science and Technology724
Sun Yat-sen University680
Capital Medical University668
Chinese Academy of Sciences639
Nanjing Medical University515