60 Works

Additional file 1 of Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits

Babatunde S. Olasege, Laercio R. Porto-Neto, Muhammad S. Tahir, Gabriela C. Gouveia, Angela Cánovas, Ben J. Hayes & Marina R. S. Fortes
Additional file 1. The number of windows, chromosome number, chromosome coordinates, and correlation estimates of each window for the two trait pairs in Brahman and Tropical Composite population (Table S1-S2).

Differentials in death count records by databases in Brazil in 2010

Victor Hugo Dias Diógenes, Elzo Pereira Pinto Júnior, Marcos Roberto Gonzaga, Bernardo Lanza Queiroz, Everton E. C. Lima, Lilia Carolina C. da Costa, Aline S. Rocha, Andrêa J. F. Ferreira, Camila S. S. Teixeira, Flávia Jôse O. Alves, Leila Rameh, Renzo Flores-Ortiz, Alastair Leyland, Ruth Dundas, Maurício L. Barreto & Maria Yury Travassos Ichihara
ABSTRACT OBJECTIVE To compare the death counts from three sources of information on mortality available in Brazil in 2010, the Mortality Information System (SIM - Sistema de Informações sobre Mortalidade ), Civil Registration Statistic System (RC - Sistema de Estatísticas de Resgistro Civil ), and the 2010 Demographic Census at various geographical levels, and to confirm the association between municipal socioeconomic characteristics and the source which showed the highest death count. METHODS This is a...

Deep vicariance and frequent transoceanic dispersal shape the evolutionary history of a globally distributed fern family

Weston Testo, Andre Gasper, Sonia Molino, José María Gabriel Y Galán, Alexandre Salino, Vinícius Dittrich & Emily Sessa
Premise Historical biogeography of ferns is typically expected to be dominated by long-distance dispersal, due to their minuscule spores. However, few studies have inferred the historical biogeography of a large and widely distributed group of ferns to test this hypothesis. Our aims are to determine the extent to which long-distance dispersal vs. vicariance have shaped the history of the fern family Blechnaceae, to explore ecological correlates of dispersal and diversification, and to determine whether these...

Education and other determinants of older adults’ participation in labor force in Brazil

Anderson Rocha de Jesus Fernandes & Bernardo Lanza Queiroz
Abstract The extension of working life is associated with the accumulated years of schooling of individuals and with the characteristics of the pension system (COILE, 2018; GRUBER; WISE, 1999). In Brazil, people are acquiring years of education and beginning to work later. However, the availability of retirement programs make them leave early, despite increasing longevity (QUEIROZ; FERREIRA, 2021). This paper aims to characterize the changes in the labor force participation of elderly people across time,...

Time trends of physical activity for leisure and transportation in the Brazilian adult population: results from Vigitel, 2010-2019

Alessandra de Carvalho Bastone, Bruno de Souza Moreira, Karina Simone de Souza Vasconcelos, Amanda Silva Magalhães, Débora Moraes Coelho, Juliana Ilídio da Silva, Vanessa Moraes Bezerra, Adalberto Aparecido dos Santos Lopes, Amélia Augusta de Lima Friche, Waleska Teixeira Caiaffa & Amanda Cristina de Souza Andrade
This time-series study examined a 10-year historical series of the physical activity prevalence for leisure and transportation in the Brazilian adult population. Information from 512,969 adults interviewed from the Vigitel between 2010 and 2019 was analyzed. Individuals who reported practicing at least 150 minutes/week of moderate-intensity physical activity or at least 75 minutes/week of vigorous-intensity physical activity were considered active during leisure time. Individuals who reported walking or cycling to/from work, course, or school at...

Mortality differentials in beneficiaries of the National Institute of Social Security of Brazil in 2015

Marcos Roberto Gonzaga, Everton Emanuel Campos Lima, Bernardo Lanza Queiroz, Graziela Ansiliero & Flávio Henrique Miranda de Araújo Freire
ABSTRACT This paper aims to estimate mortality and analyze its differentials by sex, age, and groups of beneficiaries of the Brazilian National Institute of Social Security (INSS) in 2015 and make comparisons with official estimates for the general population, assessing the distribution of deaths by age and of survival after 65 years old. The results reinforce the need for more studies on mortality differentials between beneficiary groups and for continuous investment to improve the quality...

