30 Works

LncRNA-UCA1 regulates lung adenocarcinoma progression through competitive binding to miR-383

Li Tang, Sheng Wang, Yapeng Wang, Kang Li & Qiang Li
The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in vitro experiments. The expression profile of lncRNA-UCA1 was analyzed by genome-wide analysis from GSE146459. The cell counting Kit-8, colony formation, wound healing and transwell assays were performed to evaluate the effects of lncRNA-UCA1 in vitro. In addition, luciferase reporter assays were...

Additional file 3 of The effectiveness of postpartum interventions aimed at improving women’s mental health after medical complications of pregnancy: a systematic review and meta-analysis

Jie Shang, Nadila Dolikun, Xuanchen Tao, Puhong Zhang, Mark Woodward, Maree L. Hackett & Amanda Henry
Supplementary Material 3

Additional file 7 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 7: Table S7. Differentially expressed genes that appeared in both RNA-seq data and the GSE159676 datasets

Additional file 1 of Incorporating a gender lens into nutrition and health-related policies in Fiji: analysis of policies and stakeholder perspectives

Briar L. McKenzie, Gade Waqa, Sarah Mounsey, Claire Johnson, Mark Woodward, Kent Buse, Anne Marie Thow, Rachael McLean & Jacqui Webster
Additional file 1: Supplementary table 1. Policy content analysis and WHO gender analysis, data extraction.

Additional file 4 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 4: Table S4. The top 20 significantly KEGG pathways of RNA-seq data.

Additional file 6 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 6: Table S6. Results of GO enrichment on differentially expressed genes from GSE159676 datasets.

Additional file 1 of The effectiveness of postpartum interventions aimed at improving women’s mental health after medical complications of pregnancy: a systematic review and meta-analysis

Jie Shang, Nadila Dolikun, Xuanchen Tao, Puhong Zhang, Mark Woodward, Maree L. Hackett & Amanda Henry
Supplementary Material 1

Additional file 3 of The effectiveness of postpartum interventions aimed at improving women’s mental health after medical complications of pregnancy: a systematic review and meta-analysis

Jie Shang, Nadila Dolikun, Xuanchen Tao, Puhong Zhang, Mark Woodward, Maree L. Hackett & Amanda Henry
Supplementary Material 3

Impact of Coronary Artery Disease on The Outcomes of Catheter Ablation in Patients with Atrial Fibrillation

Fuqian Guo, Caiying Li, Chen Chen, Jiqiong Ni, Lan Yang, Yicheng Chen, Rong Fu, Yang Jiao, Yuanyuan Meng & Bulang Gao
ABSTRACT Introduction: The objective of this study is to investigate the possible impact of coronary artery disease (CAD) on clinical outcomes of catheter ablation in patients with atrial fibrillation (AF). Methods: Patients with AF who underwent coronary computed tomography and catheter ablation were enrolled. The presence of stenotic severity and plaque, characteristics of coronary arteries, clinical data, and adverse outcomes of catheter ablation were analysed. Results: A total of 243 patients were enrolled, 100 (41%)...

The novel outer membrane protein from OprD/Occ family is associated with hypervirulence of carbapenem resistant Acinetobacter baumannii ST2/KL22

Mingxi Hua, Jingyuan Liu, Pengcheng Du, Xinzhe Liu, Min Li, Huizhu Wang, Chen Chen, Xinmin Xu, Yu Jiang, Yajie Wang, Hui Zeng & Ang Li
Acinetobacter baumannii has become a major healthcare threat that causes nosocomial infections, especially in critically ill patients. The spread of carbapenem resistant A. baumannii (CRAB) strains has long been a clinical concern. It is important to study the epidemiology and virulence characteristics of different CRAB isolates in order to tailor infection prevention and antibiotic prescribing. In this study, a total of 71 CRAB isolates were collected in the hospital, and clinical characteristics of infections were...

MicroRNA expression profile and identification of novel microRNA biomarkers for metabolic syndrome

Guanzhi Liu, Yutian Lei, Sen Luo, Zhuo Huang, Chen Chen, Kunzheng Wang, Pei Yang & Xin Huang
The lack of efficient biomarkers is the main reason for the inaccurate early diagnosis and poor treatment outcomes of patients with metabolic syndrome (MetS). The current study aimed to identify several novel microRNA (miRNA) biomarkers for metabolic syndrome via high-throughput sequencing and comprehensive bioinformatics analysis. Through high-throughput sequencing and differentially expressed miRNA (DEM) analysis, we first identified two upregulated and 36 downregulated DEMs in the plasma samples of patients with MetS compared to the healthy...

MicroRNA expression profile and identification of novel microRNA biomarkers for metabolic syndrome

Guanzhi Liu, Yutian Lei, Sen Luo, Zhuo Huang, Chen Chen, Kunzheng Wang, Pei Yang & Xin Huang
The lack of efficient biomarkers is the main reason for the inaccurate early diagnosis and poor treatment outcomes of patients with metabolic syndrome (MetS). The current study aimed to identify several novel microRNA (miRNA) biomarkers for metabolic syndrome via high-throughput sequencing and comprehensive bioinformatics analysis. Through high-throughput sequencing and differentially expressed miRNA (DEM) analysis, we first identified two upregulated and 36 downregulated DEMs in the plasma samples of patients with MetS compared to the healthy...

