149 Works

Knockdown of circ_0001679 alleviates lipopolysaccharide-induced MLE-12 lung cell injury by regulating the miR-338-3p/ mitogen-activated protein kinase 1 axis

Shenggui Lu, Xinmiao Wu, Shuai Xin, Jing Zhang, Hanying Lin, Yu Miao & Yixin Li
The upregulation of circ_0001679 was reported in lipopolysaccharide (LPS)-induced lung injury mouse model, but its functional roles and mechanisms in LPS-induced lung injury remain to be investigated. In this study, we aimed to explore the potential role of circ_0001679 in septic acute lung injury. We initially established an in vitro lung cell injury model using LPS-treated MLE-12 cells. siRNAs targeting circRNA_0001679 were employed to stably knock down circRNA_0001679, followed by functional assays to investigate the...

Data from: Thyroid hormone tinkering elicits integrated phenotypic changes potentially explaining rapid adaptation of color vision in cichlid fish

Nidal Karagic, Andreas Härer, Axel Meyer & Julian Torres-Dowdall
Vision is critical for most vertebrates, including fish. One challenge that aquatic habitats pose is the high variability in spectral properties depending on depth, turbidity and composition of the water body. By altering opsin gene expression and chromophore usage, cichlid fish modulate visual sensitivities to maximize sensory input from the available light in their respective habitat. Thyroid hormone (TH) has been proposed to play a role in governing adaptive diversification in visual sensitivity in Nicaraguan...

COVID-19 survey in Baja California, Mexico, in February of 2021

Oscar E Zazueta, Richard S Garfein, J. Oggun Cano-Torres, César A Méndez-Lizárraga, Timothy C Rodwell, Raquel Muñiz-Salazar, Diego F Ovalle-Marroquín, Neiba G Yee, Idanya Rubí Serafín-Higuera, Susana González-Reyes, Jesus Rene Machado-Contreras, Lucy E Horton, Steffanie A Strathdee, Ruth Rodríguez, Linda Hill & Ietza Bojórquez-Chapela
Baja California is a State located in the north-western region of Mexico, which borders with the United States. This area is of particular importance in terms of epidemiological surveillance, given that the busiest port of entry to the U.S. is located in the Tijuana-San Diego region, which is also one of the busiest ports of entry in the world. During the first year of the COVID-19 pandemic, Baja California had the second mortality rate in...

DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m6A modification and translation for cytoprotective autophagy in cervical cancer

Miaohua Zhu, Weiwei Shen, Qiming Wang, Xiaoming Zhou, Jiaying Wang, Tingting Wang & Jing Zhang
Cervical cancer (CC) is one of the most prevalent malignancies among females. Cytoprotective autophagy could confer cancer cell tolerance to hypoxic stress, promoting cell survival and adaptation. Aspartyl-tRNA synthetase 1 antisense 1 (DARS-AS1) is an oncogenic long non-coding RNA (lncRNA) in various cancers, but how DARS-AS1 regulates cytoprotective autophagy in hypoxic environment in CC remains unclear. Chromatin immunoprecipitation (ChIP) and luciferase reporter assays were conducted to explore the interaction between hypoxia-inducible factor 1 subunit alpha...

Table S10.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S1.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S7.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S3.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Table S11.xlsx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Additional file 10 of TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway

Rong Li, Jing Zhang, Qiong Wang, Meng Cheng & Bin Lin
Additional file 10: Table S1. The sequences for all primers and siRNA.

Data: Canonical host-pathogen tradeoffs subverted by mutations with dual benefits

Justin Meyer
Host-parasite coevolution is expected to drive the evolution of genetic diversity because the traits used in arms races, namely host range and parasite resistance, are hypothesized to trade off with traits used in resource competition. We therefore tested data for several tradeoffs among 93 isolates of bacteriophage and 51 Escherichia coli genotypes that coevolved during a laboratory experiment. Surprisingly, we found multiple tradeups (positive trait correlations) but little evidence of several canonical tradeoffs. For example,...

