20 Works

Fatal and non-fatal events within 14 days after early, intensive mobilization post stroke

Julie Bernhardt, Karen Borschmann, Janice Collier, Amanda Thrift, Peter Langhorne, Sandy Middleton, Richard Lindley, Helen Dewey, Philip Bath, Catherine Said, Leonid Churilov, Fiona Ellery, Christopher Bladin, Christopher Reid, Judith Frayne, Velandai Srikanth, Stephen Read & Geoffrey Donnan
Objective: We examined fatal and non-fatal Serious Adverse Events (SAEs) at 14 days within AVERT. Method: A prospective, parallel group, assessor blinded, randomized international clinical trial comparing very early intensive mobilization training (VEM) with usual care (UC); with follow up to 3 months. Included: Patients with ischaemic and haemorrhagic stroke within 24 hours of onset and physiological parameters within set limits. Treatment with thrombolytics allowed. Excluded: Patients with severe premorbid disability and/or comorbidities. Interventions continued...

Validation of an eDNA-based method for the detection of wildlife pathogens in water

Natalie Sieber, Hanna Hartikainen & Christoph Vorburger
Monitoring the occurrence and density of parasites and pathogens can identify high infection-risk areas and facilitates disease control and eradication measures. Environmental DNA (eDNA) techniques are increasingly used for pathogen detection due to their relative ease of application. Since many factors affect the reliability and efficacy of eDNA-based detection, rigorous validation and assessment of method limitations is a crucial first step. We evaluated an eDNA detection method using in-situ filtration of large volume water samples,...

Research data supporting \"Tetralin and decalin h-donor effect on catalytic upgrading of heavy oil inductively heated with steel balls\"

Abarasi Hart, Mohamed Adam, John Robinson, Sean Rigby & Joseph Wood
Dataset includes Thermogravimetric simulated distillation analysis, thermogravimetric coking data and nitrogen adsorption data of the catalyst.

Data from: Predator size affects the intensity of mutual interference in a predatory mirid

Nikos Papanikolaou, Sofia Dervisoglou, Argyro Fantinou, Theodore Kypraios, Valmari Giakoumaki & Dionysios Perdikis
Interference competition occurs when access to an available resource is negatively affected by interactions with other individuals, where mutual interference involves individuals of the same species. The interactive phenomena among individuals may be size-dependent, since body size is a major factor that may alter prey consumption rates and ultimately the dynamics and structure of food webs. A study was initiated in order to evaluate the effect of mutual interference in the prey-specific attack rates and...

Nucleotide alignments of eight meiosis genes under extreme selection following whole genome duplication in Arabidopsis lyrata/A.arenosa.

Paul Seear, Martin France, Catherine Gregory, Darren Heavens, Roswitha Schmickl, Levi Yant & James Higgins
In this study we performed a genotype-phenotype association analysis of meiotic stability in ten autotetraploid Arabidopsis lyrata and A. lyrata/A. arenosa hybrid populations collected from the Wachau region and East Austrian Forealps. The aim was to determine the effect of eight meiosis genes under extreme selection upon adaptation to whole genome duplication. Individual plants were genotyped by high-throughput sequencing of the eight meiosis genes (ASY1, ASY3, PDS5b, PRD3, REC8, SMC3, ZYP1a/b) implicated in synaptonemal complex...

Data from: Co-foundress confinement elicits kinship effects in a naturally sub-social parasitoid

Ian C. W. Hardy, Daniela Lupi & Mohamed K. Abdi
Kinship among interacting individuals is often associated with sociality and also with sex ratio effects. Parasitoids in the bethylid genus Goniozus are sub-social, with single foundress females exhibiting post-ovipositional maternal care via short-term aggressive host and brood defence against conspecific females. Due to local mate competition (LMC) and broods normally being produced by a single foundress, sex ratios are female biased. Contests between adult females are, however, not normally fatal and aggression is reduced when...

