34 Works

Data from: The Pillars of Hercules as a bathymetric barrier to gene-flow promoting isolation in a global deep-sea shark (Centroscymnus coelolepis)

Diana Catarino, Halvor Knutsen, Ana Veríssimo, Esben Moland Olsen, Per Erik Jorde, Gui Menezes, Hanne Sannæs, David Stanković, Joan Batista Company, Francis Neat, Roberto Danovaro, Antonio Dell'Anno, Bastien Rochowski, Sergio Stefanni, Joan Baptista Company & Hanne Sannaes
Knowledge of the mechanisms limiting connectivity and gene-flow in deep-sea ecosystems is limited, especially for deep-sea sharks. The Portuguese dogfish (Centroscymnus coelolepis) is a globally distributed and Near Threatened deep-sea shark. C. coelolepis population structure was studied using 11 nuclear microsatellite markers and a 497 bp fragment from the mtDNA Control Region. High levels of genetic homogeneity across the Atlantic (ΦST=-0.0091, FST= 0.0024, P > 0.05) were found suggesting one large population unit at this...

Data from: Trait anticipatory pleasure predicts effort expenditure for reward

Joachim T. Geaney, Michael T. Treadway & Luke D. Smillie
Research in motivation and emotion has been increasingly influenced by the perspective that processes underpinning the motivated approach of rewarding goals are distinct from those underpinning enjoyment during reward consummation. This distinction recently inspired the construction of the Temporal Experience of Pleasure Scale (TEPS), a self-report measure that distinguishes trait anticipatory pleasure (pre-reward feelings of desire) from consummatory pleasure (feelings of enjoyment and gratification upon reward attainment). In a university community sample (N = 97),...

Data from: Blood-stage parasitaemia and age determine Plasmodium falciparum and P. vivax gametocytaemia in Papua New Guinea

Cristian Koepfli, Leanne J. Robinson, Patricia Rarau, Mary Salib, Naomi Sambale, Rahel Wampfler, Inoni Betuela, Wang Nuitragool, Alyssa E. Barry, Peter Siba, Ingrid Felger & Ivo Mueller
A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083 samples were collected in a cross-sectional survey in Papua New Guinea. Plasmodium species were detected by light microscopy and qPCR and gametocytes by detection of pfs25 and pvs25 mRNA transcripts by reverse-transcriptase PCR (qRT-PCR). The parasite prevalence by PCR was 18.5% for Plasmodium falciparum and 13.0% for P. vivax. 52.5% of all infections were...

Data from: Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model

Leanne J. Robinson, Rahel Wampfler, Inoni Betuela, Stephan Karl, Michael T. White, Connie S. N. Li Wai Suen, Natalie E. Hofmann, Benson Kiniboro, Andreea Waltmann, Jessica Brewster, Lina Lorry, Nandao Tarongka, Lornah Samol, Mariabeth Silkey, Quique Bassat, Peter M. Siba, Louis Schofield, Ingrid Felger, Ivo Mueller & Benson Kinboro
Background: The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine the contribution of relapses to the burden of P. vivax and P. ovale infection, illness, and transmission in Papua New Guinean children. Methods and Findings: From 17 August 2009 to 20 May 2010, 524 children aged 5–10 y from East Sepik Province in Papua...

Data from: Parasite and predator risk assessment: nuanced use of olfactory cues

John G. Sharp, Sarah Garnick, Mark A. Elgar & Graeme Coulson
Foraging herbivores face twin threats of predation and parasite infection, but the risk of predation has received much more attention. We evaluated, experimentally, the role of olfactory cues in predator and parasite risk assessment on the foraging behaviour of a population of marked, free-ranging, red-necked wallabies (Macropus rufogriseus). The wallabies adjusted their behaviour according to these olfactory cues. They foraged less, were more vigilant and spent less time at feeders placed in the vicinity of...

Data from: A global synthesis of survival estimates for microbats

Pia E. Lentini, Tomas J. Bird, Stephen R. Griffiths, Lisa N. Godinho & Brendan A. Wintle
Accurate survival estimates are needed to construct robust population models, which are a powerful tool for understanding and predicting the fates of species under scenarios of environmental change. Microbats make up 17% of the global mammalian fauna, yet the processes that drive differences in demographics between species are poorly understood. We collected survival estimates for 44 microbat species from the literature and constructed a model to determine the effects of reproductive, feeding and demographic traits...

