169 Works

UPITT IVIS High-Temperature FTIR Data (Microfurnace)

James Thompson, Daniel Williams, Rachel Jennifer Lee & Michael Sean Ramsey
This data is related to the following manuscript: Quantitative thermal emission spectroscopy at high-temperatures: A laboratory approach for measurement and calibration. A new microfurnace was developed to heat mineral and rock samples to temperatures between 473 and 1573 K. It was designed to integrate with an existing Nicolet Nexus 670 FTIR spectrometer (with a a liquid nitrogen-cooled mercury cadmium telluride (MCT-B) detector)allowing quantitative emission spectra of samples over the 4000 – 500 cm-1 (2.5 –...

Data associated with publication: \"Hard-material Adhesion: Which Scales of Roughness Matter?\" by L.A. Thimons, A. Gujrati, A. Sanner, L. Pastewka, T.D.B. Jacobs, published in Experimental Mechanics, 2021

Luke Thimons, Abhijeet Gujrati, Antoine Sanner, Lars Pastewka & Tevis Jacobs
Data associated with publication: "Hard-material Adhesion: Which Scales of Roughness Matter?" by L.A. Thimons, A. Gujrati, A. Sanner, L. Pastewka, T.D.B. Jacobs, published in Experimental Mechanics, 2021

Quarry 2 Floor Tile

Ruikang Ding, Abhijeet Gujrati, Matthew M. Pendolino, Kurt E. Beschorner & Tevis D. B. Jacobs
These are surface profiles of quarry 2 rough flooring. The quarry 1 (0T01881P, Daltile, Dallas, TX, USA) and quarry 2 (01 010 SM 1, Summitville, OH, USA) were commercial tiles, where the full composition was a trade secret, but they were known to include 15-25 wt% quartz, and quarry 2 also included abrasive grits on the surface, presumably to improve slip resistance. There are 30 profiles generated from image analysis and measured by SEM. 10...

Polished Ultrananocrystalline Diamond

Abhijeet Gujrati, Subarna R. Khanal, Lars Pastewka & Tevis D. B. Jacobs
Polished UNCD surface topography measured using TEM, AFM, and Stylus Profilometry

Data from: Discovery of metabolic biomarkers for Duchenne Muscular Dystrophy within a natural history study

Simina M. Boca, Maki Nishida, Michael Harris, Shruti Rao, Amrita K. Cheema, Kirandeep Gill, Haeri Seol, Lauren P. Morgenroth, Erik Henricson, Craig McDonald, Jean K. Mah, Paula R. Clemens, Eric P. Hoffman, Yetrib Hathout & Subha Madhavan
Serum metabolite profiling in Duchenne muscular dystrophy (DMD) may enable discovery of valuable molecular markers for disease progression and treatment response. Serum samples from 51 DMD patients from a natural history study and 22 age-matched healthy volunteers were profiled using liquid chromatography coupled to mass spectrometry (LC-MS) for discovery of novel circulating serum metabolites associated with DMD. Fourteen metabolites were found significantly altered (1% false discovery rate) in their levels between DMD patients and healthy...

Data from: Fat, fibre and cancer risk in African Americans and rural Africans

Stephen J. D. O’Keefe, Jia V. Li, Leo Lahti, Junhai Ou, Franck Carbonero, Mohammed Khaled, Joram M. Posma, James Kinross, Elaine Wahl, Elizabeth Ruder, Kishore Vipperla, Vasudevan Naidoo, Lungile Mtshali, Sebastian Tims, Philippe G. B. Puylaert, James DeLany, Alyssa Krasinskas, Ann C. Benefiel, Hatem O. Kaseb, Keith Newton, Jeremy K. Nicholson, Willem M. De Vos, H. Rex Gaskins & Erwin G. Zoetendal
Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (<5:100,000). The higher rates are associated with higher animal protein and fat, and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain fatty acid quantities and higher mucosal proliferative biomarkers of cancer risk in otherwise healthy middle-aged volunteers. Here we investigate further the role of fat and fibre in this association. We performed 2-week food exchanges in...