Diversification in evolutionary arenas – assessment and synthesis

Nicolai M. Nürk, H. Peter Linder, Renske E. Onstein, Matthew J. Larcombe, Colin E. Hughes, Laura Piñeiro Fernández, Philipp M. Schlüter, Luis Valente, Carl Beierkuhnlein, Vanessa Cutts, Michael J. Donoghue, Erika J. Edwards, Richard Field, Suzette G.A. Flantua, Steven I. Higgins, Anke Jentsch, Sigrid Liede-Schumann & Michael D. Pirie
Understanding how and why rates of evolutionary diversification vary is a central issue in evolutionary biology, ecology and biogeography. The concept of adaptive radiation has attracted much interest, but is metaphorical and verbal in nature, making it difficult to quantitatively compare different evolutionary lineages or geographic regions. In addition, the causes of evolutionary stasis are relatively neglected. Here we review the central concepts in the evolutionary diversification literature and bring these together by proposing a...

Data from: Courtship behaviour, nesting microhabitat and assortative mating in sympatric stickleback species-pairs

Laura Dean, Amelia Reddish, Hannah Dunstan & Andrew MacColl
The maintenance of reproductive isolation in the face of gene-flow is a particularly contentious topic, but differences in reproductive behaviour may provide the key to explaining this phenomenon. However, we do not yet fully understand how behaviour contributes to maintaining species boundaries. How important are behavioural differences during reproduction? To what extent does assortative mating maintain reproductive isolation in recently diverged populations and how important are ‘magic traits’? Assortative mating can arise as a by-product...

Research data supporting \"Operando visualisation of battery chemistry and dendrite formation in a sodium ion battery by 23Na MRI\"

Melanie Britton, Claire Doswell, Josh Bray, Galina Pavlovskaya, Emma Kendrick, Brij Kishore, Lin Chen, Maria-Magdalene Titirici, Heather Au, Hande Alptekin & Thomas Meersmann
Data for the figures in the manuscript and supplementary information.

Data from Reis et al (2020) Causes and consequences of liana infestation in Southern Amazonia. Journal of Ecology DOI: 10.1111/1365-2745.13470

Simone Matias Reis, Beatriz Schwantes Marimon, Paulo S. Morandi, Fernando Elias, Adriane Esquivel‐Muelbert, Ben Hur Marimon Junior, Sophie Fauset, Edmar Almeida de Oliveira, Geertje M.F. van der Heijden, David Galbraith, Ted R. Feldpausch & Oliver L. Phillips

Rethinking megafauna

Marcos Moleón, José Sánchez-Zapata, José Donázar, Eloy Revilla, Berta Martín-López, Cayetano Gutiérrez-Cánovas, Wayne Getz, Zebensui Morales-Reyes, Ahimsa Campos-Arceiz, Larry Crowder, Mauro Galetti, Manuela González-Suárez, Fengzhi He, Pedro Jordano, Rebecca Lewison, Robin Naidoo, Norman Owen-Smith, Nuria Selva, Jens-Christian Svenning, José Tella, Christiane Zarfl, Sonja Jähnig, Matt Hayward, Søren Faurby, Nuria García … & Klement Tochner
Concern for megafauna is increasing among scientists and non-scientists. Many studies have emphasized that megafauna play prominent ecological roles and provide important ecosystem services to humanity. But, what precisely are “megafauna”? Here we critically assess the concept of megafauna and propose a goal-oriented framework for megafaunal research. First, we review definitions of megafauna and analyze associated terminology in the scientific literature. Second, we conduct a survey among ecologists and paleontologists to assess the species traits...

The clinical impact of high-profile animal-based research reported in the UK national press: a detailed discussion of articles from 1995, and full search results from the Nexis database

Jarrod Bailey & Michael Balls
Objectives: We evaluated animal-based biomedical ‘breakthroughs’ reported in the UK national press in 1995 (25 years prior to the conclusion of this study). Based on evidence of over-speculative reporting of biomedical research in other areas (e.g. press releases and scientific papers), we specifically examined animal research in the media, asking, “In a given year, what proportion of animal research ‘breakthroughs’ published in the UK national press had translated, more than 20 years later, to approved...

