2 Works

WegenerNet climate station network Level 2 data

Juergen Fuchsberger, Gottfried Kirchengast, Christoph Bichler, Thomas Kabas & Armin Leuprecht
The WegenerNet weather and climate station network dataset provides highly space-time resolved measurements of meteorological parameters for two regions in the state of Styria, Austria. The WegenerNet Feldbach region is located in the southeast of Styria and has an extent of about 22 km x 16 km. It comprises 155 meteorological stations which are placed on a tightly spaced grid, with an average station density of 1 station per ~2 km². Data are available at...

Autoantibodies against the prion protein in individuals with PRNP mutations

Karl Frontzek, Manfredi Carta, Marco Losa, Mirka Epskamp, Georg Meisl, Alice Anane, Jean-Philippe Brandel, Ulrike Camenisch, Joaquín Castilla, Stéphane Haïk, Tuomas Knowles, Ewald Lindner, Andreas Lutterotti, Eric Vallabh Minikel, Ignazio Roiter, Jiri G. Safar, Raquel Sanchez-Valle, Dana Žáková, Simone Hornemann & Adriano Aguzzi
Objective. To determine whether naturally occurring autoantibodies against the prion protein are present in individuals with genetic prion disease mutations and controls, and if so, whether they are protective against prion disease. Methods. In this case-control study, we collected 124 blood samples from individuals with a variety of pathogenicPRNPmutations and 78 control individuals with a positive family history of genetic prion disease but lacking disease-associatedPRNPmutations. Antibody reactivity was measured using an indirect ELISA for the...

Registration Year

  • 2019
    2

Resource Types

  • Dataset
    2

Affiliations

  • University of Graz
    2
  • Sorbonne Paris Cité
    1
  • University of Cambridge
    1
  • Hospital Clinic of Barcelona
    1
  • University of Zurich
    1
  • CIC bioGUNE
    1
  • Treviso Tecnologia (Italy)
    1
  • Healthcare Foundation of New Jersey
    1
  • Case Western Reserve University
    1
  • Slovak University of Technology in Bratislava
    1