Data for: Evaluating the impact of anatomical partitioning on summary topologies obtained with Bayesian phylogenetic analyses of morphological data

Daniel Casali, Felipe Freitas & Fernando Perini
Morphological data are a fundamental source of evidence to reconstruct the Tree of Life, and Bayesian phylogenetic methods are increasingly being used for this task. Bayesian phylogenetic analyses require the use of evolutionary models, which have been intensively studied in the past few years, with significant improvements to our knowledge. Notwithstanding, a systematic evaluation of the performance of partitioned models for morphological data has never been performed. Here we evaluate the influence of partitioned models,...

Data from: Unwrapping broken tails: Biological and environmental correlates of predation pressure in limbless reptiles

Mario R. Moura, Henrique C. Costa, Arthur D. Abegg, Esmeralda Alaminos, Teddy Angarita-Sierra, Weverton S. Azevedo, Hugo Cabral, Priscila Carvalho, Sonia Cechin, Nathalie Citeli, Ângelo C. M. Dourado, André F. V. Duarte, Frederico G. R. França, Eliza M. X Freire, Paulo C. A. Garcia, Rafael Mol, Ricardo Montero, Antônio Moraes-Da-Silva, Daniel C. Passos, Paulo Passos, Renata Perez, Juan M. Pleguezuelos, Pedro Prado, Ana Lúcia C. Prudente, Raul F. D. Sales … & Jhonny J. M. Guedes
Studying species interactions in nature often requires elaborate logistics and intense fieldwork. The difficulties in such task might hinder our ability to answer questions on how biotic interactions change with the environment. Fortunately, a workaround to this problem lies within scientific collections. For some animals, the inspection of preserved specimens can reveal the scars of past antagonistic encounters, such as predation attempts. A common defensive behaviour that leaves scars on animals is autotomy, the loss...

Additional file 8 of Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits

Babatunde S. Olasege, Laercio R. Porto-Neto, Muhammad S. Tahir, Gabriela C. Gouveia, Angela Cánovas, Ben J. Hayes & Marina R. S. Fortes
Additional file 8. The enriched QTLs of the driver and antagonizing regions for all trait pairs in Brahman and Tropical Composite cattle. The enriched QTLs are rank based on the adj.pval (Table S21-28).

Clinical genomics and precision medicine

Sérgio D. J. Pena & Eduardo Tarazona-Santos
Abstract Precision Medicine emerges from the genomic paradigm of health and disease. For precise molecular diagnoses of genetic diseases, we must analyze the Whole Exome (WES) or the Whole Genome (WGS). By not needing exon capture, WGS is more powerful to detect single nucleotide variants and copy number variants. In healthy individuals, we can observe monogenic highly penetrant variants, which may be causally responsible for diseases, and also susceptibility variants, associated with common polygenic diseases....

Additional file 5 of Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits

Babatunde S. Olasege, Laercio R. Porto-Neto, Muhammad S. Tahir, Gabriela C. Gouveia, Angela Cánovas, Ben J. Hayes & Marina R. S. Fortes
Additional file 5. The number of windows, chromosome number, chromosome coordinates, correlation estimates and rank value for the drivers and antagonizing regions (Bonferroni corrected p < 0.05) in Brahman (BB) and Tropical Composite population for the studied trait (Table S12-19).

Management in severe dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Sonia Maria Dozzi Brucki, Ivan Aprahamian, Wyllians Vendramini Borelli, Victor Calil da Silveira, Ceres Eloah de Lucena Ferretti, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Ricardo Nitrini, Rodrigo Rizek Schultz & Lilian Schafirovits Morillo
ABSTRACT Alzheimer’s disease (AD) and other neurodegenerative dementias have a progressive course, impairing cognition, functional capacity, and behavior. Most studies have focused on AD. Severe dementia is associated with increased age, higher morbidity-mortality, and rising costs of care. It is fundamental to recognize that severe dementia is the longest period of progression, with patients living for many years in this stage. It is the most heterogeneous phase in the process, with different abilities and life...

Diagnosis of vascular cognitive impairment: recommendations of the scientific department of cognitive neurology and aging of the Brazilian Academy of Neurology

Breno José Alencar Pires Barbosa, José Ibiapina Siqueira Neto, Gilberto Sousa Alves, Felipe Kenji Sudo, Claudia Kimie Suemoto, Fernanda Tovar-Moll, Jerusa Smid, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Eliasz Engelhardt & Márcia Lorena Fagundes Chaves
ABSTRACT Since the publication of the latest recommendations for the diagnosis and treatment of Vascular Dementia by the Brazilian Academy of Neurology in 2011, significant advances on the terminology and diagnostic criteria have been made. This manuscript is the result of a consensus among experts appointed by the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology (2020-2022). We aimed to update practical recommendations for the identification, classification, and diagnosis of...

