35 Works

Data from: Elastogravity waves and dynamic ground motions in the Korean Peninsula generated by the 11 March 2011 Mw9.0 Tohoku-Oki megathrust earthquake

Tae-Kyung Hong, Ilgoo Kim, Seongjun Park & Dongwoo Kil
The mass dislocations caused by large coseismic slips in megathrust earthquakes are large enough to produce elastogravity waves. Despite successful identification of elastogravity-wave development during megathrust earthquakes, the nature of ground motions and hazard potentials in regional and teleseismic distances remains unknown. The dynamic ground motions from the 11 March 2011 MW9.0 Tohoku-Oki megathrust earthquake are retrieved from broadband seismic records throughout the Korean Peninsula. The dynamic ground motions of the megathrust earthquake are dominated...

Data from: Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study

Young-Jun Rhie, Jae-Ho Yoo, Jin-Ho Choi, Hyun-Wook Chae, Jae Hyun Kim, Sochung Chung, , Choong Ho Shin, Eun Young Kim & Ho-Seong Kim
Purpose The aim of this registry study was to analyze the long-term safety and effectiveness of recombinant human growth hormone (rhGH) in South Korean pediatric patients (≥2 years of age) with growth hormone deficiency GHD) of idiopathic or organic etiology, idiopathic short stature, Turner syndrome, small for gestational age and chronic renal failure. Methods The study patients were followed-up till two years after the epiphyseal closure, with visits scheduled every six months. The outcome measures...

Data from: Ambient noise tomography of upper crustal structures and Quaternary faults in the Seoul metropolitan area and its geological implications

Dongwoo Kil, Tae-Kyung Hong, Dongchan Chung, Byeongwoo Kim, Junhyung Lee & Seongjun Park
We investigate the upper-crustal seismic velocity structure in the Seoul metropolitan area, where about 20 million people live. The Chugaryeong fault zone (CFZ) is placed in this area, but the seismic hazard potential remains unclear. We conducted ambient noise tomography to illuminate the high-resolution upper-crustal structure in the Seoul metropolitan area. We analyzed continuous vertical seismic records for ~5 months from a dense seismic array with 77 broadband stations. Group velocity dispersion curves and tomographic...

Social determinants associated with loss of an eye in the United States using the All of Us nationwide database

Alison X. Chan, Bharanidharan Radha Saseendrakumar, Daniel J. Ozzello, Michelle Ting, Jin Sook Yoon, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa & Sally L. Baxter
To identify common factors associated with the loss of an eye using the NIH All of Us database. In this case-controlled study, we extracted electronic health record and socio-demographic data for 231 cases of eye loss from All of Us enrollment sites. Controls (N = 924) matched the demographic characteristics of the 2020 United States Census. Bivariate analyses and multivariable logistic regression identified variables significantly associated with increased odds of eye loss. Medical and social...

Additional file 1 of The Korean undiagnosed diseases program phase I: expansion of the nationwide network and the development of long-term infrastructure

Soo Yeon Kim, Seungbok Lee, Hyewon Woo, Jiyeon Han, Young Jun Ko, Youngkyu Shim, Soojin Park, Se Song Jang, Byung Chan Lim, Jung Min Ko, Ki Joong Kim, Anna Cho, Hunmin Kim, Hee Hwang, Ji Eun Choi, Man Jin Kim, Jangsup Moon, Moon-Woo Seong, Sung Sup Park, Sun Ah Choi, Ji Eun Lee, Young Se Kwon, Young Bae Sohn, Jon Soo Kim, Won Seop Kim … & Jong-Hee Chae
Additional file 1. Detailed information of genetically confirmed patients.

Additional file 1 of Enterotypical Prevotella and three novel bacterial biomarkers in preoperative stool predict the clinical outcome of colorectal cancer

Ji-Won Huh, Min Jung Kim, Jaesik Kim, Hyeon Gwon Lee, Seung-Bum Ryoo, Ja-Lok Ku, Seung-Yong Jeong, Kyu Joo Park, Dokyoon Kim, Jihyun F. Kim & Ji Won Park
Additional file 1: Table S1. Clinical data of patients with primary CRC.

Additional file 1 of High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration

Sehui Kim, Jaemoon Koh, Seung Geun Song, Jeemin Yim, Miso Kim, Bhumsuk Keam, Young Tae Kim, Jihun Kim, Doo Hyun Chung & Yoon Kyung Jeon
Additional file 1: Supplementary Data S1. Clinicopathological features and immunoprofiles of patients with lung adenocarcinoma subjected to flow cytometry. Supplementary Data S2. Clinicopathological features and immune profiles of patients with lung adenocarcinoma subjected to immunohistochemistry. Supplementary Data S3. Clinicopathological features and immune profiles of patients with lung squamous cell carcinoma subjected to immunohistochemistry. Supplementary Data S4. Clinicopathological features and immune profiles of patients with colon adenocarcinoma subjected to immunohistochemistry. Supplementary Data S5. Clinicopathological features and...