Data from: The expression of established cognitive brain states stabilizes with working memory development

David Florentino Montez, Finnegan J. Calabro & Beatriz Luna
We present results from a longitudinal study conducted over 10 years in a sample of 126 8-33 year olds demonstrating that adolescent development of working memory is supported by decreased variability in the amplitude of expression of whole brain states of task-related activity. fMRI analyses reveal that putative gain signals affecting maintenance and retrieval aspects of working memory processing stabilize during adolescence, while those affecting sensorimotor processes do not. We show that trial-to-trial variability in...

Neural activity during a simple reaching task in macaques is counter to gating and rebound in basal ganglia-thalamic communication

Bettina Schwab, Daisuke Kase, Andrew Zimnik, Robert Rosenbaum, Marcello Codianni, Jonathan Rubin & Robert Turner
Task-related activity in the ventral thalamus, a major target of basal ganglia output, is often assumed to be permitted or triggered by changes in basal ganglia activity through gating- or rebound-like mechanisms. To test those hypotheses, we sampled single-unit activity from connected basal ganglia output and thalamic nuclei (globus pallidus-internus, GPi, and ventrolateral-anterior nucleus, VLa) in monkeys performing a reaching task. Rate increases were the most common peri-movement change in both nuclei. Moreover, peri-movement changes...

Mouse substantia nigra responses to optogenetic stimulation of projections from striatum and globus pallidus

Ryan Phillips, Ian Rosner, Aryn Gittis & Jonathan Rubin
As a rodent basal ganglia (BG) output nucleus, the substantia nigra pars reticulata (SNr) is well positioned to impact behavior. SNr neurons receive GABAergic inputs from the striatum (direct pathway) and globus pallidus (GPe, indirect pathway). Dominant theories of action selection rely on these pathways' inhibitory actions. Yet, experimental results on SNr responses to these inputs are limited and include excitatory effects. Our study combines experimental and computational work to characterize, explain, and make predictions...

Data from: Novel sources of (co)variation in nestling begging behavior and hunger at different biological levels of analysis

Daniel Wetzel, Ariane Mutzel, Jonathan Wright & Niels Dingemanse
Biological hypotheses predicting patterns of offspring begging typically concern the covariance with hunger and/or development at specific hierarchical levels. For example, hunger drives within-individual patterns of begging, but begging also drives food intake among individuals within broods, and begging and food intake can covary positively or negatively among genotypes or broods. Testing biological phenomena that occur at multiple levels therefore requires the partitioning of covariance between traits of interest to ensure that each level-specific relationship...

Orthostatic hypotension, dizziness, neurology outcomes, and death in older adults, supplement methods & tables, STROND checklist

Stephen Juraschek, , Oscar L. Lopez, John S Gottdiener, Lewis A Lipsitz, Lewis H. Kuller & Kenneth J Mukamal
Objective To test the hypothesis that orthostatic hypotension (OH) might cause cerebral hypoperfusion and injury, we examined the longitudinal relationship between orthostatic hypotension (OH) or orthostatic symptoms and incident neurologic outcomes in a community population of older adults. Methods Cardiovascular Health Study (CHS) participants (≥65yrs) without dementia or stroke had blood pressure (BP) measured after lying 20-minutes and after standing 3-minutes. Participants reported dizziness immediately upon standing and any dizziness in the past 2wks. OH...

Data from: Nonnative old-field species inhabit early-season phenological niches and exhibit unique sensitivity to climate

Rachel Reeb, Isabel Acevedo, Mason Heberling & Sara Kuebbing
Native and nonnative plant species can exhibit differences in the timing of their reproductive phenology as well as their phenological sensitivity to climate. These contrasts may influence species’ interactions and the invasion potential of nonnative species; however, a limited number of phenology studies expressly consider phenological mismatches among native and nonnative species over broad spatial or temporal scales. To fill this knowledge gap, we used two complementary approaches: first, we quantified the flowering phenology of...

Data associated with \"Floral pigmentation has responded rapidly to global change in ozone and temperature\"

Matthew Koski, Drew MacQueen & Tia-Lynn Ashman
Across kingdoms, organisms ameliorate UV stress by increasing UV-absorbing pigmentation. Rapid ozone degradation during the 20th century resulted in elevated UV incidence, yet pigmentation responses to this aspect of global change have yet to be demonstrated. In flowering plants, UV exposure favors larger areas of UV-absorbing pigmentation on petals, which protects pollen from UV-damage. Pigmentation also affects floral thermoregulation, suggesting climate warming may additionally impact pigmentation. We used 1238 herbarium specimens collected from 1941 to...