LncRNA-UCA1 regulates lung adenocarcinoma progression through competitive binding to miR-383

Li Tang, Sheng Wang, Yapeng Wang, Kang Li & Qiang Li
The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in vitro experiments. The expression profile of lncRNA-UCA1 was analyzed by genome-wide analysis from GSE146459. The cell counting Kit-8, colony formation, wound healing and transwell assays were performed to evaluate the effects of lncRNA-UCA1 in vitro. In addition, luciferase reporter assays were...

Additional file 2 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 2: Table S2. RNA-seq data of liver tissues of NAFLD patients and controls.

Additional file 3 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 3: Table S3. Results of GO enrichment on differentially expressed genes from RNA-seq data.

Additional file 5 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 5: Table S5. Results of KEGG enrichment on differentially expressed genes from GSE159676 datasets.

Additional file 6 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 6: Table S6. Results of GO enrichment on differentially expressed genes from GSE159676 datasets.

The novel outer membrane protein from OprD/Occ family is associated with hypervirulence of carbapenem resistant Acinetobacter baumannii ST2/KL22

Mingxi Hua, Jingyuan Liu, Pengcheng Du, Xinzhe Liu, Min Li, Huizhu Wang, Chen Chen, Xinmin Xu, Yu Jiang, Yajie Wang, Hui Zeng & Ang Li
Acinetobacter baumannii has become a major healthcare threat that causes nosocomial infections, especially in critically ill patients. The spread of carbapenem-resistant A. baumannii (CRAB) strains has long been a clinical concern. It is important to study the epidemiology and virulence characteristics of different CRAB isolates in order to tailor infection prevention and antibiotic prescribing. In this study, a total of 71 CRAB isolates were collected in the hospital, and clinical characteristics of infections were analyzed....

Blood pressure and dementia

Ruth Peters, Jane Warwick, Kaarin J. Anstey & Craig S. Anderson
High blood pressure (BP) has been associated with an increased risk of cerebrovascular disease, stroke, and Alzheimer disease pathology. Epidemiologic studies are consistent in showing that high BP, particularly in midlife, is a risk factor for the development of dementia in late life. However, supporting randomized evidence of the inference that BP-lowering therapy can prevent dementia has been slow in coming over the last 30 years. The most recent randomized trial, the Systolic Blood Pressure...

Additional file 1 of Incorporating a gender lens into nutrition and health-related policies in Fiji: analysis of policies and stakeholder perspectives

Briar L. McKenzie, Gade Waqa, Sarah Mounsey, Claire Johnson, Mark Woodward, Kent Buse, Anne Marie Thow, Rachael McLean & Jacqui Webster
Additional file 1: Supplementary table 1. Policy content analysis and WHO gender analysis, data extraction.

Additional file 1 of The effectiveness of postpartum interventions aimed at improving women’s mental health after medical complications of pregnancy: a systematic review and meta-analysis

Jie Shang, Nadila Dolikun, Xuanchen Tao, Puhong Zhang, Mark Woodward, Maree L. Hackett & Amanda Henry
Supplementary Material 1

Additional file 2 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 2: Table S2. RNA-seq data of liver tissues of NAFLD patients and controls.

Additional file 4 of Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan & Jiequn Li
Additional file 4: Table S4. The top 20 significantly KEGG pathways of RNA-seq data.

Impact of Coronary Artery Disease on The Outcomes of Catheter Ablation in Patients with Atrial Fibrillation

Fuqian Guo, Caiying Li, Chen Chen, Jiqiong Ni, Lan Yang, Yicheng Chen, Rong Fu, Yang Jiao, Yuanyuan Meng & Bulang Gao
ABSTRACT Introduction: The objective of this study is to investigate the possible impact of coronary artery disease (CAD) on clinical outcomes of catheter ablation in patients with atrial fibrillation (AF). Methods: Patients with AF who underwent coronary computed tomography and catheter ablation were enrolled. The presence of stenotic severity and plaque, characteristics of coronary arteries, clinical data, and adverse outcomes of catheter ablation were analysed. Results: A total of 243 patients were enrolled, 100 (41%)...

The novel outer membrane protein from OprD/Occ family is associated with hypervirulence of carbapenem resistant Acinetobacter baumannii ST2/KL22

Mingxi Hua, Jingyuan Liu, Pengcheng Du, Xinzhe Liu, Min Li, Huizhu Wang, Chen Chen, Xinmin Xu, Yu Jiang, Yajie Wang, Hui Zeng & Ang Li
Acinetobacter baumannii has become a major healthcare threat that causes nosocomial infections, especially in critically ill patients. The spread of carbapenem-resistant A. baumannii (CRAB) strains has long been a clinical concern. It is important to study the epidemiology and virulence characteristics of different CRAB isolates in order to tailor infection prevention and antibiotic prescribing. In this study, a total of 71 CRAB isolates were collected in the hospital, and clinical characteristics of infections were analyzed....

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