Naoxintong accelerates diabetic wound healing by attenuating inflammatory response

Leyu Fang, Lu Chen, Min Song, Juan He, Lusha Zhang, Chunxiao Li, Qianyi Wang, Wenjie Yang, Wei Sun, Yuze Leng, Hong Shi, Shaoxia Wang, Xiumei Gao & Hong Wang
Naoxintong (NXT), a prescribed traditional Chinese medicine, widely used in cerebrovascular and cardiovascular diseases, could be effective in diabetic wounds. This study evaluates the wound healing activity of NXT by employing an excisional wound splinting model. NXT was dissolved in saline and given daily by gavage. Wounds were induced at the dorsum of non-diabetic (db/+) and diabetic (db/db) mice and treated with saline or 700 mg/kg/d NXT for 16 days. Wound closure was measured every...

Data from: The thermoelectric properties of Au nanoparticle-incorporated Al-doped mesoporous ZnO thin films

Min-Hee Hong, Wooje Han, Kyu-Yeon Lee & Hyung-Ho Park
Mesoporous Al-doped ZnO thin films incorporated with gold nanoparticles (Au NPs) were synthesized using a sol-gel and evaporation-induced self-assembly process. In this work, the complementary effects of Au NP incorporation and Al doping on the mesoporous ZnO thin films’ thermoelectric properties were analyzed. The incorporated Au NPs induced an increase in electrical conductivity but a detriment in the pore arrangement of the mesoporous ZnO thin film, which was accompanied by a decrease in porosity. However,...

Data from: Global induced stress field from large earthquakes since 1900 and chained earthquake occurrence

Junhyung Lee & Tae-Kyung Hong
Great earthquakes produce significant damages over large areas. The timely identification of impending earthquakes is crucial for seismic hazard mitigation. We assess the stress induced from neighboring earthquakes for 120 years around the circum-Pacific plate boundaries. Large earthquakes perturbed the stress fields. We analyze 1,636 earthquakes with moment magnitudes greater than or equal to 6.4 in 1900-2020. The cumulative Coulomb stress changes reach up to the order of tens to hundreds of bar at the...

Additional file 2 of Optical genome mapping identifies clinically relevant genomic rearrangements in prostate cancer biopsy sample

Yeeun Shim, Jongsoo Lee, Jieun Seo, Cheol Keun Park, Saeam Shin, Hyunho Han, Seung-Tae Lee, Jong Rak Choi, Byung Ha Chung & Young Deuk Choi
Additional file 2: Table S1. Genome mapping summary. Table S2. All non-masked CNVs called by Bionano Analysis Pipeline. Table S3. All SVs called by Bionano Analysis Pipeline.

Additional file 2 of Association between CYP2D6 phenotype and recurrence of Plasmodium vivax infection in south Korean patients

Sungim Choi, Heun Choi, Seong Yeon Park, Yee Gyung Kwak, Je Eun Song, So Youn Shin, Ji Hyeon Baek, Hyun-IL Shin, Shin-Hyung Cho, Sang-Eun Lee, Jeong-Ran Kwon, Sookkyung Park, Miyoung Kim, Hong Sang Oh, Yong Chan Kim, Min Jae Kim & Joon-Sup Yeom
Additional file 2: Table S2. The CYP2D6 alleles of the entire samples defined by tagging single nucleotide polymorphisms (tSNPs).

Data from: Catastrophic health expenditure according to employment status in South Korea: A population-based panel study

Jae-Woo Choi, Tae Hyun Kim, Sung-In Jang, Suk-Yong Jang, Woorim Kim & Eun-Cheol Park
Objectives: Catastrophic health expenditure (CHE) means that medical spending of a household exceeds a certain level of capacity to pay. Previous studies of CHE have focused on benefits supported by the public sector or high medical cost incurred by treating diseases in South Korea. This study examines variance of CHE in these households according to changes in employment status. We also determine whether a relationship exists according to income level. Design: A longitudinal study. Setting:...