Floral spectral reflectance data for: Floral color properties of serpentine seep assemblages depend on community size and species richness

Kathryn LeCroy, Gerardo Arceo-Gómez, Matthew Koski, Nathan Morehouse & Tia-Lynn Ashman
Functional traits, particularly those that impact fitness, can shape the ecological and evolutionary relationships among coexisting species of the same trophic level. Thus, examining these traits and properties of their distributions (underdispersion, overdispersion) within communities can provide insights into key ecological interactions (e.g., competition, facilitation) involved in community assembly. For instance, the distribution of floral colors in a community may reflect pollinator-mediated interactions between sympatric plant species, and the phylogenetic distribution of color can inform...

Audio recordings of Atelpus varius calls from Panama

Justin Kitzes, Samuel Lapp, Corinne Richards-Zawacki, Jamie Voyles, Keely Michelle Rodriguez & Tianhao Wu
Anurans (frogs and toads) are among the most globally threatened taxonomic groups. Successful conservation of anurans will rely on improved data on the status and changes in local populations, particularly for rare and threatened species. Automated sensors, such as acoustic recorders, have the potential to provide such data by massively increasing the spatial and temporal scale of population sampling efforts. We used AudioMoth autonomous recorders to survey for the critically endangered Harlequin toad (Atelopus varius)...

Worn region size of shoe outsole impacts human slips: Testing a mechanistic model

Kurt Beschorner, Vani H. Sundaram, Sarah L. Hemler, Arnab Chanda, Joel M. Haight & Mark S. Redfern
Shoe outsole tread wear has been shown to increase slip risk by reducing the tread’s ability to channel fluid away from the shoe-floor interface. This study establishes a connection between geometric features of the worn region size and slipping. A mechanistic pathway that describes the relationship between the worn region size and slip risk is assessed. Specifically, it is hypothesized that an increased worn region size leads to an increase in under-shoe fluid pressure, which...

Ericoid mycorrhizal shrubs alter the relationship between tree mycorrhizal dominance and soil carbon and nitrogen

Elisabeth Ward, Marlyse Duguid, Sara Kuebbing, James Lendemer, & Mark Bradford
1. Plant-fungal associations strongly influence forest carbon and nitrogen cycling. The prevailing framework for understanding these relationships is through the relative abundance of arbuscular (AM) versus ectomycorrhizal (EcM) trees. Ericoid mycorrhizal (ErM) shrubs are also common in forests and interactions between co-occurring ErM shrubs and AM and EcM trees could shift soil biogeochemical responses. Here we test hypotheses that the effects of ErM shrubs on soil carbon and nitrogen either extend or are redundant with...

Data from: Carotenoids and amphibians: effects on life history and susceptibility to the infectious pathogen, Batrachochytrium dendrobatidis

Rickey D. Cothran, Stephanie S. Gervasi, Cindy Murray, Beverly J. French, Paul W. Bradley, Jenny Urbina, Andrew R. Blaustein & Rick A. Relyea
Carotenoids are considered beneficial nutrients because they provide increased immune capacity. Although carotenoid research has been conducted in many vertebrates, little research has been done in amphibians, a group that is experiencing global population declines from numerous causes, including disease. We raised two amphibian species through metamorphosis on three carotenoid diets to quantify the effects on life-history traits and post-metamorphic susceptibility to a fungal pathogen (Batrachochytrium dendrobatidis; Bd). Increased carotenoids had no effect on survival...

Data from: Differential requirements for the RAD51 paralogs in genome repair and maintenance in human cells

Edwige B. Garcin, Stéphanie Gon, Meghan R. Sullivan, Gregory J. Brunette, Anne De Cian, Jean-Paul Concordet, Carine Giovannangeli, Wilhelm G. Dirks, Sonja Eberth, Kara A. Bernstein, Rohit Prakash, Maria Jasin & Mauro Modesti
Deficiency in several of the classical human RAD51 paralogs [RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3] is associated with cancer predisposition and Fanconi anemia. To investigate their functions, isogenic disruption mutants for each were generated in non-transformed MCF10A mammary epithelial cells and in transformed U2OS and HEK293 cells. In U2OS and HEK293 cells, viable ablated clones were readily isolated for each RAD51 paralog; in contrast, with the exception of RAD51B, RAD51 paralogs are cell-essential in MCF10A...

