11 Works

Data from: Ultrasonic cavitation induces necrosis and impairs growth in three-dimensional models of pancreatic ductal adenocarcinoma

Einas Abou Ali, Benoit Bordacaha, Jean-Louis Mestas, Frederic Batteux, Cyril Lafon, Marine Camus & Frederic Prat
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a rapidly increasing cause of mortality whose dismal prognosis is mainly due to overwhelming chemoresistance. New therapeutic approaches include physical agents such as ultrasonic cavitation, but clinical applications require further insights in the mechanisms of cytotoxicity. Three dimensional in vitro culture models such as spheroids exploit realistic spatial, biochemical and cellular heterogeneity that may bridge some of the experimental gap between conventional in vitro and in vivo experiments. Purpose:...

Data from: Exploring and visualising spaces of tree reconciliations

Katharina T. Huber, Vincent Moulton, Marie-France Sagot & Blerina Sinaimeri
Tree reconciliation is the mathematical tool that is used to investigate the coevolution of organisms, such as hosts and parasites. A common approach to tree reconciliation involves specifying a model that assigns costs to certain events, such as cospeciation, and then tries to find a mapping between two specified phylogenetic trees which minimises the total cost of the implied events. For such models, it has been shown that there may be a huge number of...

Data from: Does multiple paternity explain phenotypic variation among offspring in wild boar?

Marlène Gamelon, Thibault Gayet, Eric Baubet, Sébastien Devillard, Ludovic Say, Serge Brandt, Christophe Pélabon & Bernt-Erik Sæther
During pregnancy, littermates compete to extract maternal resources from the placenta. Unequal extraction of resources leads to developmental differences among offspring and thus within-litter variation in offspring mass. Because competition among littermates can be stronger among half-sibs, multiple paternity may represent an adaptive strategy allowing females to increase within-litter phenotypic variation among offspring when facing variable environments. Wild boar (Sus scrofa) females produce large litters with diversified offspring in terms of body mass. Additionally, multiple...

Data from: Back and forth Wolbachia transfers reveal efficient strains to control spotted wing drosophila populations

Julien Cattel, Katerina Nikolouli, Thibault Andrieux, Julien Martinez, Francis Jiggins, Sylvain Charlat, Fabrice Vavre, David Lejon, Patricia Gibert & Laurence Mouton
1.Since its recent invasion of the European and American continents, the spotted wing Drosophila Drosophila suzukii has become a burden of the fruit industry. Armed with a highly sclerotized ovipositor, females can lay eggs in a wider variety of ripening and healthy fruits than other Drosophila species. Economic losses due to Drosophila suzukii reach millions of dollars annually and methods to control natural populations in the field mainly rely on the use of chemical pesticides....

Data from: Transient growth-enhancing effects of elevated maternal thyroid hormones at no apparent oxidative cost during early postnatal period

Bin-Yan Hsu, Blandine Doligez, Lars Gustafsson & Suvi Ruuskanen
Maternal thyroid hormones (THs) have been proven crucial for embryonic development in humans, but their influence within the natural variation on wild animals remains unknown. So far the only two studies that experimentally investigated the potential fitness consequences of maternal THs in birds found inconsistent results. More studies are thus required to assess the general effects of maternal THs and their influences on more behavioral and physiological parameters. In this study, we experimentally elevated yolk...

Data from: Divergent in shape and convergent in function: adaptive evolution of the mandible in Sub-Antarctic mice

Sabrina Renaud, Ronan Ledevin, Benoît Pisanu, Jean-Louis Chapuis, Petra Quillfeldt & Emilie A. Hardouin
Convergent evolution in similar environments constitutes strong evidence of adaptive evolution. Transported with people around the world, house mice colonized even remote areas, such as Sub-Antarctic islands. There, they returned to a feral way of life, shifting towards a diet enriched in terrestrial macroinvertebrates. Here, we test the hypothesis that this triggered convergent evolution of the mandible, a morphological character involved in food consumption. Mandible shape from four Sub-Antarctic islands was compared to phylogeny, tracing...