Data from: High nucleotide diversity and limited linkage disequilibrium in Helicoverpa armigera facilitates the detection of a selective sweep

Sue V. Song, Sharon Downes, Tracey Parker, John G. Oakeshott & Charles Robin
Insecticides impose extreme selective pressures on populations of target pests and so insecticide resistance loci of these species may provide the footprints of ‘selective sweeps’. To lay the foundation for future genome-wide scans for selective sweeps and inform genome-wide association study designs, we set out to characterize some of the baseline population genomic parameters of one of the most damaging insect pests in agriculture worldwide, Helicoverpa armigera. To this end, we surveyed nine Z-linked loci...

Data from: Adoption in eastern grey kangaroos: a consequence of misdirected care?

Wendy J. King, David M. Forsyth, Graeme Coulson & Marco Festa-Bianchet
Adoption is rare in animals and is usually attributed to kin selection. In a 6-year study of eastern grey kangaroos (Macropus giganteus), 11 of 326 juveniles were adopted. We detected eight adoptions by observing behavioural associations and nursing between marked mothers and young and three more by analysing the relatedness of mothers and young using microsatellite DNA. Four adoptions involved reciprocal switches and three were by mothers whose own pouch young were known to subsequently...

Data from: Kinetic estimation of GFR improves prediction of dialysis and recovery after kidney transplantation

Timothy J. Pianta, Zoltan H. Endre, John W. Pickering, Nicholas A. Buckley & Philip W. Peake
Background: The early prediction of delayed graft function (DGF) would facilitate patient management after kidney transplantation. Methods: In a single-centre retrospective analysis, we investigated kinetic estimated GFR under non-steady-state conditions, KeGFR, in prediction of DGF. KeGFRsCr was calculated at 4h, 8h and 12h in 56 recipients of deceased donor kidneys from initial serum creatinine (sCr) concentrations, estimated creatinine production rate, volume of distribution, and the difference between consecutive sCr values. The utility of KeGFRsCr for...

Data from: Low evolutionary potential for egg-to-adult viability in Drosophila melanogaster at high temperatures

Torsten Nygaard Kristensen, Johannes Overgaard, Jan Lassen, Ary A. Hoffmann & Carla M. Sgro
To cope with the increasing and less predictable temperature forecasts under climate change, many terrestrial ectotherms will have to migrate or rely on adaptation through plastic or evolutionary means. Studies suggest that some ectotherms have a limited potential to change their upper thermal limits via evolutionary shifts, but research has mostly focused on adult life stages under laboratory conditions. Here we use replicate populations of Drosophila melanogaster and a nested half sib/full sib quantitative genetic...

Data from: A collection of Australian Drosophila datasets on climate adaptation and species distributions

Ary A. Hoffmann, Ailie Smith, Philippa C. Griffin & Sandra B. Hangartner
The Australian Drosophila Ecology and Evolution Resource (ADEER) collates Australian datasets on drosophilid flies, which are aimed at investigating questions around climate adaptation, species distribution limits and population genetics. Australian drosophilid species are diverse in climatic tolerance, geographic distribution and behaviour. Many species are restricted to the tropics, a few are temperate specialists, and some have broad distributions across climatic regions. Whereas some species show adaptability to climate changes through genetic and plastic changes, other...

Data from: Mother-offspring distances reflect sex differences in fine-scale genetic structure of eastern grey kangaroos

Wendy J. King, Dany Garant & Marco Festa-Bianchet
Natal dispersal affects life history and population biology and causes gene flow. In mammals, dispersal is usually male-biased so that females tend to be philopatric and surrounded by matrilineal kin, which may lead to preferential associations among female kin. Here we combine genetic analyses and behavioral observations to investigate spatial genetic structure and sex-biased dispersal patterns in a high-density population of mammals showing fission–fusion group dynamics. We studied eastern grey kangaroos (Macropus giganteus) over 2...

Data from: Mitochondrial DNA variants help monitor the dynamics of Wolbachia invasion into host populations

Heng Lin Yeap, Gordana Rašić, Nancy M. Endersby-Harshman, Siu F. Lee, Eggi Arguni, Hoang Le Nguyen & Ary A. Hoffmann
Wolbachia is the most widespread endosymbiotic bacterium of insects and other arthropods that can rapidly invade host populations. Deliberate releases of Wolbachia into natural populations of the dengue fever mosquito, Aedes aegypti, are used as a novel biocontrol strategy for dengue suppression. Invasion of Wolbachia through the host population relies on factors such as high fidelity of the endosymbiont transmission and limited immigration of uninfected individuals, but these factors can be difficult to measure. One...

