15 Works

Multimolecular characteristics of cell-death related hub genes in human cancers: a comprehensive pan-cancer analysis

Dingtao Hu, Tingyu Zhang, Ziye Yan, Linlin Wang, Yuhua Wang, Nana Meng, Bizhi Tu, Ying Teng, Zhen Li, Xiaoqi Lou, Yu Lei, Xiaoshuang Ren, Yanfeng Zou & Fang Wang
Failure of the normal process of cell death pathways contributes to the defection of immune systems and the occurrence of cancers. The key genes, the multimolecular mechanisms, and the immune functions of these genes in pan-cancers remain unclear. Using online databases of The Cancer Genome Atlas, GEPIA2, TISIDB, HPA, Kaplan-Meier Plotter, PrognoScan, cBioPortal, GSCALite, TIMER, and Sangerbox, we identified the key genes from the six primary cell death-related pathways and performed a comprehensive analysis to...

Developmental temperature alters the thermal sensitivity of courtship activity and signal-preference relationships, but not mating rates

Anthony Macchiano, Kasey D. Fowler-Finn, Em Miller, Uchechukwu Agali & Abisiola Ola-Ajose
Mating behaviours are susceptible to novel or stressful thermal conditions, particularly for ectothermic organisms. One way to deal with changes in thermal conditions is to exhibit developmental plasticity, whereby the thermal sensitivity of mating behaviours depend on developmental conditions. We test how developmental temperature affects the thermal sensitivity of courtship behaviour and mating rates, as well as mating signal and preference coupling. We rear treehoppers under two temperature regimes and then test how a range...

Data for: Evolutionary interactions between thermal ecology and sexual selection

Noah Leith, Kasey Fowler-Finn & Michael Moore
Thermal ecology and mate competition are both pervasive features of ecological adaptation. A surge of recent work has uncovered the diversity of ways in which temperature affects mating interactions and sexual selection. However, the potential for thermal biology and reproductive ecology to evolve together as organisms adapt to their thermal environment has been underappreciated. Here, we develop a series of hypotheses regarding (1) not only how thermal ecology affects mating system dynamics, but also how...

Interspecific hybridization and island colonization history, not rarity, most strongly affect the genetic diversity in a clade of Mascarene-endemic trees

Alexander Linan, Christine Edwards, George Schatz, Porter Lowry, Allison Miller & Jean Claude Sevathian
Many factors shape the genetic diversity of island-endemic trees, with important implications for conservation. Oceanic island-endemic lineages undergo an initial founding bottleneck during the colonization process and subsequently accumulate diversity following colonization. Moreover, many island endemics occur in small populations and are further threatened by anthropogenic factors that cause population declines, making them susceptible to losses in genetic diversity through genetic drift, inbreeding, and bottlenecks. However, life-history traits commonly found in trees, such as outcrossing...

Light environment interacts with visual displays in a species-specific manner in multimodal signaling wolf spiders

Rowan McGinley, James Starrett, Jason Bond & Eileen Hebets
Light availability is highly variable, yet predictable, over various timescales and the light environment is expected to play an important role in the evolution of visual signals. Courtship displays within the wolf spider genus Schizocosa always involve the use of substrate borne vibrations, however, there is substantial variation between species in the use of visual displays. We assessed the impact of light intensity on the courtship of four species of Schizocosa that vary in their...

Temperature and mating in harvestmen

Kasey Fowler-Finn & Todd Johnson
Temperature impacts a wide range of mating behaviours, particularly in ectothermic organisms that tend to havebody temperatures similar to ambient thermal conditions. Here, we test the effects of thermal variation on precopulatory and copulatory behaviour in the harvester Leiobunum politum Weed 1889, which belongs to the group commonly known as daddy longlegs. We ran single choice mating trials across temperatures commonly experienced in the field during the mating season (18 - 34 °C) across two...

Increases in vein length compensate for leaf area lost to lobing in grapevine

Zoë Migicovsky, Joel F. Swift, Zachary Helget, Laura L. Klein, Anh Ly, Matthew Maimaitiyiming, Karoline Woodhouse, Anne Fennell, Misha Kwasniewski, Allison J. Miller, Peter Cousins & Daniel H. Chitwood
There is considerable variation in leaf lobing and leaf size, including among grapevines, some of the most well-studied leaves. We examined the relationship between leaf lobing and leaf size across grapevine populations which varied in extent of leaf lobing. We used homologous landmarking techniques to measure 2,632 leaves across two years in 476 unique, genetically distinct grapevines from 5 biparental crosses which vary primarily in the extent of lobing. We determined to what extent leaf...

ACPY2 gene polymorphisms on cancer risk: a systematic review and meta-analysis

Xueliang Chang, Zhan Yang, Hu Wang, Yaxuan Wang, Jingdong Li, Yanping Zhang, Zhihai Teng & Zhenwei Han
To provide a comprehensive account of the association of ACYP2 gene polymorphisms with susceptibility to cancer. A literature search for eligible candidate gene studies published before April 20, 2022 was conducted in the PubMed, Medline and Web of Science. The following combinations of main keywords were used: (ACYP2 OR acylphosphatase 2) AND (polymorphism OR mutation OR variation OR SNP OR genotype) AND (cancer OR tumor OR neoplasm OR malignancy OR carcinoma OR adenocarcinoma). Potential sources...