Data from: Phosphate is a potential biomarker of disease severity and predicts adverse outcomes in acute kidney injury patients undergoing continuous renal replacement therapy

Su-Young J Jung, Jaeyeol Kwon, Seohyun Park, Jong Hyun Jhee, Hae-Ryong Yun, HyoungNae Kim, Youn Kyung Kee, Chang-Yun Yoon, Tae-Ik Chang, Ea Wha Kang, Jung Tak Park, Tae-Hyun Yoo, Shin-Wook Kang & Seung Hyeok Han
Hyperphosphatemia is associated with mortality in patients with chronic kidney disease, and is common in critically ill patients with acute kidney injury (AKI); however, its clinical implication in these patients is unknown. We conducted an observational study in 1144 patients (mean age, 63.2 years; male, 705 [61.6%]) with AKI who received continuous renal replacement therapy (CRRT) between January 2009 and September 2016. Phosphate levels were measured before (0 h) and 24 h after CRRT initiation....

Neural and social correlates of attitudinal brokerage: using the complete social networks of two entire villages

Yoosik Youm, Junsol Kim, Seyul Kwak & Jeanyung Chey
To avoid polarization and maintain small-worldness in society, people who act as attitudinal brokers are critical. These people maintain social ties with people who have dissimilar and even incompatible attitudes. Based on resting-state functional magnetic resonance imaging (n=139) and the complete social networks from two Korean villages (n=1508), we investigated the individual-level neural capacity and social-level structural opportunity for attitudinal brokerage regarding gender role attitudes. First, using a connectome-based predictive model, we successfully identified the...

Data from: Birt-Hogg-Dube syndrome prospectively detected by review of chest computed tomography scans

Hye Jung Park, Chul Hwan Park, Sang Eun Lee, Geun Dong Lee, Min Kwang Byun, Sungsoo Lee, Kyung-A Lee, Tae Hoon Kim, Seong Han Kim, Seo Yeon Yang, Hyung Jung Kim & Chul Min Ahn
Purpose: Birt-Hogg-Dube syndrome (BHD) is a rare disorder caused by mutations in the gene that encodes folliculin (FLCN) and is inherited in an autosomal dominant manner. BHD is commonly accompanied by fibrofolliculomas, renal tumors, multiple pulmonary cysts, and spontaneous pneumothorax. The aim of this study was to detect BHD prospectively in patients undergoing chest computed tomography (CT) scans and to evaluate further the characteristics of BHD in Korea. Methods: We prospectively checked and reviewed the...

Naoxintong accelerates diabetic wound healing by attenuating inflammatory response

Leyu Fang, Lu Chen, Min Song, Juan He, Lusha Zhang, Chunxiao Li, Qianyi Wang, Wenjie Yang, Wei Sun, Yuze Leng, Hong Shi, Shaoxia Wang, Xiumei Gao & Hong Wang
Naoxintong (NXT), a prescribed traditional Chinese medicine, widely used in cerebrovascular and cardiovascular diseases, could be effective in diabetic wounds. This study evaluates the wound healing activity of NXT by employing an excisional wound splinting model. NXT was dissolved in saline and given daily by gavage. Wounds were induced at the dorsum of non-diabetic (db/+) and diabetic (db/db) mice and treated with saline or 700 mg/kg/d NXT for 16 days. Wound closure was measured every...

Data from: Video education versus face-to-face education on inhaler technique for patients with well-controlled or partly-controlled asthma: a phase IV, open-label, non-inferiority, multicenter, randomized, controlled trial

Hye Jung Park, Min Kwang Byun, Jae-Woo Kwon, Woo Kyung Kim, Dong-Ho Nahm, Myung-Goo Lee, Sang-Pyo Lee, Sook Young Lee, Ji-Hyun Lee, Yi Yeong Jeong, You Sook Cho, Jeong-Hee Choi & Byoung Whui Choi
Background: Education on inhaler technique is critical for effective asthma treatment. However, traditionally used face-to-face education is a time-consuming, costly, and often laborious. The current study evaluated the efficacy of a newly developed video-based inhaler technique education method. Methods: A total of 184 subjects with well-controlled or partly-controlled asthma were enrolled from 12 hospitals in South Korea from 30 November 2015 to 01 June 2016. Subjects were randomly divided into two groups in a 1:1...

Data from: Social brain volume is associated with in-degree social network size among older adults

Seyul Kwak, Won-Tak Joo, Yoosik Youm & Jeanyung Chey
The social brain hypothesis proposes that large neocortex size evolved to support cognitively demanding social interactions. Accordingly, previous studies have observed that larger orbitofrontal and amygdala structures predict the size of an individual's social network. However, it remains uncertain how an individual's social connectedness reported by other people is associated with the social brain volume. In this study, we found that a greater in-degree network size, a measure of social ties identified by a subject's...