Data from: Genomic evidence for role of inversion 3RP of Drosophila melanogaster in facilitating climate change adaptation

Rahul V. Rane, Lea Rako, Siu Fai Lee, Ary A. Hoffmann & Martin Kapun
Chromosomal inversion polymorphisms are common in animals and plants, and recent models suggest that alternative arrangements spread by capturing different combinations of alleles acting additively or epistatically to favour local adaptation. It is also thought that inversions typically maintain favoured combinations for a long time by suppressing recombination between alternative chromosomal arrangements. Here, we consider patterns of linkage disequilibrium and genetic divergence in an old inversion polymorphism in Drosophila melanogaster (In(3R)Payne) known to be associated...

Data from: Evolutionary potential of multiple measures of upper thermal tolerance in Drosophila melanogaster

Sandra Hangartner & Ary A. Hoffmann
Thermal tolerance influences the distribution and abundance of many species, but the adaptive capacity of species to increase upper thermal tolerance is poorly understood. Given that patterns of heat tolerance can strongly depend on assay method, it is crucial to get a better understanding of genetic variances and correlations among different heat tolerance components. This study tests for correlated responses in different heat tolerance assays in Drosophila melanogaster lines selected for increased heat tolerance following...

Data from: Effectiveness and safety of 1 vs 4 h blood pressure profile with clinical and laboratory assessment for the exclusion of gestational hypertension and pre-eclampsia: a retrospective study in a university affiliated maternity hospital

Elizabeth Anne McCarthy, Thomas A. Carins, Yolanda Hannigan, Nadia Bardien, Alexis Shub & Susan P. Walker
Objective: We asked whether 60 compared with 240 min observation is sufficiently informative and safe for pregnancy day assessment (PDAC) of suspected pre-eclampsia (PE). Design: A retrospective study of 209 pregnant women (475 PDAC assessments, 6 months) with routinely collected blood pressure (BP), symptom and laboratory information. We proposed a 60 min screening algorithm comprising: absence of symptoms, normal laboratory parameters and ≤1high-BP reading (systolic blood pressure, SBP 140 mm Hg or higher or diastolic...

Data from: Plasmodium vivax diversity and population structure across four continents

Cristian Koepfli, Priscila T. Rodrigues, Tiago Antao, Pamela Orjuela-Sánchez, Peter Van Den Eede, Dionicia Gamboa, Nguyen Van Hong, Jorge Bendezu, Annette Erhart, Céline Barnadas, Arsène Ratsimbasoa, Didier Menard, Carlo Severini, Michela Menegon, Baki Y. M. Nour, Nadira Karunaweera, Ivo Mueller, Marcelo U. Ferreira, Ingrid Felger & Bakri Y. M. Nour
Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers was either generated or compiled from 841 isolates from four continents collected in 1999–2008. Diversity was highest in South-East Asia (mean allelic richness 10.0–12.8), intermediate in the South Pacific (8.1–9.9) Madagascar and Sudan (7.9–8.4), and lowest in South America and Central Asia (5.5–7.2). A...

Data from: Application of wMelPop Wolbachia strain to crash local populations of Aedes aegypti

Scott A. Ritchie, Michael Townsend, Chris J. Paton, Ashley G. Callahan & Ary A. Hoffmann
The endosymbiotic bacteria Wolbachia pipientis (wMel strain) has been successfully established in several populations of Aedes aegypti, the primary dengue vector. The virulent Wolbachia strain wMelPop is known to cause several pathological impacts (increased egg mortality, life shortening, etc.) reducing overall fitness in the mosquito Ae. aegypti. Increased egg mortality could substantially reduce egg banks in areas with a lengthy monsoonal dry season, and be employed to eliminate local populations. We tested this application under...

Data from: Functional responses of insectivorous bats to increasing housing density support 'land-sparing' rather than ‘land-sharing’ urban growth strategies

Fiona M. Caryl, Linda F. Lumsden, Rodney Van Der Ree & Brendan A. Wintle
Debates about ‘land-sparing’ and ‘land-sharing’ strategies for conserving biodiversity in cities provide an overly simplistic characterization of alternate planning options. Increased urbanization manifests in a number of ways and sophisticated analyses of how species respond to urban environments are required before generalizations about the relative merits of either planning strategy should be made. We investigated how insectivorous bats respond to housing density (a measure of urbanization intensity) and a range of habitat variables by modelling...

