Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N) and spike (S) protein after symptom onset in the intensive care unit (ICU) and non-ICU patients. 130 blood samples from 38 COVID-19 patients were collected. The levels of IgM and IgG specific to N and...

The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N) and spike (S) protein after symptom onset in the intensive care unit (ICU) and non-ICU patients. 130 blood samples from 38 COVID-19 patients were collected. The levels of IgM and IgG specific to N and...

Additional file 3. Differentially expressed protein data.

Additional file 6: Table S4. List of lipids in intramuscular fat correlated with ELOVL3 expression in pectorals.

Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 1: Table S1. Association analysis of 51 SNPs in the ELOVL gene family with growth, carcass and meat quality traits in Gushi ×Anka F2 chickens.

Additional file 4: Table S3. Putative ERE and AP1 element in chicken ELOVL genes promoter.

Additional file 1: Table S1. Association analysis of 51 SNPs in the ELOVL gene family with growth, carcass and meat quality traits in Gushi ×Anka F2 chickens.

Supplementary Material 1: Table S9 The HLR within 118 worldurban areas. Notes: The 118 world urban areas are selected onthe basis of area larger than 100 km2, being capitals, with populationsgreater than 1 million or have carbon monitoring sites.

Additional file 14 Supplementary Table 6. Target distribution analyses for sgRNAs used in Fig. 4.

Additional file 15 Supplementary Table 7. Primers used in Fig. 5.

Additional file 15 Supplementary Table 7. Primers used in Fig. 5.

Additional file 16 Supplementary Table 8. Fingerprints of the 216 Human KRAB-ZFPs on chr19.

Additional file 1. Table S1: Plant species and library information.

ABSTRACT Introduction The explosive power of the lower limbs is an indispensable index in soccer. Having a good level of explosive power establishes a solid foundation for the performance and the competitive level of soccer players. Objective Promote the conditions to improve the explosive level of soccer players and improve their performance and competitive level. Methods This paper presents the influence of compound strength training on the explosive power of the lower limbs of soccer...

ABSTRACT In high speed seeding operation, the random collisions of seeds in the seed delivery tube seriously affect the seeding accuracy. In order to improve seeding uniformity and stability in high speed operation, the seed delivery device with a rotating brush wheel was designed, including U-shaped groove seed tube and flexible brush wheel. The optimization experiment was carried out by quadratic-regression rotatable orthogonal design method in JPS-12 seeding performance test bench. The three main factors...

Long non-coding RNAs (lncRNAs) have been widely studied and play crucial roles in cervical cancer (CC) progression. Here, we investigated the function and mechanism of lncRNA PGM5-AS1 action in CC cells. Using real-time quantitative polymerase chain reaction or western blotting, PGM5-AS1 and decorin (DCN) were downregulated in CC tissues and cells, whereas miR-4284 was upregulated. Luciferase assay, RNA pull-down assay, and western blotting showed that PGM5-AS1 could sponge miR-4284 to upregulate DCN expression in CC...

The role of adhesion receptor integrin αvβ3 in T-ALL was unclear. Firstly, we performed quantitative real-time PCR to assess medullary expression of integrin β3(ITGB3) in T-ALL patients and high ITGB3 expression was relevant with the central nervous system leukemia(CNSL) incidence. Decreasing of cell invasion was observed in Jurkat and Molt4 treated with integrin αvβ3 specific antibody and inhibitor as well as cells with ITGB3 interference. Further, phosphorylation of FAK, cRAF, MEK and ERK decreased in...

Traditional Z-test methods during noninvasive prenatal screens (NIPS) use the fixed parameter of standard deviation (SD), which ignores the influence of actual sequencing read counts of a sample on the results. The aim of this study is to eliminate the influence of the sequencing depth of individual samples on the results and enhance the power of NIPS. In this study, we propose an improved NIPS method, which calculates the SD in the Z-score process adaptively...

Long non-coding RNAs (lncRNAs) are related to a variety of human diseases. However, little is known about the role of lncRNA in intervertebral disc degeneration (IDD). LncRNA expression profile of human IDD were downloaded from Gene Expression Omnibus (GEO) database. Potential biomarkers and therapeutic drugs for IDD were analyzed by weighted gene co-expression network analysis (WGCNA), R software package Limma, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). We identified 1455 differentially...

Although our previous research shows an ameliorated high-fat diet (HFD)-induced hepatic steatosis and insulin resistance in global SND1 transgenic mice, the involvement of SND1 loss-of-function in hepatic metabolism remains elusive. Herein, we aim to explore the potential impact of hepatocyte-specific SND1 deletion on insulin-resistant mice. As SND1 is reported to be linked to inflammatory response, the pathobiological feature of acute liver failure (ALF) is also investigated. Hence, we construct the conditional liver knockout (LKO) mice...

Although our previous research shows an ameliorated high-fat diet (HFD)-induced hepatic steatosis and insulin resistance in global SND1 transgenic mice, the involvement of SND1 loss-of-function in hepatic metabolism remains elusive. Herein, we aim to explore the potential impact of hepatocyte-specific SND1 deletion on insulin-resistant mice. As SND1 is reported to be linked to inflammatory response, the pathobiological feature of acute liver failure (ALF) is also investigated. Hence, we construct the conditional liver knockout (LKO) mice...

Additional file 10 Supplementary Table 2. The identity and frequency of all types of fingerprints in mouse KRAB-ZFP-associated ZnFs (information for Supplementary Fig. 3).