2 Works

Data from: In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

Fernanda Bajanca, Vinicio Gonzalez-Perez, Sean J. Gillespie, Cyriaque Beley, Luis Garcia, Eric Theveneau, Richard P. Sear & Simon M. Hughes
Dystrophin forms an essential link between sarcolemma and cytoskeleton, perturbation of which causes muscular dystrophy. We analysed Dystrophin binding dynamics in vivo for the first time. Within maturing fibres of host zebrafish embryos, our analysis reveals a pool of diffusible Dystrophin and complexes bound at the fibre membrane. Combining modelling, an improved FRAP methodology and direct semi-quantitative analysis of bleaching suggests the existence of two membrane-bound Dystrophin populations with widely differing bound lifetimes: a stable,...

Reduced sexual size dimorphism in a pipefish population where males do not prefer larger females

Nuno Monteiro, Mário Cunha, Nídia Macedo, Jonathan Wilson, Gunilla Rosenqvist & Anders Berglund
Within a species’ distribution, populations are often exposed to diverse environments and may thus experience different sources of both natural and sexual selection. These differences are likely to impact the balance between costs and benefits to individuals seeking reproduction, thus entailing evolutionary repercussions. Here, we look into an unusual population (Baltic Sea) of the broadnosed pipefish, Syngnathus typhle, where males do not seem to select females based on size and hypothesise that this pattern may...

Registration Year

  • 2021
    1
  • 2015
    1

Resource Types

  • Dataset
    2

Affiliations

  • Centre de Biologie du Développement
    2
  • University of Surrey
    1
  • King's College London
    1
  • Inserm
    1
  • University of Porto
    1
  • Lusíada University of Porto
    1
  • Scientific Centre of Monaco
    1
  • Department of Earth Sciences
    1