2 Works

Data from: Increase in CO2 concentration could alter the response of Hedera helix to climate change

Ruben D. Manzanedo, Juan Ballesteros-Cánovas, Floris Schenk, Markus Stoffel, Markus Fischer & Eric Allan
• Increasing CO2 concentrations ([CO2]) is likely to affect future species distributions, in interaction with other climate change drivers. However, current modelling approaches still seldom consider interactions between climatic factors and the importance of these interactions therefore remains mostly unexplored. • Here, we combined dendrochronological and modelling approaches to study the interactive effects of increasing [CO2] and temperature on the distribution of one of the main European liana species, Hedera helix. We combined a classical...

Data from: Systematic analysis of complex genetic interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda Van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius Jonas Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo … & Chad L. Myers
To systematically explore complex genetic interactions, we constructed ~200,000 yeast triple mutants and scored negative trigenic interactions. We selected double-mutant query genes across a broad spectrum of biological processes, spanning a range of quantitative features of the global digenic interaction network and tested for a genetic interaction with a third mutation. Trigenic interactions often occurred among functionally related genes, and essential genes were hubs on the trigenic network. Despite their functional enrichment, trigenic interactions tended...

Registration Year

  • 2018

Resource Types

  • Dataset


  • University of Geneva
  • The University of Texas at Austin
  • University of Minnesota
  • University of Bern
  • University of Toronto