2 Works

Data from: Socioeconomic determinants of outcome after childhood arterial ischemic stroke

Lori C. Jordan, Nancy K. Hills, Christine K. Fox, Rebecca N. Ichord, Paola Pergami, Gabrielle A. DeVeber, Heather J. Fullerton & Warren Lo
Objective: To determine whether lower socioeconomic status (SES) is associated with worse one-year neurological outcomes and reduced access to rehabilitation services in children with arterial ischemic stroke (AIS). Methods: From 2010-2014, Vascular Effects of Infection in Pediatric Stroke observational study prospectively enrolled and confirmed 355 children (29 days -18 years) with AIS at 37 international centers. SES markers measured via parental interview included annual household income (US dollars (USD)) at time of enrollment, maternal education...

Data from: Clinical spectrum of STX1B-related epileptic disorders

Stefan Wolking, Patrick May, Davide Mei, Rikke S. Møller, Simona Balestrini, Katherine L. Helbig, Cecilia Desmettre Altuzarra, Nicolas Chatron, Charu Kaiwar, Katharina Stoehr, Peter Widdess-Walsh, Bryce A. Mendelsohn, Adam Numis, Maria R. Cilio, Wim Van Paesschen, Lene L. Svendsen, Stephanie Oates, Elaine Hughes, Sushma Goyal, Kathleen Brown, Margarita Sifuentes Saenz, Thomas Dorn, Hiltrud Muhle, Alistair T. Pagnamenta, Dimitris V. Vavoulis … & Julian Schubert
Objective: The aim of this study was to expand the spectrum of epilepsy syndromes related to STX1B, encoding the presynaptic protein syntaxin-1B, and establish genotype-phenotype correlations by identifying further disease-related variants. Methods: We used next generation sequencing in the framework of research projects and diagnostic testing. Clinical data and EEGs were reviewed, including already published cases. To estimate the pathogenicity of the variants, we used established and newly developed in silico prediction tools. Results: We...

Registration Year

  • 2018
    2

Resource Types

  • Dataset
    2

Affiliations

  • Children's Hospital of Philadelphia
    2
  • University of California, San Francisco
    2
  • Massachusetts General Hospital
    1
  • Nationwide Children's Hospital
    1
  • University of Antwerp
    1
  • Hvidovre Hospital
    1
  • Children's Hospital Colorado
    1
  • Lyon Neuroscience Research Center
    1
  • University of Milan
    1
  • Newcastle University
    1