Subjective cognitive decline, mild cognitive impairment, and dementia - syndromic approach: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Jerusa Smid, Adalberto Studart-Neto, Karolina Gouveia César-Freitas, Marcia Cristina Nascimento Dourado, Renata Kochhann, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Elisa de Paula França Resende & Francisco Assis Carvalho Vale
ABSTRACT This consensus, performed by the Brazilian Academy of Neurology (BAN) will approach practically how to evaluate patients with cognitive complaints and how to clinically and etiologically diagnose the three clinical syndromes associated with the different stages of cognitive decline: subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia. This BAN consensus discusses SCD diagnosis for the first time, updates MCI and dementia diagnoses, recommends the adequate cognitive tests and the relevant etiological work-up...

Epicardial Fat Volume Is Associated with Endothelial Dysfunction, but not with Coronary Calcification: From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Karina P. M. P. Martins, Sandhi M. Barreto, Daniel Bos, Jesiana Pedrosa, Douglas R. M. Azevedo, Larissa Fortunato Araújo, Murilo Foppa, Bruce B. Duncan, Antonio Luiz P. Ribeiro & Luisa C. C. Brant
Abstract Background The increase in epicardial fat volume (EFV) is related to coronary artery disease (CAD), independent of visceral or subcutaneous fat. The mechanism underlying this association is unclear. Coronary artery calcium (CAC) score and endothelial dysfunction are related to coronary events, but whether EFV is related to these markers needs further clarification. Objectives To evaluate the association between automatically measured EFV, cardiovascular risk factors, CAC, and endothelial function. Methods In 470 participants from the...

Diagnosis and management of Parkinson’s disease dementia and dementia with Lewy bodies: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Jacy Bezerra Parmera, Vitor Tumas, Henrique Ballalai Ferraz, Mariana Spitz, Maira Tonidandel Barbosa, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Raphael Machado Castilhos & Norberto Anízio Ferreira Frota
ABSTRACT Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) represent the second most common type of degenerative dementia in patients aged 65 years and older, leading to progressive cognitive dysfunction and impaired quality of life. This study aims to provide a consensus based on a systematic Brazilian literature review and a comprehensive international review concerning PDD and DLB. Moreover, we sought to report on and give recommendations about the best diagnostic approaches focusing...

Additional file 1 of Testing the effects of 4-week training programs based on extreme and medium-sided soccer games: a study focusing on change-of-direction, vertical jump height and locomotor profile

Piotr Makar, Gibson Praça, Adam Kawczyński, Zeki Akyildiz, Mehmet yıldız, Rodrigo Aquino & Filipe Manuel Clemente
Additional file 1. Dataset of the study.

Identification and characterization of pathogenic and multidrug-resistant bacteria in feral pigeons surrounding a veterinary hospital in Minas Gerais, Brazil

Jordana Almeida Santana, Carolina Pantuzza Ramos, Brendhal Almeida Silva, Graciela Kunrath Lima, Alexandra Tiso Comerlato, Amanda Cristina Araújo, Salene Angelini Colombo, Gustavo Canesso Bicalho & Rodrigo Otávio Silveira Silva
ABSTRACT: Pigeons are known for their capacity to harbor and spread several zoonotic agents. Studies have suggested that pigeons are also relevant disseminators of multidrug-resistant strains. In this study, pigeons surrounding a veterinary hospital were sampled and tested for the presence of pathogenic Escherichia coli, Salmonella spp., Staphylococcus spp., and Clostridioides (Clostridium) difficile. E. coli isolates from 19 (40.4%) pigeons tested positive for the E. coli heat-stable enterotoxin 1 (EAST1)-encoding gene. The intimin-encoding gene (eae)...

Dung beetles maintain phylogenetic divergence but functional convergence across a highly fragmented tropical landscape

Jose D. Rivera, Alejandro Espinosa De Los Monteros, Pedro G. Da Silva & Mario E. Favila
Understanding how human-modified landscapes affect the phylogenetic composition and assembly mechanisms of biological communities is critical for effectively managing and restoring tropical ecosystems. We evaluated how forest coverage loss, fragmentation, and landscape heterogeneity affect the phylogenetic diversity of dung beetles and their assembly mechanisms in Los Tuxtlas Biosphere Reserve, a protected but highly fragmented tropical landscape. We calculated Faith's phylogenetic diversity, mean pairwise phylogenetic distance, and mean nearest taxon distance for 5,388 individuals in 36...