Data from: Development of a PCR-RFLP assay to identify Drosophila melanogaster among field-collected larvae

Vincent Raquin, Hélène Henri, Marine Vallat, François Leulier, Patricia Gibert & Natacha Kremer
The fruit fly Drosophila melanogaster is a model organism to study several aspects of metazoan biology. Most of the work has been conducted in adult fruit flies, including laboratory and field-derived specimens, but Drosophila melanogaster larvae recently became a valuable model to better understand animal physiology, development or host-microbe interactions. While adult flies can be easily assigned to a given Drosophila species based on morphological characteristics, such visual identification is more intricate at the larval...

Data from: A local evaluation of the individual state-space to scale up Bayesian spatial capture recapture

Cyril Milleret, Pierre Dupont, Christophe Bonenfant, Henrik Brøseth, Øystein Flagstad, Chris Sutherland & Richard Bischof
1. Spatial capture-recapture models (SCR) are used to estimate animal density and to investigate a range of problems in spatial ecology that cannot be addressed with traditional non-spatial methods. Bayesian approaches in particular offer tremendous flexibility for SCR modelling. Increasingly, SCR data are being collected over very large spatial extents making analysis computational intensive, sometimes prohibitively so. 2. To mitigate the computational burden of large-scale SCR models, we developed an improved formulation of the Bayesian...

Data from: Effects of interspecific coexistence on laying date and clutch size in two closely related species of hole‐nesting birds

Anders Pape Møller, Javier Balbontin, André A. Dhondt, Vladimir Remeš, Frank Adriaensen, Clotilde Biard, Jordi Camprodon, Mariusz Cichoń, Blandine Doligez, Anna Dubiec, Marcel Eens, Tapio Eeva, Anne E. Goodenough, Andrew G. Gosler, Lars Gustafsson, Philipp Heeb, Shelley A. Hinsley, Staffan Jacob, Rimvydas Juškaitis, Toni Laaksonen, Bernard Leclercq, Bruno Massa, Tomasz D. Mazgajski, Rudi G. Nager, Jan-Åke Nilsson … & Ruedi G. Nager
Coexistence between great tits Parus major and blue tits Cyanistes caeruleus, but also other hole‐nesting taxa, constitutes a classic example of species co‐occurrence resulting in potential interference and exploitation competition for food and for breeding and roosting sites. However, the spatial and temporal variations in coexistence and its consequences for competition remain poorly understood. We used an extensive database on reproduction in nest boxes by great and blue tits based on 87 study plots across...

Data from: Circadian periodicity in space use by ungulates of temperate regions: how much, when, and why?

Guillaume Peron, Antoine Duparc, Mathieu Garel, Pascal Marchand, Nicolas Morellet, Sonia Said & Anne Loison
1. When they visit and revisit specific areas, animals may reveal what they need from their home range and how they acquire information. The temporal dimension of such movement recursions, i.e., periodicity, is however rarely studied, yet potentially bears a species, population, or individual-specific signature. 2. A recent method allows estimating the contribution of periodic patterns to the variance in a movement path. We applied it to 709 individuals from 5 ungulate species, looking for...

Data from: The influence of early-life allocation to antlers on male performance during adulthood: evidence from contrasted populations of a large herbivore

Jean-François Lemaître, Louise Cheynel, Frederic Douhard, Gilles Bourgoin, François Débias, Hubert Ferté, Emmanuelle Gilot-Fromont, Sylvia Pardonnet, Maryline Pellerin, Benjamin Rey, Cécile Vanpé, A.J. Mark Hewison, Jean-Michel Gaillard & A. J. Mark Hewison
1. To secure mating opportunities, males often develop and maintain conspicuous traits that are involved in intra-sexual and/or inter-sexual competition. While current models of sexual selection rely on the assumption that producing such traits is costly, quantifying the cost of allocating to secondary sexual traits remains challenging. 2. According to the principle of allocation, high energy allocation to growth or sexual traits in males should lead to reduced energy allocation to the maintenance of cellular...

Registration Year

  • 2018

Resource Types

  • Dataset


  • University of Lyon System
  • Office National de la Chasse et de la Faune Sauvage
  • French National Centre for Scientific Research
  • University of Toulouse
  • Sorbonne University
  • Uppsala University
  • University of Massachusetts Amherst
  • Centre d'Ecologie Fonctionnelle et Evolutive
  • University of Antwerp
  • Museum and Institute of Zoology