Data from: Analysis of inbreeding depression in mixed-mating plants provides evidence for selective interference and stable mixed mating

Alice A Winn, Elizabeth Elle, Susan Kalisz, Pierre-Olivier Cheptou, Christopher G Eckert, Carol Goodwillie, Mark O. Johnston, David A Moeller, Richard H Ree, Risa D Sargent & Mario Vallejo-Marín
Hermaphroditic individuals can produce both selfed and outcrossed progeny, termed mixed mating. General theory predicts that mixed-mating populations should evolve quickly toward high rates of selfing, driven by rapid purging of genetic load and loss of inbreeding depression (ID), but the substantial number of mixed-mating species observed in nature calls this prediction into question. Greater average ID reported for selfing than for outcrossing populations is consistent with purging and suggests that mixed-mating taxa in evolutionary...

Data from: Extremely long-distance seed dispersal by an overfished Amazonian frugivore

Jill T. Anderson, Tim Nuttle, Joe S. Saldaña Rojas, Thomas H. Pendergast & Alexander S. Flecker
Throughout Amazonia, overfishing has decimated populations of fruit-eating fishes, especially the largebodied characid, Colossoma macropomum. During lengthy annual floods, frugivorous fishes enter vast Amazonian floodplains, consume massive quantities of fallen fruits and egest viable seeds. Many tree and liana species are clearly specialized for icthyochory, and seed dispersal by fish may be crucial for the maintenance of Amazonian wetland forests. Unlike frugivorous mammals and birds, little is known about seed dispersal effectiveness of fishes. Extensive...

Data from: The evolution of floral sonication, a pollen foraging behavior used by bees (Anthophila)

Sophie Cardinal, Stephen L. Buchmann & Avery Leigh Russell
Over 22,000 species of biotically pollinated flowering plants, including some major agricultural crops, depend primarily on bees capable of floral sonication for pollination services. The ability to sonicate (“buzz”) flowers is widespread in bees but not ubiquitous. Despite the prevalence of this pollinator behavior and its importance to natural and agricultural systems, the evolutionary history of floral sonication in bees has not been previously studied. Here, we reconstruct the evolutionary history of floral sonication in...

Data from: Glucocorticoid-environment relationships align with responses to environmental change in two co-occurring congeners

Talisin T. Hammond, Rupert Palme & Eileen A. Lacey
As more species undergo range shifts in response to climate change, it is increasingly important to understand the factors that determine an organism’s realized niche. Physiological limits imposed by abiotic factors constrain the distributions of many species. Because glucocorticoids are essential to the maintenance of physiological homeostasis, identifying glucocorticoid-environment relationships may generate critical insights into both limits on species distributions and potential responses to environmental change. We explored relationships between variability in baseline glucocorticoids and...

Data from: Adaptation, chance, and history in experimental evolutionary reversals to unicellularity

María Rebolleda-Gómez & Michael Travisano
Evolution is often deemed irreversible. The evolution of complex traits that require many mutations makes their reversal unlikely. Even in simpler traits, reversals might become less likely as neutral or beneficial mutations, with deleterious effects in the ancestral context, become fixed in the novel background. This is especially true in changes that involve large re-organizations of the organism and its interactions with the environment. The evolution of multicellularity involves the reorganization of previously autonomous cells...

Data from: The Achilles' heel hypothesis: misinformed keystone individuals impair collective learning and reduce group success

Jonathan Pruitt, Colin Wright, Carl Keiser, Alexander DeMarco, Matt Grobis, Noa Pinter-Wollman, Matthew M. Grobis, Alex E. DeMarco, Carl N. Keiser, Jonathan N. Pruitt & Colin M. Wright
Many animal societies rely on highly influential keystone individuals for proper functioning. When information quality is important for group success, such keystone individuals have the potential to diminish group performance if they possess inaccurate information. Here we test whether information quality (accurate or inaccurate) influences collective outcomes when keystone individuals are the first to acquire it. We trained keystone or generic individuals to attack or avoid novel stimuli and implanted these seed individuals within groups...

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  • Cluster of Excellence livMatS, Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg, Georges-Köhler-Allee 105, 79110 Freiburg, Germany
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