Data from: Measurement of systemic mitochondrial function in advanced primary open-angle glaucoma and Leber hereditary optic neuropathy

Nicole J. Van Bergen, Jonathan G. Crowston, Jamie E. Craig, Kathryn P. Burdon, Lisa S. Kearns, Shiwani Sharma, Alex W. Hewitt, David A. Mackey & Ian A. Trounce
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the selective and gradual loss of retinal ganglion cells (RGCs). Aging and increased intraocular pressure (IOP) are glaucoma risk factors; nevertheless patients deteriorate at all levels of IOP, implying other causative factors. Recent evidence presents mitochondrial oxidative phosphorylation (OXPHOS) complex-I impairments in POAG. Leber Hereditary Optic Neuropathy (LHON) patients suffer specific and rapid loss of RGCs, predominantly in young adult males, due to...

Data from: Ontogenetic and interspecific scaling of consumption in insects

James L. Maino & Michael R. Kearney
The uptake of resources from the environment is a basic feature of all life. Consumption rate has been found to scale with body size with an exponent close to unity across diverse organisms. However, past analyses have ignored the important distinction between ontogenetic and interspecific size comparisons. Using principles of dynamic energy budget theory, we present a mechanistic model for the body mass scaling of consumption, which separates interspecific size effects from ontogenetic size effects....

Data from: The emergent geography of biophysical dispersal barriers across the Indo-West Pacific

Eric A. Treml, Jason Roberts, Patrick N. Halpin, Hugh P. Possingham & Cynthia Riginos
Aim: To discover and evaluate potential dispersal barriers across the Indo-West Pacific Ocean and to develop spatially explicit hypotheses regarding the location of barriers and their capacity to filter taxa. Additionally, to compare model predictions with previously described barriers and build a more thorough understanding of the region's biogeographic patterns. Location: The reefs of the Indo-West Pacific Ocean, from 100 to 170°E and from 30°N to 30°S. Methods: A biophysical larval dispersal model was used...

Data from: Prescribed burning protects endangered tropical heathlands of the Arnhem Plateau, northern Australia

Brett P. Murphy, Mark A. Cochrane & Jeremy Russell-Smith
1. There are concerns that frequent intense fires are reducing biodiversity on the Arnhem Plateau within Kakadu National Park, northern Australia. Since the 1980s, prescribed burning in the early dry season has aimed to reduce the extent of late dry season wildfires. A programme of more strategic prescribed burning has been undertaken since 2007, aiming to increase intervals between fires affecting heathland and rain forest communities. 2. We assess the effectiveness of prescribed burning in...

Data from: Broadband onset inhibition can suppress spectral splatter in the auditory brainstem

Martin J. Spencer, David A. X. Nayagam, Janine C. Clarey, Antonio G. Paolini, Hamish Meffin, Anthony N. Burkitt & David B. Grayden
In vivo intracellular responses to auditory stimuli revealed that, in a particular population of cells of the ventral nucleus of the lateral lemniscus (VNLL) of rats, fast inhibition occurred before the first action potential. These experimental data were used to constrain a leaky integrate-and-fire (LIF) model of the neurons in this circuit. The post-synaptic potentials of the VNLL cell population were characterized using a method of triggered averaging. Analysis suggested that these inhibited VNLL cells...

Data from: The contrasting phylodynamics of human influenza B viruses

Dhanasekaran Vijaykrishna, Edward C. Holmes, Udayan Joseph, Mathieu Fourment, Yvonne C. F. Su, Rebecca Halpin, Raphael T. C. Lee, Yi-Mo Deng, Vithiagaran Gunalan, Xudong Lin, Tim Stockwell, Nadia B. Fedorova, Bin Zhou, Natalie Spirason, Denise K. Kühnert, Veronika Bošková, Tanja Stadler, Anna-Maria Costa, Dominic E. Dwyer, Q. Sue Huang, Lance C. Jennings, William Rawlinson, Sheena G. Sullivan, Aeron C. Hurt, Sebastian Maurer-Stroh … & Raphael TC Lee
A complex interplay of viral, host and ecological factors shape the spatio-temporal incidence and evolution of human influenza viruses. Although considerable attention has been paid to influenza A viruses, a lack of equivalent data means that an integrated evolutionary and epidemiological framework has until now not been available for influenza B viruses, despite their significant disease burden. Through the analysis of over 900 full genomes from an epidemiological collection of more than 26,000 strains from...

Registration Year

  • 2015

Resource Types

  • Dataset


  • University of Melbourne
  • University of Queensland
  • Monash University
  • Walter and Eliza Hall Institute of Medical Research
  • University of Basel
  • University of Sydney
  • Swiss Tropical and Public Health Institute
  • Université de Sherbrooke
  • Duke University
  • Papua New Guinea Institute of Medical Research