Additional file 7: Table S7. Differentially expressed genes that appeared in both RNA-seq data and the GSE159676 datasets

Additional file 1: Table S1. Ferroptosis-related genes.

Distributional data analysis, concerned with the statistical analysis of data objects consisting of random probability distributions in the framework of functional data analysis (FDA), has received considerable interest in recent years and is increasingly applied in various fields including engineering. Outlier detection and robustness are of great practical interest; however, these aspects remain unexplored for distributional data. To this end, this study focuses on density-valued outlier detection and its application in robust distributional regression. Specifically,...

Although members of the Mycobacterium tuberculosis complex (MTBC) exhibit high similarity, they are characterized by differences with respect to virulence, immune response, and transmissibility. To understand the virulence of these bacteria and identify potential novel therapeutic targets, we systemically investigated the total cell protein contents of virulent H37Rv, attenuated H37Ra, and avirulent M. bovis BCG vaccine strains at the log and stationary phases, based on tandem mass tag (TMT) quantitative proteomics. Data analysis revealed that...

Although members of the Mycobacterium tuberculosis complex (MTBC) exhibit high similarity, they are characterized by differences with respect to virulence, immune response, and transmissibility. To understand the virulence of these bacteria and identify potential novel therapeutic targets, we systemically investigated the total cell protein contents of virulent H37Rv, attenuated H37Ra, and avirulent M. bovis BCG vaccine strains at the log and stationary phases, based on tandem mass tag (TMT) quantitative proteomics. Data analysis revealed that...

Additional file 3. Differentially expressed protein data.

The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in vitro experiments. The expression profile of lncRNA-UCA1 was analyzed by genome-wide analysis from GSE146459. The cell counting Kit-8, colony formation, wound healing and transwell assays were performed to evaluate the effects of lncRNA-UCA1 in vitro. In addition, luciferase reporter assays were...

Additional file 1: Table S1. Baseline characteristics on death and MACE risks. Table S2. Baseline characteristics on LVEF and LVMI. Table S3. Relationship between metabolites and death risk. Table S4. Relationship between metabolites and MACE risk. Table S5. Multivariate Cox proportional hazards model for clinical outcomes. Table S6. Spearman correlation analysis between clinical factors and those metabolites associated with death risk. Table S7. Spearman correlation analysis between clinical factors and those metabolites associated with death...

Source data of XRD, .hkl file from 3D electron diffraction, and electrolysis data.

Subfornical organ (SFO) is vital in chronic kidney disease (CKD) progression caused by high salt levels. The current study investigated the effects of high salt on phosphoproteomic changes in SFO in CKD rats. 5/6 nephrectomized rats were fed a normal-salt diet (0.4%) (NC group) or a high-salt diet (4%) (HC group) for three weeks, while sham-operated rats were fed a normal-salt diet (0.4%) (NS group). For phosphoproteomic analysis of SFO in different groups, TiO2 enrichment,...

Additional file 2: Table S2. RNA-seq data of liver tissues of NAFLD patients and controls.

Additional file 3: Table S3. Results of GO enrichment on differentially expressed genes from RNA-seq data.

Additional file 5: Table S5. Results of KEGG enrichment on differentially expressed genes from GSE159676 datasets.

Additional file 6: Table S6. Results of GO enrichment on differentially expressed genes from GSE159676 datasets.

Additional file 9. Supplementary RNA sequencing results.

Additional file 4: Targets information of DM.

Retinitis pigmentosa (RP) constitutes a class of common inherited retinal dystrophies. Patients with RP and comorbid primary angle-closure glaucoma (PACG) have been described, but the relationship between the diseases remains unclear. This study investigated the clinical and genetic characteristics of Chinese patients with RP and comorbid PACG. Of 1356 patients with RP, we analyzed the genetic features of 39 RP patients with PACG using next-generation sequencing and reviewed their clinical characteristics. In total, 18 patients...

Additional file 4. Differentially metabolic substance data.

Additional file 4. Differentially metabolic substance data.

Additional file 1: Table S1. Ferroptosis-related genes.

Additional file 4: Table S4. The top 20 significantly KEGG pathways of RNA-seq data.

Additional file 6: Table S6. Results of GO enrichment on differentially expressed genes from GSE159676 datasets.

Source data of XRD, .hkl file from 3D electron diffraction, and electrolysis data.

A new genus and species, Burmorussus mirabilis, is described based on two specimens from the mid-Cretaceous Burmese amber, and considered to be a specialized parasitic wasp of wood-living hosts. The new taxon is characterized by an orussid-like ocellar crown, big eyes, antennae attached well above the clypeus, and antennal grooves or ventral transverse frontal carinae absent. Additionally, all legs carry a prominent lanceolate lobe on the 3rd tarsomere. A similar structure is found, but organized...

The genetic variation of the COI gene has a great effect on the final results of the species delimitation studies. However, little research has comprehensively investigated the genetic divergence in COI among Insecta. The fast-growing COI data in BOLD provide an opportunity for comprehensively appraising the genetic variation in COI among Insecta. We calculated the K2P distance of 64,414 insect species downloaded from BOLD. The match ratios of the clustering analysis based on different thresholds...