6 Works

Data from: Diploid hybrid origin of Ostryopsis intermedia (Betulaceae) in the Qinghai-Tibet Plateau triggered by Quaternary climate change

Bingbing Liu, Richard J. Abbott, Zhiqiang Lu, Bin Tian & Jianquan Liu
Despite the well known effects that Quaternary climate oscillations had on shaping intraspecific diversity, their role in driving homoploid hybrid speciation is less clear. Here we examine their importance in the putative homoploid hybrid origin and evolution of Ostryopsis intermedia, a diploid species occurring in the Qinghai-Tibet Plateau (QTP), a biodiversity hotspot. We investigated interspecific relationships between this species and its only other congeners, O. davidiana and O. nobilis, based on four sets of nuclear...

Data from: Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

Wei Jiang, Jing-Jie Tang, Hong-Hua Miao, Yu-Xiu Qu, Jie Qin, Jie Xu, Jinbo Yang, Bo-Liang Li & Bao-Liang Song
Somatic cell genetics is a powerful approach for unraveling the regulatory mechanism of cholesterol metabolism. However, it is difficult to identify the mutant gene(s) due to cells are usually mutagenized chemically or physically. To identify important genes controlling cholesterol biosynthesis, an unbiased forward genetics approach named validation-based insertional mutagenesis (VBIM) system was used to isolate and characterize the 25-hydroxycholesterol (25-HC)-resistant and SR-12813-resisitant mutants. Here we report that five mutant cell lines were isolated. Among which,...

Data from: Climatic adaptation and ecological divergence between two closely related pine species in Southeast China

Yongfeng Zhou, Lirui Zhang, Jianquan Liu, Guili Wu & Outi Savolainen
Climatic selection contributes greatly to local adaptation and intraspecific differentiation, but this kind of selection could have also promoted interspecific divergence through ecological speciation. In this study, we examined genetic variation within and between two closely related pine species, Pinus massoniana and Pinus hwangshanensis. These two species occur in Southeast China and exhibit contrasting ecological preferences, although hybrids are formed where their distributions overlap. We sampled 26 populations of the two species across their distributional...

Data from: Erythrocyte stiffness during morphological remodeling induced by carbon ion radiation

Baoping Zhang, Bin Liu, Hong Zhang & Jizeng Wang
The adverse effect induced by carbon ion radiation (CIR) is still an unavoidable hazard to the treatment object. Thus, evaluation of its adverse effects on the body is a critical problem with respect to radiation therapy. We aimed to investigate the change between the configuration and mechanical properties of erythrocytes induced by radiation and found differences in both the configuration and the mechanical properties with involving in morphological remodeling process. Syrian hamsters were subjected to...

Data from: Genome-wide variation within and between wild and domestic yak

Kun Wang, Quanjun Hu, Hui Ma, Lizhong Wang, Yongzhi Yang, Wenchun Luo & Qiang Qiu
The yak is one of the few animals that can thrive in the harsh environment of the Qinghai-Tibetan Plateau and adjacent alpine regions. Yak provide essential resources allowing Tibetans to live at high altitudes. However, genetic variation within and between wild and domestic yak remain unknown. Here, we present a genome-wide study of the genetic variation within and between wild and domestic yak. Using next-generation sequencing technology, we re-sequenced three wild and three domestic yak...

Data from: Transcriptome sequencing and phylogenomic resolution within Spalacidae (Rodentia)

Gong-Hua Lin, Kun Wang, Xiao-Gong Deng, Eviatar Nevo, Fang Zhao, Jian-Ping Su, Song-Chang Guo, Tong-Zuo Zhang & Huabin Zhao
Background: Subterranean mammals have been of great interest for evolutionary biologists because of their highly specialized traits for the life underground, however, the scarcity of genomic information limits our better understanding of their evolutionary history. Owing to the convergence of morphological traits and the incongruence of molecular data, the phylogenetic relationships among three subfamilies Myospalacinae (zokors), Spalacinae (blind mole rats) and Rhizomyinae (bamboo rats) within the family Spalacidae remain unresolved. Here, we performed de novo...

Registration Year

  • 2014

Resource Types

  • Dataset


  • Lanzhou University
  • Sichuan University
  • Shanghai Institutes for Biological Sciences
  • Institute of Biochemistry
  • University of Zurich
  • University of Haifa
  • University of St Andrews
  • Wuhan University
  • Chinese Academy of Sciences
  • Institute of Modern Physics