Data associated with “Asymmetric magnetic relaxation behavior of domains and domain walls observed through the FeRh first-order metamagnetic phase transition”

Jamie Massey, Rowan Temple, Trevor Almeida, Ray Lamb, Nicolas Peters, Richard Campion, Fan Raymond, Damien McGrouther, Stephen McVitie, Paul Steadman & Christopher Marrows
Open access data deposit to accompany the publication “Asymmetric magnetic relaxation behavior of domains and domain walls observed through the FeRh first-order metamagnetic phase transition”

Intraspecific genomic variation and local adaptation in a young hybrid species

Angelica Cuevas, Mark Ravinet, Glenn-Peter Sætre & Fabrice Eroukhmanoff
Hybridization increases genetic variation, hence hybrid species may have greater evolutionary potential once their admixed genomes have stabilized and incompatibilities have been purged. Yet, little is known about how such hybrid lineages evolve at the genomic level following their formation, in particular their adaptive potential. Here we investigate how the Italian sparrow (Passer italiae), a homoploid hybrid species, has evolved and locally adapted to its variable environment. Using restriction site-associated DNA sequencing (RAD-seq) on several...

Data from: Hurricane effects on Neotropical lizards span geographic and phylogenetic scales

Colin Donihue, Alex Kowaleski, Jonathan Losos, Adam Algar, Simon Baeckens, Robert Buchkowski, Anne-Claire Fabre, Hannah Frank, Anthony Geneva, Graham Reynolds, James Stroud, Julián Velasco, Jason Kolbe, Luke Mahler & Anthony Herrel
Extreme climate events such as droughts, cold snaps, and hurricanes can be powerful agents of natural selection, producing acute selective pressures very different from the everyday pressures acting on organisms. However, it remains unknown whether these infrequent but severe disruptions are quickly erased by quotidian selective forces, or whether they have the potential to durably shape biodiversity patterns across regions and clades. Here, we show that hurricanes have enduring evolutionary impacts on the morphology of...

Aboveground carbon density plots from a logged forest, Danum Valley, Borneo, 1992-2016

M.E.J. Cutler, C.D. Philipson, D.F.R.P. Burslem, G.M. Foody, P. Lincoln, M.A. Pinard, M. Snoep, C.E. Wheeler, H. Tangki & Y.S. Wai
Data are presented for Above ground Carbon Density (ACD) estimated from a series of forest census surveys which took place from 1992 – 2016 in a mixture of logged and unlogged tropical lowland dipterocarp forest in the Ulu Segama Forest Reserve (USFR) and Danum Valley Conservation Area (DVCA), Sabah, Malaysia. Additional data on logging method, coupe and year of logging is also presented. The USFR comprises of forested land divided into coupes that were each...

Relationships between immune gene expression and circulating cytokine levels in wild house mice

Stuart Young, Jonathan Fenn, Elena Arriero, Ann Lowe, Benoit Poulin, Andrew MacColl & Jan Bradley
1. Quantitative PCR (qPCR) has been commonly used to measure gene expression in a number of research contexts, but the measured RNA concentrations do not always represent the concentrations of active proteins which they encode. This can be due to transcriptional regulation or post-translational modifications, or localisation of immune environments, as can occur during infection. However, in studies using free-living non-model species, such as in ecoimmunological research, qPCR may be the only available option to...

The impact of smoking status on the efficacy of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review

Kimberley Sonnex, Hanna Alleemudder & Roger Knaggs
Objectives: Inhaled corticosteroids (ICS) reduce exacerbation rates and the decline in lung function in people with chronic obstructive pulmonary disease (COPD). There is evidence that smoking causes ‘steroid resistance’ and thus reduces the effect of ICS. This systematic review aimed to investigate the effect of smoking on efficacy of ICS in COPD in terms of lung function and exacerbation rates. Design: Systematic review Data Sources: An electronic database search of PubMed, Ovid Medline, Ovid Embase...

Prior exposure to long day photoperiods alters immune responses and increases susceptibility to parasitic infection in stickleback

James Whiting, Muayad Mahmud, Janette Bradley & Andrew MacColl
Seasonal disease and parasitic infection are common across organisms, including humans, and there is increasing evidence for intrinsic seasonal variation in immune systems. Changes are orchestrated through organisms’ physiological clocks using cues such as day length. Ample research in diverse taxa has demonstrated multiple immune responses are modulated by photoperiod, but to date, there have been few experimental demonstrations that photoperiod cues alter susceptibility to infection. We investigated the interactions among photoperiod history, immunity, and...

Registration Year

  • 2020

Resource Types

  • Dataset


  • University of Nottingham
  • University of Birmingham
  • University of Glasgow
  • University of Leeds
  • Complutense University of Madrid
  • Yale University
  • University of Exeter
  • Estación Biológica de Doñana
  • Bangor University
  • Plymouth University