Assessing pre-pandemic carbon footprint of diet transitions in UK nations and regions

Mustafa Ali, S. C. Lenny Koh, Lingxuan Liu, Jing Zhang, William Roberts, Dawn Robins & Dave Cooper
Food supply chains hold significant embodied carbon emissions that need to be mitigated and neutralized. This study aimed to explore the historical Greenhouse Gas (GHG) emissions associated with household food consumption at a local scale i.e. across the eight English regions and the four nations that comprise the United Kingdom (UK). UK EatWell guidelines were used to explore the potential change in emissions and food costs in a scenario of transitions to healthier diets across...

Daily totals of odontocete acoustic presence at western North Atlantic acoustic monitoring sites

Rebecca E. Cohen, Kaitlin E. Frasier, Simone Baumann-Pickering, Sean Wiggins, Macey A. Rafter, Lauren M. Baggett & John A. Hildebrand
A combination of machine learning and expert analyst review was used to detect odontocete echolocation clicks, identify dominant click types, and classify clicks in 32 years of acoustic data collected at 11 autonomous monitoring sites in the western North Atlantic between 2016 and 2019. Previously-described click types for eight known odontocete species or genera were identified in this data set: Blainville’s beaked whales (Mesoplodon densirostris), Cuvier’s beaked whales (Ziphius cavirostris), Gervais’ beaked whales (Mesoplodon europaeus),...

Intermittent preventive treatment with Sulfadoxine pyrimethamine for malaria: a global overview and challenges affecting optimal drug uptake in pregnant women

Rodrigue Roman Dongang Nana, Joseph Hawadak, Loick Pradel Kojom Foko, Amit Kumar, Shewta Chaudhry, Aditi Arya & Vineeta Singh
Malaria in Pregnancy (MiP) leading to morbidity and mortality is a major public health problem that poses significant risk to pregnant women and their fetus. To cope with this alarming situation, administration of Sulfadoxine-pyrimethamine (SP) drugs to pregnant women as an intermittent preventive treatment (IPT) from 16 weeks of gestation is recommended by the World Health Organization (WHO) guidelines. We conducted a comprehensive search of published articles related to MiP in last 10 years with...

Additional file 2 of Multi-technique analysis of pigments on sandstone sculptures: Renaissance re-painting of a Roman relief

Louisa Campbell & Margaret Smith
Additional file 2: Appendix SI. pXRF results.

sj-xlsx-1-npx-10.1177_1934578X221131126 - Supplemental material for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology

Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang & Xiao Liu
Supplemental material, sj-xlsx-1-npx-10.1177_1934578X221131126 for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology by Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang and Xiao Liu in Natural Product Communications

sj-xlsx-3-npx-10.1177_1934578X221131126 - Supplemental material for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology

Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang & Xiao Liu
Supplemental material, sj-xlsx-3-npx-10.1177_1934578X221131126 for Quercetin and Luteolin may be the New Effective Drugs for Radiation Pneumonitis: Based on a Systems Pharmacology by Mengmei Zhang, Guangcai Li, Huaqing Hu, Mu Yi, Yang Li, Jihang Luo, Yan Tang, Guangmin Xu, Ze Yang and Xiao Liu in Natural Product Communications

Improving winter wheat yield estimation under complex irrigation conditions through coupling APSIM crop growth model and the machine learning approach

Quandi Niu, Jianxi Huang, Xuecao Li, Hai Huang, Haixiang Guan, Wei Wang, Wei Su, Li Li, Shuangxi Miao & Dongqin Yin
The annual dynamics of winter wheat yield in Henan, China from 2018 to 2021 are provided, with the resolution of 20m and GeoTiff format.

Prey naiveté alters the balance of consumptive and non-consumptive predator effects and shapes trophic cascades in freshwater plankton

Henry Baker, Stephanie Li, Stefan Samu, Natalie Jones, Celia Symons & Jonathan Shurin
Predators drive trophic cascades by reducing prey biomass and altering prey traits, selecting for prey that exhibit constitutive and induced anti-predator defenses that decrease susceptibility to consumption. These defense traits are often costly, generating a tradeoff between consumptive (CEs) and non-consumptive predator effects (NCEs). The ecological and evolutionary experience that prey share with a given predator may determine their position along this tradeoff curve, affecting the nature and strength of top-down control of ecosystems. Conceptual...