ACPY2 gene polymorphisms on cancer risk: a systematic review and meta-analysis

Xueliang Chang, Zhan Yang, Hu Wang, Yaxuan Wang, Jingdong Li, Yanping Zhang, Zhihai Teng & Zhenwei Han
To provide a comprehensive account of the association of ACYP2 gene polymorphisms with susceptibility to cancer. A literature search for eligible candidate gene studies published before April 20, 2022 was conducted in the PubMed, Medline and Web of Science. The following combinations of main keywords were used: (ACYP2 OR acylphosphatase 2) AND (polymorphism OR mutation OR variation OR SNP OR genotype) AND (cancer OR tumor OR neoplasm OR malignancy OR carcinoma OR adenocarcinoma). Potential sources...

Data from: Increased signal complexity is associated with increased mating success

Noori Choi, Matt Adams, Kasey Fowler-Finn, Elise Knowlton, Malcolm Rosenthal, Aaron Rundus, Roger Santer, Dustin Wilgers & Eileen Hebets
The evolution of complex signaling has often been explored by testing multiple functional hypotheses that vary in their underlying assumptions about how independent signal components provide selective benefits to offset the costs of their production. In the present study, we take a different approach to exploring the function of complexity per se. We test the hypothesis that increased vibratory signal complexity – based on both proportional and temporal patterning - provides selective benefits to courting...

Multimolecular characteristics of cell-death related hub genes in human cancers: a comprehensive pan-cancer analysis

Dingtao Hu, Tingyu Zhang, Ziye Yan, Linlin Wang, Yuhua Wang, Nana Meng, Bizhi Tu, Ying Teng, Zhen Li, Xiaoqi Lou, Yu Lei, Xiaoshuang Ren, Yanfeng Zou & Fang Wang
Failure of the normal process of cell death pathways contributes to the defection of immune systems and the occurrence of cancers. The key genes, the multimolecular mechanisms, and the immune functions of these genes in pan-cancers remain unclear. Using online databases of The Cancer Genome Atlas, GEPIA2, TISIDB, HPA, Kaplan-Meier Plotter, PrognoScan, cBioPortal, GSCALite, TIMER, and Sangerbox, we identified the key genes from the six primary cell death-related pathways and performed a comprehensive analysis to...

Genome and annotation of triploid cultivated banana

Xiuxiu Li, Sheng Yu, Zhihao Cheng, Yingzi Yun, Xuequn Chen, Xing Liu, Hua Li, Wenjun Zhu, Shiyao Xu, Yanbing Xu, Chen Zhang, Xianjun Wang, Xingtan Zhang, Zhenguo Lin, Jean-Marc Aury, Yves Van de Peer, Zonghua Wang, Xiaofan Zhou, Peitao Lü & Liangsheng Zhang
Genome assemblies and annotations of Cavendish and Gros Michel bananas

Swimming and schooling data of golden shiners in variable water temperatures

Maria Kuruvilla, Anthony Dell, Ashley R. Olson, Jason Knouft, John Grady, Jacob Forbes & Andrew Berdahl
Temperature is highly influential on the physiology and behaviour of ectotherms. In fish, temperature affects social interactions such as schooling behaviour, a common defence against predation. However, the effect of temperature on the ability of schooling fish to collectively respond to a predator is unknown. Here we used a loom stimulus to simulate an approaching predator that elicited a fleeing response in schooling fish over a range of water temperatures (9-29°C) and group sizes (1-16...

Dataset for: Water, environment, and socioeconomic justice in California: A multi-benefit cropland repurposing framework

Angel Santiago Fernandez-Bou, José Manuel Rodríguez-Flores, Alexander Guzman, J. Pablo Ortiz-Partida, Leticia Margarita Classen-Rodriguez, Humberto Florez-Landeros, Jorge Valero-Fandiño, Chantelise Pells, Thomas Harmon & Josué Medellín-Azuara
Low-income, rural frontline communities of California’s Central Valley experience environmental and socioeconomic injustice, water insecurity, extremely poor air quality, and lack of fundamental infrastructure (sewage, green areas, health services), which makes them less resilient. Many communities depend financially on agriculture, while water scarcity and associated policy may trigger farmland retirement, further hindering socioeconomic opportunities. Here we propose a multi-benefit framework to repurpose cropland in buffers inside and around (400-m and 1600-m buffers) 154 rural disadvantaged...

Genome and annotation of triploid cultivated banana

Xiuxiu Li, Sheng Yu, Zhihao Cheng, Yingzi Yun, Xuequn Chen, Xing Liu, Hua Li, Wenjun Zhu, Shiyao Xu, Yanbing Xu, Chen Zhang, Xianjun Wang, Xingtan Zhang, Zhenguo Lin, Jean-Marc Aury, Yves Van de Peer, Zonghua Wang, Xiaofan Zhou, Peitao Lü & Liangsheng Zhang
Genome assemblies and annotations of Cavendish and Gros Michel bananas

Registration Year

  • 2022
    15

Resource Types

  • Dataset
    15

Affiliations

  • Saint Louis University
    15
  • Fudan University
    4
  • Shanxi Medical University
    4
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    4
  • Shanghai Jiao Tong University
    3
  • Peking University First Hospital
    3
  • South China University of Technology
    3
  • Beijing Tian Tan Hospital
    2
  • Henan University
    2
  • New York University Langone Medical Center
    2