Relationship of woody species composition with edaphic characteristics in threatened riparian Atlantic Forest remnants in the upper Rio Doce basin, Brazil

Yule Nunes, João Carlos Figueiredo, Marly Antonielle Ávila, Camila Souza, José Gustavo Neves, Glaúcia Tolentino, Yumi Oki, Islaine Francielly Azevedo, Daniel Negreiros, João Herbert Viana, Rubens Santos, Rúbia Fonseca & Geraldo Wilson Fernandes
Studies on the composition, richness, and diversity of plant species in tropical communities are essential for understanding relevant ecological processes and for developing appropriate conservation policies. Considering that areas subject to direct impacts due to dam breach may in the long-term present changes in species composition and in soil parameters, we evaluated the composition of the flora, described the current vegetation profile, and evaluated whether differences in species composition was influenced by soil variables of...

Diagnosis of frontotemporal dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Leonardo Cruz de Souza, Mirna Lie Hosogi, Thais Helena Machado, Maria Teresa Carthery-Goulart, Mônica Sanches Yassuda, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Valéria Santoro Bahia & Leonel Tadao Takada
ABSTRACT “Frontotemporal dementia” (FTD) is a clinical syndrome characterized by the focal involvement of the frontal and/or temporal lobes. FTD has three clinical phenotypes: the behavioral variant and two linguistic subtypes, namely, non-fluent/agrammatic primary progressive aphasia (PPA-NF/A) and semantic PPA (PPA-S). FTD is the second most common cause of dementia in individuals under the age of 65 years. This article presents recommendations for the diagnosis of FTD in the Brazilian scenario, considering the three levels...

COVID-19 outbreaks among crew members in non-cruise vessels anchoring in Salvador, Brazil, 2021

Cristiane Wanderley Cardoso, Mirela Maisa da Silva Souza, Ana Claudia Venegeroles de Sá Teles, Hernan Dario Argibay, Olivete Borba dos Reis, Felicidade Mota Pereira, Marta Giovanetti, Tereza Magalhaes & Guilherme Sousa Ribeiro
BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected the maritime sector due to virus transmission onboard and traffic restrictions. However, reports of SARS-CoV-2 transmission on board have been mostly restricted to those occurring on cruise ships. OBJECTIVES To report COVID-19 outbreaks in eight non-cruise vessels and discuss measures to prevent and control the onboard transmission of SARS-CoV-2. METHODS We investigated outbreaks of COVID-19 on...

Clinical genomics and precision medicine

Sérgio D. J. Pena & Eduardo Tarazona-Santos
Abstract Precision Medicine emerges from the genomic paradigm of health and disease. For precise molecular diagnoses of genetic diseases, we must analyze the Whole Exome (WES) or the Whole Genome (WGS). By not needing exon capture, WGS is more powerful to detect single nucleotide variants and copy number variants. In healthy individuals, we can observe monogenic highly penetrant variants, which may be causally responsible for diseases, and also susceptibility variants, associated with common polygenic diseases....

Diagnosis and management of Parkinson’s disease dementia and dementia with Lewy bodies: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Jacy Bezerra Parmera, Vitor Tumas, Henrique Ballalai Ferraz, Mariana Spitz, Maira Tonidandel Barbosa, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Raphael Machado Castilhos & Norberto Anízio Ferreira Frota
ABSTRACT Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) represent the second most common type of degenerative dementia in patients aged 65 years and older, leading to progressive cognitive dysfunction and impaired quality of life. This study aims to provide a consensus based on a systematic Brazilian literature review and a comprehensive international review concerning PDD and DLB. Moreover, we sought to report on and give recommendations about the best diagnostic approaches focusing...

Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Paulo Caramelli, Valeska Marinho, Jerson Laks, Marcus Vinicius Della Coletta, Florindo Stella, Einstein Francisco Camargos, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Helen Bedinoto Durgante & Paulo Henrique Ferreira Bertolucci
ABSTRACT There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life. Current treatment approaches are based on etiology, symptom profile and stage of dementia. This manuscript presents recommendations on pharmacological and non-pharmacological treatments of dementia due to Alzheimer’s disease, vascular cognitive impairment, frontotemporal dementia, Parkinson’s disease dementia, and dementia with Lewy bodies.

Registration Year

  • 2022
    60

Resource Types

  • Dataset
    60

Affiliations

  • Universidade Federal de Minas Gerais
    60
  • Universidade de São Paulo
    14
  • University of Queensland
    10
  • University of Guelph
    10
  • Agriculture and Food
    10
  • Commonwealth Scientific and Industrial Research Organisation
    10
  • Erasmus MC
    4
  • Federal University of Bahia
    4
  • Oswaldo Cruz Foundation
    4
  • University of Glasgow
    2