Additional file 1 of The distribution of bioactive gibberellins along peach annual shoots is closely associated with PpGA20ox and PpGA2ox expression profiles

Mengmeng Zhang, Yangtao Ma, Xianbo Zheng, Bin Tan, Xia Ye, Wei Wang, Langlang Zhang, Jidong Li, Zhiqian Li, Jun Cheng & Jiancan Feng
Additional file 1: Figure S1. Verification of PpKO gene structure using the alignment results of reads obtained from the transcriptome of peach flowers, stems, fruits and pits. Figure S2. Sequence alignment of GA20ox from Arabidopsis and peach. The LPWKET motif are underlined. Figure S3. The phylogenetic trees of CPS (A), KS (B), KO (C), KAO (D) and GA3ox (E). The amino acid sequences were downloaded from Phytozome database and the Gene ID are listed after...

Additional file 5 of Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis

Liming Zhang, Yuxiang Wang, Li Qiu & Jian Wu
Additional file 5. The direct transcripts of the executed search strategies about HF and psoriasis.

Additional file 1 of A two-step process for in silico screening to assess the performance of qRTPCR kits against variant strains of SARS-CoV-2

Swati Gupta, Amit Kumar, Nivedita Gupta, Deepak R. Bharti, Neeraj Aggarwal & Vasanthapuram Ravi
Additional file 1.

Supplemental data for: Longitudinal, multi-platform metagenomics yields a high-quality genomic catalog and guides an in vitro model for cheese communities

Christina C. Saak, Emily C. Pierce, Cong B. Dinh, Daniel Portik, Richard Hall, Meredith Ashby & Rachel J. Dutton
Microbiomes are intricately intertwined with human health, geochemical cycles, and food production. While many microbiomes of interest are highly complex and experimentally intractable, cheese rind microbiomes have proven powerful model systems for the study of microbial interactions. To provide a more comprehensive view of the genomic potential and temporal dynamics of cheese rind communities, we combine longitudinal, multi-platform metagenomics of three ripening washed-rind cheeses with whole genome sequencing of community isolates. Sequencing-based approaches revealed a...

Additional file 1 of A two-step process for in silico screening to assess the performance of qRTPCR kits against variant strains of SARS-CoV-2

Swati Gupta, Amit Kumar, Nivedita Gupta, Deepak R. Bharti, Neeraj Aggarwal & Vasanthapuram Ravi
Additional file 1.

Adipose Tissue from Subjects with Type 2 Diabetes Exhibits Impaired Capillary Formation in Response to GROα: Involvement of MMPs-2 and -9

Yifat Amir Levy, Theodore P Ciaraldi, Sunder R. Mudaliar, Susan A. Phillips & Robert R. Henry
Type 2 Diabetes (T2D) is associated with impaired vascularization of adipose tissue (AT) and skeletal muscle. IL8, GROα and IL15 are pro-angiogenic myokines; T2D myotubes secrete high levels of all 3 factors. We aimed to explore the direct impact of these myokines on AT vascularization. Subcutaneous AT explants from subjects with T2D (n=15) and without diabetes (non-diabetic, ND, n=14) subjects were treated with rIL8, rGROα and rIL15 in concentrations equal to those in conditioned media...

Registration Year

  • 2022
    149

Resource Types

  • Dataset
    149

Affiliations

  • University of California, San Diego
    149
  • Zhejiang University
    80
  • Sun Yat-sen University
    75
  • Fudan University
    74
  • Lanzhou University
    74
  • University of Chinese Academy of Sciences
    70
  • Air Force Medical University
    68
  • Ministry of Agriculture and Rural Affairs
    68
  • Chinese Academy of Sciences
    63
  • Sixth Affiliated Hospital of Sun Yat-sen University
    62