Platinum incorporation into titanate perovskites to deliver emergent active and stable platinum nanoparticles (dataset)

Maadhav Kothari, Yukwon Jeon & John Thomas Sirr Irvine

Data from: Effects of Lewy body disease and Alzheimer’s disease on brain atrophy and cognitive dysfunction

Sung Woo Kang, Seun Jeon, Han Soo Yoo, Seok Jong Chung, Phil Hyu Lee, Young H. Sohn, Mijin Yun, Alan C. Evans & Byoung Seok Ye
Objectives: We investigated the independent and interaction effects of Alzheimer’s disease (AD) and Lewy body disease (LBD) on cognition and brain atrophy. Methods: We consecutively recruited 38 controls and 108 patients with AD-related cognitive impairment (ADCI) and/or LBD-related cognitive impairment (LBCI) from university-based dementia and movement clinics. Diagnoses of ADCI and LBCI were supported by 18F-Florbetaben PET and 18F-FP-CIT-PET, respectively. There were 38 controls, 26 patients with pure ADCI (18 mild cognitive impairment (MCI) and...

Supplement: Multicenter validated detection of focal cortical dysplasia using deep learning

Ravnoor S Gill, Hyo M Lee, Benoit Caldairou, Seok-Jun Hong, Carmen Barba, Francesco Deleo, Ludovico D’Incerti, Vanessa C Mendes Coelho, Matteo Lenge, Mira Semmelroch, Dewi Schrader, Fabrice Bartolomei, Maxime Guye, Andreas Schulze-Bonhage, Horst Urbach, Kyoo Ho Cho, Fernando Cendes, Renzo Guerrini, Graeme Jackson, R Edward Hogan, Neda Bernasconi & Andrea Bernasconi
Objective. To test the hypothesis that a multicenter-validated computer deep learning algorithm detects MRI-negative focal cortical dysplasia (FCD). Methods. We used clinically acquired 3D T1-weighted and 3D FLAIR MRI of 148 patients (median age, 23 years [range, 2-55]; 47% female) with histologically verified FCD at nine centers to train a deep convolutional neural network (CNN) classifier. Images were initially deemed as MRI-negative in 51% of cases, in whom intracranial EEG determined the focus. For risk...

Social determinants associated with loss of an eye in the United States using the All of Us nationwide database

Alison X. Chan, Bharanidharan Radha Saseendrakumar, Daniel J. Ozzello, Michelle Ting, Jin Sook Yoon, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa & Sally L. Baxter
To identify common factors associated with the loss of an eye using the NIH All of Us database. In this case-controlled study, we extracted electronic health record and socio-demographic data for 231 cases of eye loss from All of Us enrollment sites. Controls (N = 924) matched the demographic characteristics of the 2020 United States Census. Bivariate analyses and multivariable logistic regression identified variables significantly associated with increased odds of eye loss. Medical and social...

Additional file 2 of Association between CYP2D6 phenotype and recurrence of Plasmodium vivax infection in south Korean patients

Sungim Choi, Heun Choi, Seong Yeon Park, Yee Gyung Kwak, Je Eun Song, So Youn Shin, Ji Hyeon Baek, Hyun-IL Shin, Shin-Hyung Cho, Sang-Eun Lee, Jeong-Ran Kwon, Sookkyung Park, Miyoung Kim, Hong Sang Oh, Yong Chan Kim, Min Jae Kim & Joon-Sup Yeom
Additional file 2: Table S2. The CYP2D6 alleles of the entire samples defined by tagging single nucleotide polymorphisms (tSNPs).

Additional file 1 of The Korean undiagnosed diseases program phase I: expansion of the nationwide network and the development of long-term infrastructure

Soo Yeon Kim, Seungbok Lee, Hyewon Woo, Jiyeon Han, Young Jun Ko, Youngkyu Shim, Soojin Park, Se Song Jang, Byung Chan Lim, Jung Min Ko, Ki Joong Kim, Anna Cho, Hunmin Kim, Hee Hwang, Ji Eun Choi, Man Jin Kim, Jangsup Moon, Moon-Woo Seong, Sung Sup Park, Sun Ah Choi, Ji Eun Lee, Young Se Kwon, Young Bae Sohn, Jon Soo Kim, Won Seop Kim … & Jong-Hee Chae
Additional file 1. Detailed information of genetically confirmed patients.

Registration Year

  • 2022
    12
  • 2021
    12
  • 2020
    2
  • 2019
    3
  • 2018
    4
  • 2017
    1
  • 2016
    1

Resource Types

  • Dataset
    35

Affiliations

  • Yonsei University
    35
  • Seoul National University
    11
  • Severance Hospital
    7
  • Seoul National University Hospital
    6
  • University of Pennsylvania
    4
  • Seoul National University Bundang Hospital
    4
  • Ajou University
    4
  • Dongguk University Ilsan Hospital
    3
  • University of Ulsan
    3
  • University of British Columbia
    3